Today we report the use of base editing in patient-derived cells and in mice to correct the most common cause of progeria, the devastating rapid aging disease. Progeria is typically caused by a dominant negative C•G-to-T•A point mutation in LMNA. 1/11 https://t.co/O7dkEYpndg

1) OBSERVATION: The frequencies are changing. I would have to assess stats on the electromagnetic field to see its fluctuations. All I know is, I am highly sensitive to energy/frequencies, and they are changing, because…

2) 2 Weeks ago, my dog was effected by it as well. He is hearing things that aren’t technically audible. I can tell by his body language and sounds. One week ago I began feeling a pressure in my head and ears. It wasn’t painful at all, but it was intense for a bit.

3) It reminded me of taking off in an airplane a bit. I felt like I was in a vacuum. It went on and off for a couple of days. I’ve picked up on frequencies and high pitched sounds (not audible to most) for 30 years, and today my right ear began to ring for longer than usual.

4) This is nothing unusual for me, with exception of the duration. This happens often with me. No, it’s not tinnitus. Only this time, when I spoke, there was reverb creating a high pitch in my ear from my voice. This lasted for about 30 minutes. It did not hurt, just annoying.

5) So yes, the frequencies are changing. What this means exactly, I am unsure of at the moment. Some will say electromagnetic fields, others will say ascension, and some will say pole shift. I honestly can’t say at this very moment.

1/

Get a cup of coffee.

In this thread, I'll help you understand the basics of Binomial Thinking.

The future is always uncertain. There are many different ways it can unfold -- some more likely than others. Binomial thinking helps us embrace this view.

2/

The S&P 500 index is at ~3768 today.

Suppose we want to predict where it will be 10 years from now.

Historically, we know that this index has returned ~10% per year.

If we simply extrapolate this, we get an estimate of ~9773 for the index 10 years from now:

3/

What we just did is called a "point estimate" -- a prediction about the future that's a single number (9773).

But of course, we know the future is uncertain. It's impossible to predict it so precisely.

So, there's a sense of *false precision* in point estimates like this.

4/

To emphasize the uncertainty inherent in such predictions, a better approach is to predict a *range* of values rather than a single number.

For example, we may say the index will return somewhere in the *range* of 8% to 12% (instead of a fixed 10%) per year.

5/

10 years from now, this implies an index value in the *range* [8135, 11703]: