3 December 2020 #MAGAanalysis #RedoTheElection

When You Catch A Thief

The sleeping giant of America sleeps no more. We have awakened. We're nothing more than the same Common Sense Americans we were in 1776. We're feisty. Independent and self-sufficient. Hard working.

11 January 2020 #MAGAanalysis #Overturn

Information, Disinformation, And Overwhelm

In these weeks since the election, I feel like I've begun to come to understand the world of intelligence officers and analysts a great deal more than ever before.

10 January 2020 #MAGAanalysis #TheGreat2021Purge

Thou Shalt Not Speak Truth

We begin today's work with a notification I found on @AnnVendersteel's Parler account (under that handle) just now. You'll see, the purge progresses. I quote in full below.

31 December 2020 #MAGAanalysis #Overturn

Comments on @OptimisticCon's Article - Part 3

As I forgot to give the link to the article, yesterday, let's get that covered right

16 January 2021 #MAGAanalysis #Overturn

The Man Who Met Himself

First, I have to again thank @BernadetteMay for the delightful and foretelling new banner photo I stole from her. It is truly profound and hopefully prophetic.

20 January 2021 #MAGAanalysis

The Day After

Here's the link to soon-to-be former President Trump's Farewell Speech. It's not easy watching, I can tell you that. But we boldly do what we must,

#SuvenLife – Niche R&D play..very high risk and very high reward…key is right allocation…

Jazz Pharma was quoting around $0.5 in 2009, today its $150 and Mcap of $8.5 Bn on Nasdaq..almost 300x in 11 years. 80% of its total sales ($2.1 Bn) come from single drug Xyrem.

Axovant Lifescience, bought Alzheimer molecule from GSK, repackaged it and done phase-3 trials. Before starting the trials, the valuation was $2 Bn, just before announcing the data, it rose to $3 Bn. One of the leading broker put the target of $12 Bn if the trials succeeded..

but it failed in phase-3 trials. Current Mcap is $120 Mn…

This is R&D for New Chemical Entity (NCE)…very high risk and very high reward…

Brain-related illnesses, also known as CNS diseases, afflict more than 2 billion people worldwide. Diseases of the brain and mind range

from Alzheimer’s, dementia, epilepsy, migraine, multiple sclerosis, neuro infections, Parkinson’s, psychosis, schizophrenia and stroke to brain injuries and various mental disorders. The global market or CNS therapeutics is projected to reach $137.7 billion by 2025.

#SuvenLife has 1 lead molecule SUVN-G3031 in phase-2 trials which is similar to Xyrem but superior features, 3 molecules completed phase-1 trials and starting phase-2 trials and 11 molecules in pre-clinical trials. All are related to CNS which is growing and uncluttered market

It's a slow, snowy afternoon. How about a 🧵 on "rationalists" & "rationalism"? I want to talk about what real rationalism might look like & what people devoted to rationalism might actually behave like--and how that differs from what you often see from self-styled rationalists.

Caveat up front: this is not about Slate Star Codex, which I haven't read regularly enough to have an opinion on, or about the recent controversy between SSC & the NYT. I'm more interested in the *idea* of rationalism (vs. the practice).

The core premise of rationalism, as I understand it, is simply that humans' cognitive machinery was not designed by evolution to find truth, but rather to advance the interests & welfare of the collective -- a Venn overlap, but not the same thing. Therefore ...

... reasoning well, both individually & as groups, requires special effort. It requires consciously trying to set aside the parochialism, biases, & other distortions that typically characterize our thinking -- resisting, to some extent, the dynamics of group membership/welfare.

That's all fine. I agree entirely that we should make special effort to reason well & to guard against the typical failures of reasoning to which we humans are prone. I believe it's the best (maybe only) way forward as a species. So far so good.

With Myanmar, it seems that some are raising questions about the efficacy of sanctions and concerns about unintended consequences. It’s time for a “Myth and Realities” guide. THREAD. #WhatsHappeningInMyanmar

Myth: Human rights groups are calling for blanket sanctions on Myanmar.
 
Reality: This is false. Most human rights groups are calling for targeted measures directed solely at the military of Myanmar and companies it owns and which give revenue directly to it.

We are talking about the conglomerates and corporations that control the country’s natural resources, including the concessions for extractive sectors (oil and gas, timber, and mining of gemstones, jade, and valuable metals).

We’re calling on governments to focus on revenues and block transactions or seize government or state assets only where there is credible information that the military or its leaders are looting or acquiring state revenues or redirecting it to them.

Myth: Even if tailored narrowly, targeted sanctions will have major negative impacts on the people of Myanmar.
 
Reality: There are all kinds of ways to prevent unintended consequences on the broader Myanmar economy.