AGI Significance Paradox: As progress accelerates towards AGI, the number of people who realize the significance of each new breakthrough decreases.

Chess may be a good analogy for explaining the difference between a descriptive model of reality and a generative model of reality.

A descriptive model of chess will describe the rules (i.e. initial setup, allowed moves, points per piece, objectives). This tells you how a chessboard might evolve and also narrows the combinations of realistic chess positions.

In contrast, a generative model involves the actual gameplay between competing players that follow the rules. It generates new styles and patterns. It establishes new strategies and tactics. It generates new openings, middle gameplay, and end game tactics.

A generative model is an evolutionary model that leads to emergent behavior. As a consequence, a master of chess is able to recall the layout of chess positions in a real game in an instant, yet is unable to remember pieces placed in random positions.

That is because causality is present in the movements of pieces in a chessboard. An intuitive system like the human mind is able to capture that causality as a means to understanding and recall.

Constructivism is perhaps the most important idea that will shape the future of humanity. The ills of society are a consequence of the willful ignorance of constructivism.

There are two important definitions of constructivism, one comes from mathematics and the other from psychology. The mathematical definition leads rejects the law of excluded middle. It's relevant in understanding causation.

The psychological definition: "Humans actively construct their own knowledge, and that reality is determined by our experiences as a learner."

The models of causality that our brains invent to navigate the world is a consequence of our progressive development in the world we live in. Robert Kegan calls his theory constructive developmental theory to emphasize two important aspects of cognitive growth.

Cognitive growth is constructive as explained above. It is also developmental in the sense that our mental models of the world make abrupt changes as we grow in maturity. The symmetries in our models break and lead to new symmetries.

Abduction is that thought process where we renew our past, question our present, and reimagine our future.

It was C.S. Peirce, a century ago, that coined the use of this term to describe a thought process that would convey hypothesis making.

A little over 50 years ago, proponents of Artificial Intelligence, proposed that deduction would be the core feature of human intelligence. This idea was driven by the bias towards formal logical systems and the emergence of computers.

This approach was in stark contrast to cybernetics (introduced a decade early) that proposed that dynamical systems were a model for intelligence. The descendant of this approach was coined as artificial neural networks.

This dynamical systems approach was later understood as being similar to an induction based thought process. Deep Learning leads to what can be characterized as Artificial Intuition.

A children's book written in 1954 inspired by Wiener's Cybernetics that explains some common day analog systems:

Analog computation originally meant the construction of a simulation of another system by means of a mechanical or electrical system that represented the same dynamics as the physical system. That is an analog of what's being simulated.

Nobert Wiener generalized this idea in Cybernetics to describe control systems that through negative feedback promoted stability.

W.Ross Ashby argued that negative feedback was insufficient for maintaining the stability (homeostasis) of complex system. Ashby proposed the Law of Requisite Variety.

These machines that 'seem to think' are examples of what was known as analog computation. Cybernetics, control theory, biology are examples of analog computation. But what does this mean other than being the opposite of discrete/digital computation?

JUST IN: The U.S. National Climate Assessment is now public.

This is the report that the Trump Administration doesn’t want you to see. Years in the making, released on the day after Thanksgiving. #ClimateFriday

Here are some of the main

This report is mandated by Congress and focused on the impacts of climate change in the U.S.

Basically: This is what our best scientists think will happen to us as a result of the actions our government is (not) taking to address the most important problem in human history.
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300 experts in 13 federal agencies volunteered their time to make sure you have this information.

Please share it widely.
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The top finding:

“Climate change is projected to significantly affect human health, the economy, and the environment in the United

To expand on that finding:

“In the absence of more significant global mitigation efforts, climate change is projected to impose substantial damages on the U.S. economy, human health, and the environment. ...”
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A Thread about Famous Armenian Inventors and what we have contributed to the world. So the next time someone wants to say we are unimportant, you can rest easy knowing Armenians have contributed some of the greatest inventions to mankind. Here is a handful but there's more.

Raymond Damadian: Armenian-American Physician and inventor of the first MRI machine. MRI is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. Raymond created the first MRI in 1977.

Artem Mikoyan: One of the most famous engineers in aviation. Mikoyan along with Gurevich created one of the most famous Jet lines in history, the MiG. MiG jets directly competed with American Lockheed Martin F Series planes and were among the first to surpass the speed of sound.

Hovannes Adamian: Most notably laid the foundations of color television with his Tri-Color Principle. His work would go on to become the framework that is used to create Color-TV that we see today. He is recognized as one of the founders of color television.

Emik Avakian: An inventor who unfortunately was disabled, but that didn't stop him from contributing work that would help people similar to his condition. Notable contributions are the automatic wheelchair which dismiss the action of hand rolling and a breath operated typewriter.

Solara Active Pharma Science con call was today at 3:30 PM.

@Gautam__Baid @unseenvalue @drprashantmish6 @rdkriplani

Here are the key takeaways of the call. 👇🧵

Business Updates:

• Speed of filing products has been increased. Filed 5 new DMFs – 3 in US and 2 in EU
• Currently ramping up the facility in VIZAG with strong customer attraction, and will be commercialized as planned in Q3
• VIZAG EBIDTA growth guidance changed to 40%+ YoY

• Growth Driver: Broad based growth in other products and Vizag.

• PLI: Company has filed Mysore for PLI scheme for 1 molecule.

• Technology: Company is about to complete its 2 out of 3 technology, which will enhance efficiency for Solara.

Demand in some of sectors is moderated:
• Mgmt expected moderation in demand, hence company has taken necessary steps for those products.

Gross Margins:
• It was down a bit due to product mix however.

Fiscal 2022:
• Solara has grown in regulated market space.
• Vizag will kick in. CRAMS will support tailwind.
• Most of the CRAMS is commercial API.

• Most of the product is expected to be stable both in term of demand and price in the coming few quarter