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1/ Today has brought a lot of news about 'variants', as we discover community transmission of B.1.351 (SA variant) in the UK.
But some of the people who study these genomes have increasingly started focusing on a different concept: 'constellations', which may be more useful.
2/ We're actually all using 'variant' wrong anyway – we're using it to refer to a 'lineage'. A lineage is a set of viruses descended from a common ancestor. All B.1.1.7 (UK variant) viruses descend from an infection that probably occurred in August or September.
3/ But what makes this lineage practically important is that it carries a set of mutations which make it more transmissible.
I.e. we don't really care about the ancestry in itself.
4/ For example, one of the mutations that we think is important to B.1.1.7's faster transmission is called N501Y.
5/ It turns out that a lot of the lineages identified as important recently, in Brazil, South Africa, and the UK, have mutations such as N501Y in common (figure adapted from https://t.co/lpJeW0GGnU)
But some of the people who study these genomes have increasingly started focusing on a different concept: 'constellations', which may be more useful.

2/ We're actually all using 'variant' wrong anyway – we're using it to refer to a 'lineage'. A lineage is a set of viruses descended from a common ancestor. All B.1.1.7 (UK variant) viruses descend from an infection that probably occurred in August or September.
3/ But what makes this lineage practically important is that it carries a set of mutations which make it more transmissible.
I.e. we don't really care about the ancestry in itself.
4/ For example, one of the mutations that we think is important to B.1.1.7's faster transmission is called N501Y.
5/ It turns out that a lot of the lineages identified as important recently, in Brazil, South Africa, and the UK, have mutations such as N501Y in common (figure adapted from https://t.co/lpJeW0GGnU)

This is also the Rochester Police - dreadful mishandling of an altered mental status call - which led to their current crisis team, which was unavailable (and they didn't wait for in a low threat situation as they could have) for this 9 y/o!
https://t.co/UU2lUxD7Hd
https://t.co/UU2lUxD7Hd
In both cases there is a failure to use good judgement, make a valid threat assessment, to match in force to situation, failure to choose to wait for safer and appropriate staff/conditions and to use their time wisely. They also treat 'perp' as more object than human.
https://t.co/qoCofP6Rdt
By the way... Rochester is near Buffalo - where this happened...
https://t.co/UU2lUxD7Hd
https://t.co/UU2lUxD7Hd
In both cases there is a failure to use good judgement, make a valid threat assessment, to match in force to situation, failure to choose to wait for safer and appropriate staff/conditions and to use their time wisely. They also treat 'perp' as more object than human.
https://t.co/qoCofP6Rdt
By the way... Rochester is near Buffalo - where this happened...
EV Charging - A thread on the segment of charging infrastructure & stocks including
$TPGY $SBE $CLII $BLNK $NBAC $BEEM $STPK $TSLA $IDEX
According to the International Energy Agency, which forecasts that there may be 300-400 million EVs (cars + commercial) on the road out of approximately 2 billion vehicles by 2040.
The global electric vehicle charging infrastructure market size was valued at USD 15.06 billion in 2020 and is expected to grow at a compound annual growth rate (CAGR) of 33.4% from 2021 to 2028.
In 2019, there were about 7.3 million chargers worldwide, of which about 6.5 million were private. US alone needs about 2 million EV charging stations for the 40 or more electric car models that are likely to be on the roads in their multitudes by 2025. China leads the market.
According to the Open Charge Map, there are almost 200K charging stations across about 100K locations around the world.
https://t.co/0ToXKV9h8E
$TPGY $SBE $CLII $BLNK $NBAC $BEEM $STPK $TSLA $IDEX

According to the International Energy Agency, which forecasts that there may be 300-400 million EVs (cars + commercial) on the road out of approximately 2 billion vehicles by 2040.

The global electric vehicle charging infrastructure market size was valued at USD 15.06 billion in 2020 and is expected to grow at a compound annual growth rate (CAGR) of 33.4% from 2021 to 2028.

In 2019, there were about 7.3 million chargers worldwide, of which about 6.5 million were private. US alone needs about 2 million EV charging stations for the 40 or more electric car models that are likely to be on the roads in their multitudes by 2025. China leads the market.

According to the Open Charge Map, there are almost 200K charging stations across about 100K locations around the world.
https://t.co/0ToXKV9h8E
