BC SOCIETY
Saved by @ThomassRichards

1/ Today has brought a lot of news about 'variants', as we discover community transmission of B.1.351 (SA variant) in the UK.

But some of the people who study these genomes have increasingly started focusing on a different concept: 'constellations', which may be more useful.

 2/ We're actually all using 'variant' wrong anyway – we're using it to refer to a 'lineage'. A lineage is a set of viruses descended from a common ancestor. All B.1.1.7 (UK variant) viruses descend from an infection that probably occurred in August or September.
3/ But what makes this lineage practically important is that it carries a set of mutations which make it more transmissible.

I.e. we don't really care about the ancestry in itself.
4/ For example, one of the mutations that we think is important to B.1.1.7's faster transmission is called N501Y.
5/ It turns out that a lot of the lineages identified as important recently, in Brazil, South Africa, and the UK, have mutations such as N501Y in common (figure adapted from https://t.co/lpJeW0GGnU)
6/ You can see in the table that the lineage originating in South Africa, and those originating in Brazil, have another mutation, called E484K, in common.
7/ Today PHE's Technical Briefing 5 reveals that a small number of B.1.1.7 (UK lineage) genomes have recently been found which newly carry the E484K mutation, which had previously been seen in these South African and Brazilian lineages.
8/ This shows why thinking about constellations is useful. A 'constellation' is just a set of shared mutations carried by viruses, irrespective of ancestry.
9/ Should we treat B.1.1.7+E484K cases as less concerning than viruses descending from those that originated in South Africa?
10/ We don't know the answer to that one way or another. We don't know to what extent E484K is the key mutation to driving the properties of a lineage, and we don't know how this mutation might interact with other mutations B.1.1.7 carries.
11/ But increasingly, it's going to be important to focus on the mutations that viruses carry, and understanding what effect these have, rather than simply focusing on their ancestry.
12/ From everything we have seen across the continents, E484K seems significant, and we should be very alert to its emergence in another lineage with high transmissibility. (There's every indication that the public health authorities are alert).
13/ Here's some more on constellations: https://t.co/dOzmEG5Vju
(I regret saying the use of 'variant' was 'wrong' above, it's all very fuzzy!)

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Noah Smith
Noah Smith
@Noahpinion
1/People I know on the Right tend to be obsessed with the idea of "crimethink", taboos, and the (supposedly) oppressive, omnipresent enforcement of liberal cultural norms.

Why?

My new theory: A lot of it is guilt.

2/It's true that in some circles - the media, universities, many big corporations - liberal norms *are* enforced to some degree, and the enforcement has probably gotten stronger in recent years.

But I don't think this explains all of the Right's obsession.

3/The stereotype is that people on the Right tend to be more threat-sensitive. That would help explain the perception that liberal norm-enforcers are lurking everywhere, ready to pounce and anathematize anyone who makes a misstep.

But I don't think that's all of it either.

4/And of course, it's always fun - whether you're on the Right or the Left, or playing a video game, or whatever - to style yourself as the brave iconoclastic rebel fighting against the oppressive forces of blah blah blah.

But I don't think this is all of it, either.

5/The reason I think it's more than these things is that even *in private*, people on the Right express their "crimethink" ideas very gingerly and hesitantly.

I get the sense that they're not just afraid of external censure, but have also internalized liberal norms.
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Kate Julian
Kate Julian
@katejulian
1/ Something strange is happening with people’s sex lives. 20-somethings are having sex later and less frequently than previous generations. I spent several months digging into this for @theatlantic. https://t.co/5ehzmWY9wi


2/ This phenomenon—I’m calling it a Sex Recession—really surprised me. It seemed improbable in the age of Tinder, digital porn, and attitudes that are generally permissive and sex-positive.

3/ What’s happening isn’t exclusively American: Similar trends are being observed in other countries, including Japan, Australia, the U.K., Finland, and the Netherlands.


4/ One cause is obvious: Adults under 35 are less likely to be living with a partner than in recent decades, and more likely to be living with their parents—which, it’s safe to say, isn’t great for one’s sex life.

5/ But I also found other explanations, each with profound implications. The first, unsurprisingly, has to do with internet enticements. Netflix and other online entertainment may be substituting for sex.
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The Sharing Scientist
The Sharing Scientist
@ScienceShared
Unless we pass laws which support people to enable them to self-isolate properly, any improvements to test & trace will have marginal impact and cases will simply spiral out of control once again as we ease lockdown in December.

A short thread on what we can do and why 👇
1/


Improving the currently poor rates of self-isolation is actually the key point, which many scientists, politicians, & commentators do still seem to be missing.

This requires good public health communication, proper support for those who need to self-isolate, & trust.
2/

Massive testing and tracing will only significantly reduce
transmission if positive cases isolate effectively. Yet
currently fewer than 20% of those who should isolate are fully adherent.

I don't think I need to explain why it's so critical to improve these rates.

3/

Survey data shows intention to adhere to test/trace/isolate behaviours is higher than self-reported adherence: whilst 76% of people intend to share contacts, only 50% of people correctly recognise symptoms &
just 12% get a test, 18% isolate, & 11% of contacts isolate properly.
4

Self-reported ability to self-isolate
is three times lower in those who earn less than £20,000 per year or have less than £100 saved.

5/
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Deepti Gurdasani
Deepti Gurdasani
@dgurdasani1
Brief thread to debunk the repeated claims we hear about transmission not happening 'within school walls', infection in school children being 'a reflection of infection from the community', and 'primary school children less likely to get infected and contribute to transmission'.

I've heard a lot of scientists claim these three - including most recently the chief advisor to the CDC, where the claim that most transmission doesn't happen within the walls of schools. There is strong evidence to rebut this claim. Let's look at


Let's look at the trends of infection in different age groups in England first- as reported by the ONS. Being a random survey of infection in the community, this doesn't suffer from the biases of symptom-based testing, particularly important in children who are often asymptomatic

A few things to note:
1. The infection rates among primary & secondary school children closely follow school openings, closures & levels of attendance. E.g. We see a dip in infections following Oct half-term, followed by a rise after school reopening.


We see steep drops in both primary & secondary school groups after end of term (18th December), but these drops plateau out in primary school children, where attendance has been >20% after re-opening in January (by contrast with 2ndary schools where this is ~5%).
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BIG DADDY
BIG DADDY
@bigdaddyvinz
If you often procrastinate, open this

Stop being a perfectionist.

The root of procrastination for most people ain't laziness, it's anxiety.

I know your anxiety will tell you the worst case scenario. It’s a damn liar.

If you're a procrastinator, you will find every excuse not to do what u need to do. But here's an advice: DO IT FIRST, I call it reverse procrastination.
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Alex Oluwatobi
Alex Oluwatobi
@alexlobaloba
According to psychologists, there are four types of intelligence:

- Intelligence Quotient (IQ)
- Emotional Quotient (EQ)
- Social Quotient (SQ)
- Adversity Quotient (AQ)

1. IQ is the measure of one's ability to comprehend, solve maths; memorize things & recall subject matters.

2. EQ is the measure of your ability to maintain peace with others; keep to time; be responsible; be honest; respect boundaries; be humble, genuine, and considerate.

3. SQ is the measure of one's ability to build a network of friends & maintain it over a long period of time.

4. AQ is the measure of your ability to go through a rough patch in life and come out without losing your mind. It is a new paradigm and can be used to determine who will give up in face of troubles and may abandon their families.

Now to the very interesting & analytical part👇

People that have higher EQ & SQ tend to go further in life than those with high IQ but low EQ &SQ.

Most schools capitalize on improving IQ level while EQ & SQ are played down.

A man of high IQ can end up being employed by a man of high EQ & SQ even though he has an average IQ.

Your EQ represents your character; your SQ represents your charisma. Give in to habits that will improve these three Qs but more especially your EQ and SQ.

EQ and SQ make one manage better than the other.

Try not only to have a higher IQ but also to have higher EQ and SQ.
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V\u0936\u0941\u0926\u094d\u0927\u093f
Vशुद्धि...
@V_Shuddhi
क्या आप जानते हैं कि क्या है, पितृ पक्ष में कौवे को खाना देने के पीछे का वैज्ञानिक कारण!

श्राद्ध पक्ष में कौओं का बड़ा ही महत्व है। कहते है कौआ यम का प्रतीक है, यदि आपके हाथों दिया गया भोजन ग्रहण कर ले, तो ऐसा माना जाता है कि पितरों की कृपा आपके ऊपर है और वे आपसे ख़ुश है।


कुछ लोग कहते हैं की व्यक्ति मरकर सबसे पहले कौवे के रूप में जन्म लेता है और उसे खाना खिलाने से वह भोजन पितरों को मिलता है

शायद हम सबने अपने घर के किसी बड़े बुज़ुर्ग, किसी पंडित या ज्योतिषाचार्य से ये सुना होगा। वे अनगिनत किस्से सुनाएंगे, कहेंगे बड़े बुज़ुर्ग कह गए इसीलिए ऐसा करना

शायद ही हमें कोई इसके पीछे का वैज्ञानिक कारण बता सके।

हमारे ऋषि मुनि और पौराणिक काल में रहने वाले लोग मुर्ख नहीं थे! कभी सोचियेगा कौवों को पितृ पक्ष में खिलाई खीर हमारे पूर्वजों तक कैसे पहुंचेगी?

हमारे ऋषि मुनि विद्वान थे, वे जो बात करते या कहते थे उसके पीछे कोई न कोई वैज्ञानिक कारण छुपा होता था।

एक बहुत रोचक तथ्य है पितृ पक्ष, भादो( भाद्रपद) प्रकृति और काक के बीच।

एक बात जो कह सकते कि हम सब ने स्वतः उग आये पीपल या बरगद का पेड़/ पौधा किसी न किसी दीवार, पुरानी

इमारत, पर्वत या अट्टालिकाओं पर ज़रूर देखा होगा। देखा है न?

ज़रा सोचिये पीपल या बरगद की बीज कैसे पहुंचे होंगे वहाँ तक? इनके बीज इतने हल्के भी नहीं होते के हवा उन्हें उड़ाके ले जा सके।
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Khatvaanga
Khatvaanga
@khatvaanga
Sri Gurubhyo Namah.
Some tweets on Adi Shankaracharya and in particular the Guru Parampara of @sringerimath. [I had done this series earlier 5 years ago on account of Shishya Sweekaram].


Adi Shankara established the Sringeri Peetham as the 1st of 4 amnaaya peetams.

The four being
1. Sarada Peetam at Sringeri.
2. Govardhana Peetam at Puri
3. Kalika at Dwaraka
4. Jyothir at Badarikashramam.

He installed his 4 most prominent shishyas as heads of the peetams.

Sureshwaracharya was assigned to Sringeri as its head.

Sringeri is a corruption of Rshyashrunga giri.

Rshyashrunga maharshi [and his father Sri Vibandhaka Maharshi] did their tapas at this place.

It is at Sringeri that Shankara spent 12 of His precious 32 years!!

That gives you and idea how much He loved this place.

Rshyashruga maharshi had a horn on his forehead, a result of being born to a deer. His mere presence was enough to shower rains!!

Rshyashrunga was one who led Putrakamesthi Yaagam of Dasaratha Maharaj and which resulted in Sri Rama's birth!!
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Vibhu Vashisth
Vibhu Vashisth
@VIBHU_Tweet
प्राचीन काल में गाधि नामक एक राजा थे।उनकी सत्यवती नाम की एक पुत्री थी।राजा गाधि ने अपनी पुत्री का विवाह महर्षि भृगु के पुत्र से करवा दिया।महर्षि भृगु इस विवाह से बहुत प्रसन्न हुए और उन्होने अपनी पुत्रवधु को आशीर्वाद देकर उसे कोई भी वर मांगने को कहा।


सत्यवती ने महर्षि भृगु से अपने तथा अपनी माता के लिए पुत्र का वरदान मांगा।ये जानकर महर्षि भृगु ने यज्ञ किया और तत्पश्चात सत्यवती और उसकी माता को अलग-अलग प्रकार के दो चरू (यज्ञ के लिए पकाया हुआ अन्न) दिए और कहा कि ऋतु स्नान के बाद तुम्हारी माता पुत्र की इच्छा लेकर पीपल का आलिंगन...

...करें और तुम भी पुत्र की इच्छा लेकर गूलर वृक्ष का आलिंगन करना। आलिंगन करने के बाद चरू का सेवन करना, इससे तुम दोनो को पुत्र प्राप्ति होगी।परंतु मां बेटी के चरू आपस में बदल जाते हैं और ये महर्षि भृगु अपनी दिव्य दृष्टि से देख लेते हैं।

भृगु ऋषि सत्यवती से कहते हैं,"पुत्री तुम्हारा और तुम्हारी माता ने एक दुसरे के चरू खा लिए हैं।इस कारण तुम्हारा पुत्र ब्राह्मण होते हुए भी क्षत्रिय सा आचरण करेगा और तुम्हारी माता का पुत्र क्षत्रिय होकर भी ब्राह्मण सा आचरण करेगा।"
इस पर सत्यवती ने भृगु ऋषि से बड़ी विनती की।


सत्यवती ने कहा,"मुझे आशीर्वाद दें कि मेरा पुत्र ब्राह्मण सा ही आचरण करे।"तब महर्षि ने उसे ये आशीर्वाद दे दिया कि उसका पुत्र ब्राह्मण सा ही आचरण करेगा किन्तु उसका पौत्र क्षत्रियों सा व्यवहार करेगा। सत्यवती का एक पुत्र हुआ जिसका नाम जम्दाग्नि था जो सप्त ऋषियों में से एक हैं।
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Vedic Gyaan
Vedic Gyaan
@vedicgyaanindia
The chorus of this song uses the shlokas taken from Sundarkand of Ramayana.

It is a series of Sanskrit shlokas recited by Jambavant to Hanuman to remind Him of his true potential.

1. धीवर प्रसार शौर्य भरा: The brave persevering one, your bravery is taking you forward.


2. उतसारा स्थिरा घम्भीरा: The one who is leaping higher and higher, who is firm and stable and seriously determined.

3. ुग्रामा असामा शौर्या भावा: He is strong, and without an equal in the ability/mentality to fight

4. रौद्रमा नवा भीतिर्मा: His anger will cause new fears in his foes.

5.विजिटरीपुरु धीरधारा, कलोथरा शिखरा कठोरा: This is a complex expression seen only in Indic language poetry. The poet is stating that Shivudu is experiencing the intensity of climbing a tough peak, and likening

it to the feeling in a hard battle, when you see your enemy defeated, and blood flowing like a rivulet. This is classical Veera rasa.

6.कुलकु थारथिलीथा गम्भीरा, जाया विराट वीरा: His rough body itself is like a sharp weapon (because he is determined to win). Hail this complete

hero of the world.

7.विलयगागनथाला भिकारा, गरज्जद्धरा गारा: The hero is destructive in the air/sky as well (because he can leap at an enemy from a great height). He can defeat the enemy (simply) with his fearsome roar of war.
VEDICGYAN