HOW TO STAY YOUNG:

Starve-destroy-recycle-eat-build-eat-build-starve...

The human ecosystem (our internal environment) has the same processes as the environmental ecosystem. Destruction & Reconstruction is a universal process. This is how we stay young.

We should take our cue from the senolytic processes of nature. A coppiced Hazel tree is near immortal.
Too much destruction (chronic calorie restriction) and too much growth (hyperfunction/ constant eating) are both bad and lead to derangement.
'A single bout of resistance training induced rapid clearance of senescent cells in muscle' h/t @Mangan150

https://t.co/MW7oFn6bgm
"Conc: Rapid senescent cell clearance of human skeletal muscle during resistance exercise seems to associate with enhanced in situ phagocytosis. High protein availability accelerates resolution of muscle inflammation and promotes muscle increment after training" h/t @SPKP1124
After Resistance or High-Intensity training I sometimes eat directly after (with sufficient protein) but very often don't eat for a couple hours as I want to continue the 'destruction' process.
Physical Standards. Note: These all involve intensity without killing yourself.
FASTING - Why it works.

1 The brain ‘improves’ in response to hunger;

2 The body preserves itself in response to deprivation.

Seen as an evolutionary survival mechanism the fasting rationale becomes clear.

https://t.co/DTKkLkLGMc
Summary:

You have to recycle your body. Just like the environment recycles itself.

Hard exercise (on top of a good aerobic base/gen activity) but no need to overtrain. Work-out fasted (50% of time), eat 18/6, 2 meals a day, default is slight CR, + overfeeding once/twice a week

More from Science

An interesting thing about carp is that they can go into anoxic hibernation and switch to an anaerobic metabolism based on converting glycogen to ethanol.

The waste ethanol is diffused out the gills

https://t.co/V3D1umHf04

Carp can switch over to an anaerobic metabolism and quietly exhale booze until the situation gets better.

They basically evolved the same metabolic pathway as yeast, independently.

In theory, if you spent a few thousand years breeding carp for it, you could use them to make booze.

They'd be enormous, almost entirely glycogen deposits with a fish added as an afterthought.

The really interesting thing about anaerobic carp, is that they can go 4-5 months without oxygen by relying on liver glycogen.

You, a human, have only about 100 grams of glycogen in your liver, about 400 more grams in your skeletal muscles. Call it 500 grams total.

In humans, glycogen is also burned for energy. This is where the marathon runner's bonk comes from: you only have about 2,000 calories worth, and running a marathon burns those 2,000 calories.
This is a thread on statistics in science: 1/7 (via @LogicofScience)

Basic Statistics Part 1: The Law of Large Numbers https://t.co/wUH8eAAIak

#Science #Statistics


Basic Statistics Part 2: Correlation vs. Causation

https://t.co/Azhyl8pDsX (2/7)

Basic Statistics Part 3: The Dangers of Large Data Sets: A Tale of P values, Error Rates, and Bonferroni Corrections

https://t.co/LetN6aEBRM (3/7)

Basic statistics part 4: understanding P values

https://t.co/K8MMMgTCOf (4/7)

Basic Statistics Part 5: Means vs Medians, Is the “Average”

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