BC HEALTH
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I know some people who seem (to me) more concerned with receiving VALIDATION for their mental health issues than solving them.

They seem to care most about other people BELIEVING their problems are real.

I'm curious about this.

 Like, it's more important to them that people know how debilitating their anxiety is, than to overcome the anxiety.

Or it's important to them that others believe that they're actually depressed, not "just sad."
Or they want people buy into the narrative that they've been traumatized, and might be something like offended if someone minimizes that.
What do we make of this?
1. One possibility is that if solving the problems seems hopeless or even just really hard, you need external support to be able to cope.

If no one cuts you slack because of your mental health stuff, maybe you're in a really bad place, so you need people to believe you.
(Though of course, just like any time you set up system that will grant resources to someone on the basis of a signal, there's now an incentive to fake the signal.
I'm sure there are people who are fooling themselves about how bad their mental problems are as a way to buy that slack for themselves.)
2. In some cases there is more at stake than simply getting slack in order to function. If you can claim to have been "traumatized" or "abused" (in a way that will be believed), you can use that to marshal political support,
because "abuse" like "racism" is loaded word that points out something that contemporary culture has coordinated to oppose heavily.

https://t.co/07v275i2gt
(A recent example of this is the AOC video about the capital attack.

While she said some things I agree with, I rolled by eyes at her use of the word "trauma" because it seemed to me a transparent way to show political support to folks who's trauma narratives are important to...
them, while simultaneously making a social attack on the other side, by claiming to have been harmed "a lot" by them.)

I guess there's a general thing here: the more you can claim to have been harmed, the more likely people are to rally to support you.
So, if someone is denying that you were traumatized, that's threatening, because they're making a move to take away the foundation of your social power.
3. Another tact: Assuming _I_ was engaging in this kind of behavior, what would be happening for me?

I was once in a social dynamic where I would construct things such that I was visibly sad or put upon, because that was the only way I knew to revive (a type of) affection.
So one plausible story is that the ONLY way that a person knows how to get sympathy (or maybe some particular kind of sympathy) is by dint of their mental health stuff.

They need it, and they need it to be believed, because that's the only way they can feel loved and supported.
4. Maybe the simplest story is that this doesn't have anything to do with mental health stuff, in particular. People just have a need to have their narratives validated, and this is just one special case of that.

(Though that begs the question of WHY people have that need.)
Notably, it seems that the mechanism of most therapy is "a prestigious person gives you attention for a while, validating that your problems / experience is real.
5. A more specific version of the above hypothesis is that people feel a latent shame about their mental health stuff, because some part of them thinks it is personal weakness.
But if the establishment certifies them as having a medical condition, or they otherwise construct a narrative about how this is a thing that is happening to them instead of a thing that they are doing, then they have a kind of security from blame and/or shame.
But if someone doubts that narrative, the latent shame comes roaring back, and so they feel threatened.
5.5. Another flavor of this basic idea:

The establishment certifies that this problem is HARD, you're not expected to just be able to trivially solve it. Which gives one protection against others' claims (or even demands) that you can and should.
(Which, surprisingly, seems to be almost a reformulation of my first hypothesis.)
Are other people familiar with this phenomenon, either in yourself, or in other people?

Do you have a story for what's going on?
(All of this was almost definitely influenced by and exchange with @HiFromMichaelV, plus some other stuff.)

More from Eli Tyre

Eli Tyre
Eli Tyre
@EpistemicHope
I was reading something that suggested that trauma "tries" to spread itself. ie that the reason why intergenerational trauma is a thing is that the traumatized part in a parent will take action to recreate that trauma in the child.

This model puts the emphasis on the the parent's side: the trauma is actively "trying" to spread.

This is in contrast to my previous (hypothetical) model for IGT, which puts the emphasis on the child's side: kids are sponges that are absorbing huge amounts of info, including via very subtle channels. So they learn the unconscious reactions of the people around them.

(I say "hypothetical", because all while this sort of thing is in my hypothesis space, I haven't seen clear enough evidence that intergenerational trauma is a meaningful category that I solidly believe it is real.

More like, "here's a story for how this could work.")

On first glance, I was skeptical of this "active trauma" story.

Why on earth would trauma be agenty, in that way? It sounds like too much to swallow.
CULTURE
Eli Tyre
Eli Tyre
@EpistemicHope
My catch all thread for this discussion of AI risk in relation to Critical Rationalism, to summarize what's happened so far and how to go forward, from here.

I started by simply stating that I thought that the arguments that I had heard so far don't hold up, and seeing if anyone was interested in going into it in depth with


So far, a few people have engaged pretty extensively with me, for instance, scheduling video calls to talk about some of the stuff, or long private chats.

(Links to some of those that are public at the bottom of the thread.)

But in addition to that, there has been a much more sprawling conversation happening on twitter, involving a much larger number of people.

Having talked to a number of people, I then offered a paraphrase of the basic counter that I was hearing from people of the Crit Rat persuasion.
POLITICS
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Eli Tyre
Eli Tyre
@EpistemicHope
CritRats!

I think AI risk is a real existential concern, and I claim that the CritRat counterarguments that I've heard so far (keywords: universality, person, moral knowledge, education, etc.) don't hold up.

Anyone want to hash this out with


For instance, while I heartily agree with lots of what is said in this video, I don't think that the conclusion about how to prevent (the bad kind of) human extinction, with regard to AGI, follows.

There are a number of reasons to think that AGI will be more dangerous than most people are, despite both people and AGIs being qualitatively the same sort of thing (explanatory knowledge-creating entities).

And, I maintain, that because of practical/quantitative (not fundamental/qualitative) differences, the development of AGI / TAI is very likely to destroy the world, by default.

(I'm not clear on exactly how much disagreement there is. In the video above, Deutsch says "Building an AGI with perverse emotions that lead it to immoral actions would be a crime."
SOCIETY
Eli Tyre
Eli Tyre
@EpistemicHope
There's a particular kind of romantic partnership, with a certain sort of person, that I've wanted since I became a self-aware, directed agent at around age 15.

Empirically, this kind of relationship has been hard to achieve. It hasn't worked out yet, at least.

And this sometimes leaves me wondering if my standards are unreasonable.

In years past that desire was often very alive.

These days, I'm rarely directly or viscerally in contact with it.

I sometimes contemplate aiming for some other kind of romantic and/or sexual relationship instead. In part because I might be more effective if I...I don't know, got laid more? But that's not really the thing. More like, if I had someone around whom I could regularly relax.

But mostly, I don't pursue those alternative relationship-setups out of a sense of something like loyalty to myself + a vague sense of wrongness and/or sadness about it. It often feels like giving up or giving in.

[I might elaborate on the wrongness sometime.]
FOR LATER READ
Eli Tyre
Eli Tyre
@EpistemicHope
@JeffLadish I think because the reward structure of being a bio-ethicist rewards saying level-headed sounding, cautious-sounding, conventional wisdom?

Though I'm not sure why that is.

I guess if you want to radically improve the world, you mostly don't go into a field that is about opining on other people's work, you go into something like Engineering and do the work?

I note that Nick Bostrom is what a Bioethicist should be: he thinks hard about tradeoffs and risks, and crystalizes concepts like the Unilateralist's curse and black ball technologies.

But this is starting from a place of "The world could be vastly better. How do we get there?"

I don't know why bioethics doesn't look more like a field of (less smart) Bostroms.

I guess because everyone's disgust reactions are triggered by the actually good proposals, and in order to make those proposals the consensus of the field a lot of people have to bite the bullet and stick their neck out saying "I know this sounds crazy / absurd / vaguely evil...
SOCIETY

More from Health

Tony Breu
Tony Breu
@tony_breu
1/16
Why do B12 and folate deficiencies lead to HUGE red blood cells?

And, if the issue is DNA synthesis, why are red blood cells (which don't have DNA) the key cell line affected?

For answers, we'll have to go back a few billion years.


2/
RNA came first. Then, ~3-4 billion years ago, DNA emerged.

Among their differences:
🔹RNA contains uracil
🔹DNA contains thymine

But why does DNA contains thymine (T) instead of uracil (U)?

https://t.co/XlxT6cLLXg


3/
🔑Cytosine (C) can undergo spontaneous deamination to uracil (U).

In the RNA world, this meant that U could appear intensionally or unintentionally. This is clearly problematic. How can you repair RNA when you can't tell if something is an error?

https://t.co/bIZGviHBUc


4/
DNA's use of T instead of U means that spontaneous C → U deamination can be corrected without worry that an intentional U is being removed.

DNA requires greater stability than RNA so the transition to a thymine-based structure was beneficial.

https://t.co/bIZGviHBUc


5/
Let's return to megaloblastic anemia secondary to B12 or folate deficiency.

When either is severely deficient deoxythymidine monophosphate (dTMP*) production is hindered. With less dTMP, DNA synthesis is abnormal.

[*Note: thymine is the base in dTMP]

https://t.co/AnDUtKkbZh
HEALTH , PATHOPHYSIO
lazy perfectionist
lazy perfectionist
@kazADHD
is ADHD a mental illness ?

a thread

ADHD is a neurodevelopmental disorder - people with it are born with it and it cannot be altered because it's part of their brain structure and is seen on brain scans. ADHD is also linked to premature births and hypothyroidism during pregnancy, among other things

from the WHO website: "neurodevelopmental disorders are disabilities in the functioning of the brain that can affect behaviour, memory and/or ability to learn."

neurodevelopmental disorders are not caused by external/environmental factors. you cannot *develop* these conditions

mental illness is a general term for a health problem that significantly affects how someone feels/thinks/behaves. mental illnesses cause suffering to those who experience them, as well as often their loved ones. ADHD does not directly cause suffering.

neurodevelopmental disorders are not mental illnesses. ADHD however, does make it more likely for a person to experience mental illness. ADHD can cause dysfunction and stress, but more often than not this comes from lack of accommodation rather than the symptoms themselves.
HEALTH
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Cam Patterson
Cam Patterson
@drcampatterson
UAMS has taken the extraordinary step of asking leadership across our health system to refrain from traveling over the coming holidays and report to work or be available if needed. Other hospitals in our state are considering similar measures.

(1)

Although the health care system in the state of Arkansas is stressed right now, it is holding up, and additional surge capacity exists. But that capacity is not infinite.  Every day, we become more and more concerned about our ability to manage what lies ahead.

(2)

As health professionals, we are doing all we can. However, one thing is certain. We can’t meet this challenge unless you are with us. As Secretary Jose Romero of the AR Dept. of Health has said, we are in the midst of a “surge within a surge” in this COVID-19 pandemic.

(3)

Right now, the @UAMS_COPH COVID-19 forecasts, which have been strikingly accurate so far, indicate that the density of COVID-19 infections exceeds each of our abilities—yours & mine -- to avoid contact with actively infected individuals in our state...

(4)

...whenever we venture outside our homes. They predict an exponential increase in coronavirus deaths in the next two weeks, more than we saw in the first four months of the pandemic. We may soon exceed the number of beds, ventilators, & most importantly...

(5)
HEALTH
Matthias Deutsch
Matthias Deutsch
@Ma_Deutsch
No-regret #hydrogen:
Charting early steps for H₂ infrastructure in Europe.

👉Summary of conclusions of a new study by @AgoraEW @AFRY_global @Ma_Deutsch @gnievchenko (1/17)
https://t.co/YA50FA57Em


The idea behind this study is that future hydrogen demand is highly uncertain and we don’t want to spend tens of billions of euros to repurpose a network which won’t be needed. For instance, hydrogen in ground transport is a hotly debated topic https://t.co/RlnqDYVzpr (2/17)

Similar things can be said about heat. 40% of today’s industrial natural gas use in the EU goes to heat below 100°C and therefore is within range of electric heat pumps – whose performance factors far exceed 100%. (3/17)


Even for higher temperatures, a range of power-to-heat (PtH) options can be more energy-efficient than hydrogen and should be considered first. Available PtH technologies can cover all temperature levels needed in industrial production (e.g. electric arc furnace: 3500°C). (4/17)


In our view, hydrogen use for feedstock and chemical reactions is the only inescapable source of industrial hydrogen demand in Europe that does not lend itself to electrification. Examples include ammonia, steel, and petrochemical industries. (5/17)
HEALTH
Avraham Z. Cooper, MD
Avraham Z. Cooper, MD
@AvrahamCooperMD
1/15
Why can cefepime cause neurological toxicity?

And why is renal failure the main risk factor for this complication?

The answer requires us to learn about cefepime's structure and why it unexpectedly binds to a certain CNS receptor.

#MedTwitter #Tweetorial


2/
Let's establish a few facts about cefepime:

🔺4th generation cephalosporin antibiotic
🔺Excretion = exclusively in the urine (mostly as unchanged drug)
🔺Readily crosses the blood-brain barrier (so it easily accesses the brain)

https://t.co/rjYG1BfGPR


3/
The first report of cefepime neurotoxicity was in 1999.

A patient w/ renal failure received high doses of cefepime and then developed encephalopathy, tremors, myoclonic jerks, and tonic-clonic seizures.

✅All symptoms resolved after hemodialysis.

https://t.co/u7JLVitQpp


4/
Cefepime neurotoxicity is surprisingly common, occurring in up to 15% of treated critically ill patients (w/ symptoms varying from encephalopathy to seizures).

💡The main risk factors = renal failure and lack of dose adjustment for renal function.

https://t.co/nxbnzSq8AR


5/
What about cefepime induces neurotoxicity?

One clue is that it's not the only antibiotic that causes neurotoxicity, particularly seizures.

This actually is a class effect w/ other beta-lactam antibiotics (including penicillins and carbapenems).

https://t.co/Lf4BhON9IY
HEALTH

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महर्षि कश्यप की तेरह पत्नियां थीं।लेकिन विनता व कद्रु नामक अपनी दो पत्नियों से उन्हे विशेष लगाव था।एक दिन महर्षि आनन्दभाव में बैठे थे कि तभी वे दोनों उनके समीप आकर उनके पैर दबाने लगी।


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कद्रू बोली,"स्वामी! मेरी इच्छा है कि मैं हज़ार पुत्रों की मां बनूंगी।"
विनता बोली,"स्वामी! मुझे केवल एक पुत्र की मां बनना है जो इतना बलवान हो की कद्रू के हज़ार पुत्रों पर भारी पड़े।"
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महर्षि ने यज्ञ किया,विनता व कद्रू को आशीर्वाद देकर तपस्या करने चले गए। कुछ काल पश्चात कद्रू ने हज़ार अंडों से काले सर्पों को जन्म दिया व विनता ने एक अंडे से तेजस्वी बालक को जन्म दिया जिसका नाम गरूड़ रखा।जैसे जैसे समय बीता गरुड़ बलवान होता गया और कद्रू के पुत्रों पर भारी पड़ने लगा


परिणामस्वरूप दिन प्रतिदिन कद्रू व विनता के सम्बंधों में कटुता बढ़ती गयी।एकदिन जब दोनो भ्रमण कर रहीं थी तब कद्रू ने दूर खड़े सफेद घोड़े को देख कर कहा,"बता सकती हो विनता!दूर खड़ा वो घोड़ा किस रंग का है?"
विनता बोली,"सफेद रंग का"।
तो कद्रू बोली,"शर्त लगाती हो? इसकी पूँछ तो काली है"।
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*Heads-up that this thread will feature some extreme examples of homophobia and transphobia.*

Hey folks, have you ever wondered why trans people face constant accusations of fetishism, sexual predation and child abuse/grooming? Well, today let's talk about stochastic terrorism.

So, first we have to talk about what stochastic terrorism actually is. Remember when there was a conspiracy that there was a pedophile ring operating out of a pizza parlour basement, and a crazed gunman showed up? It's that sort of incitement that stochastic terrorism describes.

It's the demonisation or incitement against a group of people or individuals with the intent that other, unaffiliated parties will act upon it; it's the releasing doctored footage and a shooter show up at Planned Parenthood as a direct result of what he's been led to believe.

So with that in mind, let's talk about Russia's extreme anti-LGBT laws that banned the "promotion" of LGBT lifestyles to children. A move that specifically marked LGBT people as a threat to children, and resulted in neo-nazis meting out vigilante "justice" against gay men.


Groups such as this would lure unsuspecting gay men via dating sites, and brutalise and humiliate them on camera. They did so under the guise of combating child abusers, one group calling themselves "Occupy
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Sara Benincasa
Sara Benincasa
@SaraJBenincasa
Spent a quaint half hour in a cafe listening to a guy yell at his dad after his dad said that the women Trump molested wanted it: "Dad, that's like saying the Jews who died in the Holocaust were asking for it!" ENJOY YOUR TERRIBLE FAMILIES THIS WEEK!

"Mom, has a man ever touched you without your consent?"
"Of course."
"Did you report it?"
"No."
"Dad, your WIFE has been through this!"

Dad was unmoved and told the guy to stop arguing with him.

At this point we learned the boy child has allergies.

I forgot to remark upon the presence of the very cute grandson, who was very small and gave not one shit about the yelling. I believe a sister or aunt was present and feeling very stressed. I wanted to hand her a Xanax or seven.

It was really hard to not jump in and say, "Sounds like you guys are going to have a fun meal tomorrow!" so they could unite in hatred against me, the outsider, and stop squabbling. Instead I exchanged glances with a nearby fellow lady patron, who also emotionally ate a cookie.

Anyway, I want to thank the random family for yelling about rape and the Holocaust in an Israeli cafe in the US of A today because it reminded me that while this country isn't the greatest, it is inevitably my stupid favorite and I am never, ever bored.
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Suhas S. Hardutt
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@HarduttSuhas
THE BATTLE OF SARAIGHAT (1671)

Lachit Borphukan's humiliation of Aurangzeb.

The battle of Saraighat was a naval engagement fought on the Brahmaputra river near Saraighat between the M0ghul empire and Ahom kingdom in 1671.

Guts, resolve and glory!

(Elaborate thread)


Koch was a state situated between the dominions of M0ghuls and Ahoms. For Ahoms, it was a buffer state for keeping M0ghul territorial expansions at bay.(1)

Times changed when the ruler of the Koch kingdom, Nara Narayana passed away in 1587 resulting in Koch being divided into 2. Western Koch was ruled by his son Lakshmi Narayan and the eastern Koch by his nephew, Raghudev.(2)

Lakshmi Narayan formed an alliance with M0ghuls after which he attacked Parikshit, son of Raghudev, in 1602. Parikshit Narayan was defeated while his brother Bali Narayan took refuge in the Ahom Kingdom.(3)

The M0ghuls used it as a pretext to invade Ahom kingdom. The first battle between them took place in 1615 leading to a series of engagements in which both sides had their shares of ups and downs resulting in a stalemate.(4)
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