https://t.co/a7M0zwH9YE
Archived:
https://t.co/s1dZlpHu6A
1. New Chinese Bat Research Thread
Graduate students of the Department of Ecology participate in wildlife scientific investigations, field behavior experiments, and genetic sample collection
https://t.co/Gdp74Onoel
Archived:
https://t.co/ursD2GvzcX
https://t.co/a7M0zwH9YE
Archived:
https://t.co/s1dZlpHu6A
from Guangdong to Yunnan
https://t.co/om0IG3HOBY
Archived:
https://t.co/7HKK59NYq2
Jiao Hengwu, a postdoctoral fellow in Dept of Ecology
https://t.co/pC0Oo2u2ta
Archived: Not Yet as a Chinese VPN is needed to access these pages and if a Chinese IP is used, https://t.co/mA4co7ioje is not accessible.
I shit on the great fearwall!
https://t.co/hLrOVzMiga
Archived:
https://t.co/CQhmXRn5ia
Publication:
https://t.co/dEN8tc2NET
Search "Huabin Zhao live bat Wuhan"
Please scan the QR code in the picture to fill in the questionnaire to get more knowledge and eliminate fear.
https://t.co/yqZDuqanQC
Archived: Not worth Archiving
Let's say a few words for the bat!
The authors list is of interest
@gdemaneuf @MonaRahalkar
Zhao Huabin, WHU
Liu Zhen, Kunming Institute of Zoology
Mao Xiuguang,ECNU
Zhou Peng, WIV
Zhang Libiao, GIBR
https://t.co/0BFSzOZOiH
Not Archived Yet
Graduate students from Dept of Ecology appear on CCTV
https://t.co/A5VlvHfvNp
"Xie Huanwang, a 2017 master student of ecology at Wuhan University, combined his rich experience in bat field surgery.."
Video: https://t.co/mQnw0Rg6GI
Authoritarian Logic drummed into Chinese school kids.
Repeat!
"Chinese medicinal bats are all bats of the bat family. Salty and flat"
https://t.co/up9bK9Qq82
Archived: Not Yet
https://t.co/4OQr1k9k0z
Archived:
https://t.co/PXXhnTi8Hn
Treatment of:
carbuncle without head
support poison to drain pus
pain of blowing milk
breast milk failure
fecal poisoning
pus from the ear
scrofula
ant fistulas & small holes
qi, hemorrhoids, pus & blood
ringworm of the throat
stroke
dysentery, tenesmus
hernia and bladder pain
women's yin and decadence, as hard as an egg: pangolin five dollars. Stir-fried with sand as the end
Treatment of acne blackening
A bat's self-report in the circle of friends:
don't eat game anymore!
https://t.co/yLAV99gZGP
https://t.co/pC0Oo2u2ta
https://t.co/hLrOVzMiga
https://t.co/yqZDuqanQC
https://t.co/0BFSzOZOiH
https://t.co/A5VlvHfvNp
https://t.co/up9bK9Qq82
https://t.co/4OQr1k9k0z
https://t.co/yLAV99gZGP
Huabin Zhao's Lab at Wuhan University
https://t.co/qun6TvLrFi
Unable to download:
https://t.co/PIjDaJgNPD
unroll @threadreaderapp
Research Profile
https://t.co/6gXOcmYLJT
Archived:
https://t.co/rL7gWS7nVJ
Researchers
https://t.co/F5hYw6Yo8N
Archived:
https://t.co/GTPHaW4otX
Publication Page
https://t.co/n8LGklGYr4
Archived
https://t.co/o7qABGuahA
Relevant Journals
https://t.co/o8MihfZNnW
Archived:
https://t.co/p6V8mETPXL
Evolutionary mechanism of the bat sensory system
https://t.co/Exa7g09qpO
Paper
https://t.co/ck3hQQlpyG
differentiation of taste function
https://t.co/8v3FOgLyuj
Food alteration genes (bats)
https://t.co/4c3mBMYY0W
https://t.co/JPyQava5b0
Professor Stephen Rossiter (Queen Mary- London) and Peng Zhou (WIV)
Please follow the WeChat public account: our ecology
https://t.co/Aa2jscV7PG
In praise of bats (In praise of bats. 2017)
https://t.co/01e2YaavUm
Think of bats & SARS again? Let's say a few words for the bat Author: 5 bats Blessings
https://t.co/hom3UeTWFs
unique innate defense-tolerance system in bats
https://t.co/lTQbuJBld1
Linfa Wang
https://t.co/iETxubclWM
More from Billy Bostickson 🏴👁&👁 🆓
1/x Fort Detrick History
Mr. Patrick, one of the chief scientists at the Army Biological Warfare Laboratories at Fort Detrick in Frederick, Md., held five classified US patents for the process of weaponizing anthrax.
2/x
Under Mr. Patrick’s direction, scientists at Fort Detrick developed a tularemia agent that, if disseminated by airplane, could cause casualties & sickness over 1000s mi². In a 10,000 mi² range, it had 90% casualty rate & 50% fatality rate
3/x His team explored Q fever, plague, & Venezuelan equine encephalitis, testing more than 20 anthrax strains to discern most lethal variety. Fort Detrick scientists used aerosol spray systems inside fountain pens, walking sticks, light bulbs, & even in 1953 Mercury exhaust pipes
4/x After retiring in 1986, Mr. Patrick remained one of the world’s foremost specialists on biological warfare & was a consultant to the CIA, FBI, & US military. He debriefed Soviet defector Ken Alibek, the deputy chief of the Soviet biowarfare program
https://t.co/sHqSaTSqtB
5/x Back in Time
In 1949 the Army created a small team of chemists at "Camp Detrick" called Special Operations Division. Its assignment was to find military uses for toxic bacteria. The coercive use of toxins was a new field, which fascinated Allen Dulles, later head of the CIA
Mr. Patrick, one of the chief scientists at the Army Biological Warfare Laboratories at Fort Detrick in Frederick, Md., held five classified US patents for the process of weaponizing anthrax.
2/x
Under Mr. Patrick’s direction, scientists at Fort Detrick developed a tularemia agent that, if disseminated by airplane, could cause casualties & sickness over 1000s mi². In a 10,000 mi² range, it had 90% casualty rate & 50% fatality rate
3/x His team explored Q fever, plague, & Venezuelan equine encephalitis, testing more than 20 anthrax strains to discern most lethal variety. Fort Detrick scientists used aerosol spray systems inside fountain pens, walking sticks, light bulbs, & even in 1953 Mercury exhaust pipes
4/x After retiring in 1986, Mr. Patrick remained one of the world’s foremost specialists on biological warfare & was a consultant to the CIA, FBI, & US military. He debriefed Soviet defector Ken Alibek, the deputy chief of the Soviet biowarfare program
https://t.co/sHqSaTSqtB
5/x Back in Time
In 1949 the Army created a small team of chemists at "Camp Detrick" called Special Operations Division. Its assignment was to find military uses for toxic bacteria. The coercive use of toxins was a new field, which fascinated Allen Dulles, later head of the CIA
1. WIV Research groups (archived pages) for Reference
dsRNA viruses molecular biology
https://t.co/lwrQoo6ygG
2. Emerging Viruses Group
https://t.co/ND56gVGOAn
3. Structural Biology of Viral Genome Replication
https://t.co/wUqc0YIP3X
4. Molecular Biology of hepatitis Viruses & Gene Therapy
https://t.co/snBbxkhNsC
5. Insect Virus Genetic Engineering Lab
https://t.co/S68mVOA2Ob
dsRNA viruses molecular biology
https://t.co/lwrQoo6ygG
2. Emerging Viruses Group
https://t.co/ND56gVGOAn
3. Structural Biology of Viral Genome Replication
https://t.co/wUqc0YIP3X
4. Molecular Biology of hepatitis Viruses & Gene Therapy
https://t.co/snBbxkhNsC
5. Insect Virus Genetic Engineering Lab
https://t.co/S68mVOA2Ob
Keep dwelling on this:
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
Meat is high in Glycosaminoglycans
(central to coronavirus's ability to attach to host cells)
Beef, pork poultry, seafood are rich in heparan sulfate (glycosaminoglycans), highly charged anchors for SARSCoV2
Meat surfaces critical factors for transmission
https://t.co/yP6lH22OTF
1/5 Science behind that tweet just in case anyone thinks I speak without awareness ;)
Glycosaminoglycans from fresh water fish processing discard - Isolation, structural characterization, and osteogenic activity
https://t.co/fyjac03IuV
SALMON MOUTHS
2/5 Salmon Mouths 2
Characterization of Glycosaminoglycans in Gaping and Intact Connective Tissues of Farmed Atlantic Salmon (Salmo salar) Fillets by Mass
3/5 Why does SARS-COV-2 like meat & seafood?
Glycosaminoglycan binding motif at S1/S2 proteolytic cleavage site on spike glycoprotein may facilitate novel coronavirus (SARS-CoV-2) host cell entry
https://t.co/DpHF1WmxeG
Glycosaminoglycans and
4/5 Glycosaminoglycans
Role of in Infectious Disease
(same authors as above)
https://t.co/3q5dn2Io3Q
Glycosaminoglycans in Infectious Disease
https://t.co/Dep7aJlpLP
Murine Coronavirus with an Extended Host Range Uses Heparan Sulfate as an Entry
(central to coronavirus's ability to attach to host cells)
Beef, pork poultry, seafood are rich in heparan sulfate (glycosaminoglycans), highly charged anchors for SARSCoV2
Meat surfaces critical factors for transmission
https://t.co/yP6lH22OTF
1/5 Science behind that tweet just in case anyone thinks I speak without awareness ;)
Glycosaminoglycans from fresh water fish processing discard - Isolation, structural characterization, and osteogenic activity
https://t.co/fyjac03IuV
SALMON MOUTHS
2/5 Salmon Mouths 2
Characterization of Glycosaminoglycans in Gaping and Intact Connective Tissues of Farmed Atlantic Salmon (Salmo salar) Fillets by Mass
3/5 Why does SARS-COV-2 like meat & seafood?
Glycosaminoglycan binding motif at S1/S2 proteolytic cleavage site on spike glycoprotein may facilitate novel coronavirus (SARS-CoV-2) host cell entry
https://t.co/DpHF1WmxeG
Glycosaminoglycans and
4/5 Glycosaminoglycans
Role of in Infectious Disease
(same authors as above)
https://t.co/3q5dn2Io3Q
Glycosaminoglycans in Infectious Disease
https://t.co/Dep7aJlpLP
Murine Coronavirus with an Extended Host Range Uses Heparan Sulfate as an Entry
More from Science
Hugh Everett's birthday! Pioneer of the Many-Worlds Interpretation of quantum mechanics. Let us celebrate by thinking about ontological extravagance. I will do so by way of analogy, because I have found that everyone loves analogies and nobody ever willfully misconstrues them.
We look at the night sky and see photons arriving to us, emitted by distant stars. Let's contrast two different theories about how stars emit photons.
One theory says, we know how stars shine, and our equations predict that they emit photons roughly uniformly in all directions. Call this the "Many-Photons Interpretation" (MPI).
But! Others object. That is *so many photons*. Most of which we don't observe, and can't observe, since they're moving away at the speed of light. It's too ontologically extravagant to posit a huge number of unobservable things!
So they suggest a "Photon Collapse Interpretation." According to this theory, the photons emitted toward us actually exist. But photons that would be emitted in directions we will never observe simply collapse into utter non-existence.
The physicist Hugh Everett III was born #OTD in 1930. His \u201crelative state\u201d formulation of quantum mechanics, which we now call the \u201cMany Worlds Interpretation,\u201d was published in 1957. pic.twitter.com/ZqMsZcPJDG
— Robert McNees, the bastegod (@mcnees) November 11, 2020
We look at the night sky and see photons arriving to us, emitted by distant stars. Let's contrast two different theories about how stars emit photons.
One theory says, we know how stars shine, and our equations predict that they emit photons roughly uniformly in all directions. Call this the "Many-Photons Interpretation" (MPI).
But! Others object. That is *so many photons*. Most of which we don't observe, and can't observe, since they're moving away at the speed of light. It's too ontologically extravagant to posit a huge number of unobservable things!
So they suggest a "Photon Collapse Interpretation." According to this theory, the photons emitted toward us actually exist. But photons that would be emitted in directions we will never observe simply collapse into utter non-existence.
You May Also Like
“We don’t negotiate salaries” is a negotiation tactic.
Always. No, your company is not an exception.
A tactic I don’t appreciate at all because of how unfairly it penalizes low-leverage, junior employees, and those loyal enough not to question it, but that’s negotiation for you after all. Weaponized information asymmetry.
Listen to Aditya
And by the way, you should never be worried that an offer would be withdrawn if you politely negotiate.
I have seen this happen *extremely* rarely, mostly to women, and anyway is a giant red flag. It suggests you probably didn’t want to work there.
You wish there was no negotiating so it would all be more fair? I feel you, but it’s not happening.
Instead, negotiate hard, use your privilege, and then go and share numbers with your underrepresented and underpaid colleagues. […]
Always. No, your company is not an exception.
A tactic I don’t appreciate at all because of how unfairly it penalizes low-leverage, junior employees, and those loyal enough not to question it, but that’s negotiation for you after all. Weaponized information asymmetry.
Listen to Aditya
"we don't negotiate salaries" really means "we'd prefer to negotiate massive signing bonuses and equity grants, but we'll negotiate salary if you REALLY insist" https://t.co/80k7nWAMoK
— Aditya Mukerjee, the Otterrific \U0001f3f3\ufe0f\u200d\U0001f308 (@chimeracoder) December 4, 2018
And by the way, you should never be worried that an offer would be withdrawn if you politely negotiate.
I have seen this happen *extremely* rarely, mostly to women, and anyway is a giant red flag. It suggests you probably didn’t want to work there.
You wish there was no negotiating so it would all be more fair? I feel you, but it’s not happening.
Instead, negotiate hard, use your privilege, and then go and share numbers with your underrepresented and underpaid colleagues. […]
I'm going to do two history threads on Ethiopia, one on its ancient history, one on its modern story (1800 to today). 🇪🇹
I'll begin with the ancient history ... and it goes way back. Because modern humans - and before that, the ancestors of humans - almost certainly originated in Ethiopia. 🇪🇹 (sub-thread):
The first likely historical reference to Ethiopia is ancient Egyptian records of trade expeditions to the "Land of Punt" in search of gold, ebony, ivory, incense, and wild animals, starting in c 2500 BC 🇪🇹
Ethiopians themselves believe that the Queen of Sheba, who visited Israel's King Solomon in the Bible (c 950 BC), came from Ethiopia (not Yemen, as others believe). Here she is meeting Solomon in a stain-glassed window in Addis Ababa's Holy Trinity Church. 🇪🇹
References to the Queen of Sheba are everywhere in Ethiopia. The national airline's frequent flier miles are even called "ShebaMiles". 🇪🇹
I'll begin with the ancient history ... and it goes way back. Because modern humans - and before that, the ancestors of humans - almost certainly originated in Ethiopia. 🇪🇹 (sub-thread):
The famous \u201cLucy\u201d, an early ancestor of modern humans (Australopithecus) that lived 3.2 million years ago, and was discovered in 1974 in Ethiopia, displayed in the national museum in Addis Ababa \U0001f1ea\U0001f1f9 pic.twitter.com/N3oWqk1SW2
— Patrick Chovanec (@prchovanec) November 9, 2018
The first likely historical reference to Ethiopia is ancient Egyptian records of trade expeditions to the "Land of Punt" in search of gold, ebony, ivory, incense, and wild animals, starting in c 2500 BC 🇪🇹
Ethiopians themselves believe that the Queen of Sheba, who visited Israel's King Solomon in the Bible (c 950 BC), came from Ethiopia (not Yemen, as others believe). Here she is meeting Solomon in a stain-glassed window in Addis Ababa's Holy Trinity Church. 🇪🇹
References to the Queen of Sheba are everywhere in Ethiopia. The national airline's frequent flier miles are even called "ShebaMiles". 🇪🇹