1/

Get a cup of coffee.

In this thread, I'll help you understand the basics of Binomial Thinking.

The future is always uncertain. There are many different ways it can unfold -- some more likely than others. Binomial thinking helps us embrace this view.

2/

The S&P 500 index is at ~3768 today.

Suppose we want to predict where it will be 10 years from now.

Historically, we know that this index has returned ~10% per year.

If we simply extrapolate this, we get an estimate of ~9773 for the index 10 years from now:
3/

What we just did is called a "point estimate" -- a prediction about the future that's a single number (9773).

But of course, we know the future is uncertain. It's impossible to predict it so precisely.

So, there's a sense of *false precision* in point estimates like this.
4/

To emphasize the uncertainty inherent in such predictions, a better approach is to predict a *range* of values rather than a single number.

For example, we may say the index will return somewhere in the *range* of 8% to 12% (instead of a fixed 10%) per year.
5/

10 years from now, this implies an index value in the *range* [8135, 11703]:
6/

A range is more nuanced than a point estimate, but we still have a problem:

Range estimates tell us nothing about the relative likelihoods of different parts of the range.

For example, which is more likely -- the low end or high end of the range? We don't know.
7/

Ideally, we want to say something like:

10 years from now, there's a ~93% chance that the index will lie in the range [5648, 15244], and there are 60/40 odds favoring the bottom half of this range.

Binomial thinking enables us to make such *probabilistic* predictions.
8/

With binomial thinking, we can derive not just a *range* of possible outcomes, but also the *probability* of seeing each outcome in this range.

It's easiest to illustrate this with an example.
9/

Imagine that you just joined the Dunder Mifflin Paper Company as a Salesman.

From these humble beginnings, you hope to rise quickly within the organization.

You want to become the CEO in 6 years time.

Here's your path to the top job:
10/

So, you need 5 promotions to become the CEO.

Let's say you come up for a promotion every year.

And every year, there's a 75% chance you'll get the promotion (and a 25% chance you won't).

So, what's the probability that you'll achieve your goal of becoming CEO in 6 years?
11/

Let's tackle this one year at a time.

At the end of your first year on the job, you come up for a promotion.

If you get it, you become Assistant To the Regional Manager (ATRM). If not, you remain Salesman (S). The odds are 75/25.
12/

So, at the end of Year 1, there are 2 possible states you could be in: S (Salesman) and ATRM (Assistant To the Regional Manager).

S has a 25% probability and ATRM has a 75% probability.
13/

Similarly, at the end of Year 2, you again come up for a promotion.

Depending on whether you get it, there are now 3 possible states you could be in: S, ATRM, and ARM.

Again, each state has a probability (in pink below):
14/

Continuing this way, we can draw up all the career trajectories you can possibly follow during your first 6 years at Dunder Mifflin.

In some of these trajectories, you achieve your goal of becoming CEO. In others, you don't.
15/

And by simply propagating the 75/25 probabilities all the way down, we find that your probability of becoming CEO within 6 years is ~53.39%:
16/

This example illustrates some key features of binomial thinking.

Feature 1. Break time into small chunks.

For example, in this case, we broke your first 6 years at Dunder Mifflin into 6 1-year chunks.
17/

Feature 2. At the end of each time chunk, figure out all possible states we can be in.

For example, at the end of Year 2 at Dunder Mifflin, your possible states are: S, ATRM, and ARM.
18/

Feature 3. At each possible state, consider 2 possible scenarios and where each one leads.

The scenarios could be getting a promotion or not. The S&P 500 going up or down. An election won by a Democrat or a Republican. A guilty or not guilty court verdict. Etc.
19/

Feature 4. Account for probabilities. Propagate them top-down through the binomial diagram to work out the chances of getting various desirable and undesirable outcomes.
20/

That's pretty much all there is to binomial thinking.

As you've seen, it's a simple way to incorporate chance events and probabilistic outcomes into our analyses.

It's particularly useful when simple point estimates and range estimates prove to be inadequate.
21/

But there are also drawbacks to binomial thinking.

For example, it advocates a binary worldview. At each state, we only account for 2 possible ways the future can unfold (eg, "promotion" vs "no promotion").
22/

But often, there are more than 2 ways.

For example, the S&P 500 may go down 30%, up 5%, up 25%, etc. The possibilities are endless, but binomial logic reduces them to just 2.

Also, in many situations, the binomial diagram becomes pretty big -- and hard to analyze.
23/

But even with these drawbacks, binomial thinking is a definite step up over standard deterministic thinking.

In the land of the blind, the one-eyed man is king.

In the land of point estimators, the binomial thinker is king.
24/

Many financial calculations rely on binomial thinking. Examples include the binomial options pricing model and its cousin Black-Scholes.

Also, this paper by @mjmauboussin uses binomial thinking to value the "optionality" of businesses: https://t.co/3pn0oAWh0H
25/

At every tweet of this thread, you had a binary choice: you could continue reading, or you could skip the rest of the thread.

You're that special person who elected to continue 25 times in a row. A binomial wonder.

Thank you so much!

Have a great weekend.

/End

More from 10-K Diver

More from Science

https://t.co/hXlo8qgkD0
Look like that they got a classical case of PCR Cross-Contamination.
They had 2 fabricated samples (SRX9714436 and SRX9714921) on the same PCR run. Alongside with Lung07. They did not perform metagenomic sequencing on the “feces” and they did not get


A positive oral or anal swab from anywhere in their sampling. Feces came from anus and if these were positive the anal swabs must also be positive. Clearly it got there after the NA have been extracted and were from the very low-level degraded RNA which were mutagenized from

The Taq.
https://t.co/yKXCgiT29w to see SRX9714921 and SRX9714436.
Human+Mouse in the positive SRA, human in both of them. Seeing human+mouse in identical proportions across 3 different sequencers (PRJNA573298, A22, SEX9714436) are pretty straight indication that the originals

Were already contaminated with Human and mouse from the very beginning, and that this contamination is due to dishonesty in the sample handling process which prescribe a spiking of samples in ACE2-HEK293T/A549, VERO E6 and Human lung xenograft mouse.

The “lineages” they claimed to have found aren’t mutational lineages at all—all the mutations they see on these sequences were unique to that specific sequence, and are the result of RNA degradation and from the Taq polymerase errors accumulated from the nested PCR process

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Rig Ved 1.36.7

To do a Namaskaar or bow before someone means that you are humble or without pride and ego. This means that we politely bow before you since you are better than me. Pranipaat(प्राणीपात) also means the same that we respect you without any vanity.

1/9


Surrendering False pride is Namaskaar. Even in devotion or bhakti we say the same thing. We want to convey to Ishwar that we have nothing to offer but we leave all our pride and offer you ourselves without any pride in our body. You destroy all our evil karma.

2/9

We bow before you so that you assimilate us and make us that capable. Destruction of our evils and surrender is Namaskaar. Therefore we pray same thing before and after any big rituals.

3/9

तं घे॑मि॒त्था न॑म॒स्विन॒ उप॑ स्व॒राज॑मासते ।
होत्रा॑भिर॒ग्निं मनु॑षः॒ समिं॑धते तिति॒र्वांसो॒ अति॒ स्रिधः॑॥

Translation :

नमस्विनः - To bow.

स्वराजम् - Self illuminating.

तम् - His.

घ ईम् - Yours.

इत्था - This way.

उप - Upaasana.

आसते - To do.

स्त्रिधः - For enemies.

4/9

अति तितिर्वांसः - To defeat fast.

मनुषः - Yajman.

होत्राभिः - In seven numbers.

अग्निम् - Agnidev.

समिन्धते - Illuminated on all sides.

Explanation : Yajmans bow(do Namaskaar) before self illuminating Agnidev by making the offerings of Havi.

5/9
#ज्योतिष_विज्ञान #मंत्र_विज्ञान

ज्योतिषाचार्य अक्सर ग्रहों के दुष्प्रभाव के समाधान के लिए मंत्र जप, अनुष्ठान इत्यादि बताते हैं।

व्यक्ति के जन्म के समय ग्रहों की स्थिति ही उसकी कुंडली बन जाती है जैसे कि फ़ोटो खींच लिया हो और एडिट करना सम्भव नही है। इसे ही "लग्न" कुंडली कहते हैं।


लग्न के समय ग्रहों की इस स्थिति से ही जीवन भर आपको किस ग्रह की ऊर्जा कैसे प्रभावित करेगी का निर्धारिण होता है। साथ साथ दशाएँ, गोचर इत्यादि चलते हैं पर लग्न कुंडली का रोल सबसे महत्वपूर्ण है।


पृथ्वी से अरबों खरबों दूर ये ग्रह अपनी ऊर्जा से पृथ्वी/व्यक्ति को प्रभावित करते हैं जैसे हमारे सबसे निकट ग्रह चंद्रमा जोकि जल का कारक है पृथ्वी और शरीर के जलतत्व पर पूर्ण प्रभाव रखता है।
पूर्णिमा में उछाल मारता समुद्र का जल इसकी ऊर्जा के प्रभाव को दिखाता है।


अमावस्या में ऊर्जा का स्तर कम होने पर वही समुद्र शांत होकर पीछे चला जाता है। जिसे ज्वार-भाटा कहते हैं। इसी तरह अन्य ग्रहों की ऊर्जा के प्रभाव होते हैं जिन्हें यहां समझाना संभव नहीं।
चंद्रमा की ये ऊर्जा शरीर को (अगर खराब है) water retention, बैचेनी, नींद न आना आदि लक्षण दिखाती है


मंत्र क्या हैं-
मंत्र इन ऊर्जाओं के सटीक प्रयोग करने के पासवर्ड हैं। जिनके जप से संबंधित ग्रह की ऊर्जा को जातक की ऊर्जा से कनेक्ट करके उन ग्रहों के दुष्प्रभाव को कम किया और शुभ प्रभाव को बढ़ाया जाता है।