More email evidence here:
More Smoking Gun Emails From Kobe University Virologist Teridah Ernala Ginting
Acts Of Espionage Against Indonesia by Akiko Makino and Others From Kobe University's "Secret" Lab
https://t.co/6eLE46pA1A
1. Finally!
I found the original H1N1-H5N1 "novel" viruses emails! Yes!
https://t.co/MoPgxYJIEv
Kawaoka Busted!
More email evidence here:
More Smoking Gun Emails From Kobe University Virologist Teridah Ernala Ginting
Acts Of Espionage Against Indonesia by Akiko Makino and Others From Kobe University's "Secret" Lab
https://t.co/6eLE46pA1A
(where Kawaoka organised theft of viruses)
(Now moved to Phnom Penh)
https://t.co/snRmicOIGN
History:
https://t.co/vEjltSDTOj
Perspectives on the DOD Global Emerging Infections Surveillance System:
GEIS at NAMRU 2, Indonesia (PDF)
https://t.co/SKm22oqBD4
Indonesia Suspends US NAMRU Lab Operations
https://t.co/kLW3zhiDVz
Supari On NAMRU-2
https://t.co/0wPbF4TpTJ
Indonesian Lawmakers Call For NAMRU-2 Probe
https://t.co/S4zZ4TaksW
NAMRU-2 Debate Turns Ugly
https://t.co/O1NbYZAvez
U.S. insists on immunity for all Namru-2 laboratory staff
https://t.co/KelkEqJQTn
A "fact sheet" on NAMRU-2
https://t.co/Z08aLEDIJ4
US Embassy Half Truths:
https://t.co/b0nP0aVIwV
Indonesia: More attacks on NAMRU-2
https://t.co/owYVRjxf7f
US Scientists curses Indonesians:
"A pandemic on both your houses!"
https://t.co/3tDN9sG5RM
US Says Indonesia Stalling On NAMRU-2
https://t.co/6Hrejf2ocP
US-Indonesian debates over bird flu samples involve NAMRU-2
https://t.co/GefodzfHN7
Virus, Namru 2 and the New Minister of Health
(Anti Namru Diatribe)
https://t.co/CgLOULSwS7
13 Tedious Pages of Discussion on NAMRU 2 Controversy:
https://t.co/DUBt4D0TrC
Clarification on NAMRU-2's Status
https://t.co/cmuWM4web9
Wikileaks Classified Cable
https://t.co/YMavlgmzt1
Interesting as it reveals US strategy and motives for involvement in the BSL 3 Program (also applies to China in broad outlines)
Towards effective emerging infectious disease surveillance: Cambodia, Indonesia, & NAMRU-2
Sophal Ear (Naval Postgraduate School) 2011
https://t.co/WNac9XB555
collaboration between the DRTA's Office of Strategic Research & Dialogues & ]Naval Postgraduate School
I am just padding the background about NAMRU 2 before getting back to the main Kawaoka story involving theft and smuggling of viruses to his laboratory in Japan and his GOF work in Japan and the USA.
It's important to paint the whole picture I think.
interview with Indonesiaโs health minister, Siti Fadilah Supari
(scroll down for some interesting comments)
https://t.co/LadScWvAkK
Preparing Indonesia:
H5N1, Foucault and Viral Sovereignty through the Lens of Global Health
https://t.co/bd13dtsjOM
Indonesia & WHOโs new Pandemic Influenza Plan
https://t.co/Opg7hkZNFB
Highly Pathogenic Avian Influenza H5N1 Virus:
a 20-year journey of insecure landscapes
https://t.co/DKvUes3OPA
Pages 117-141: Kawaoka & Fouchier's GOF work on H5N1
H5N1 & "Spanish" Flu Reconstruction of 1918-like avian influenza virus stirs concern over GOF experiments
https://t.co/IUD3CzAUaQ
Scientists condemn 'crazy, dangerous' creation of deadly airborne flu virus
https://t.co/4zJuzvPA8W
E.G:
Ito, Goto, Yamamoto, Tanaka, Takeuchi, Kuwayama, Kawaoka, Otsuki (a Tongue Twister ;)
Generation of a Highly Pathogenic Avian Influenza A Virus From an a virulent Field Isolate by Passaging in Chickens.
I am certainly not going to trawl through all 700 or so papers here under the name Kawaoka:
https://t.co/LSpUKMksHr
But you can, if you like?
A useful discussion here:
Virologists plan influenza H7N9 GOF experiments (2013)
https://t.co/JBS1UjluYb
The Letter (GOF experiments on H7N9
Fouchier, Kawaoka & 20 co-authors
https://t.co/u6ifRnXmhq
https://t.co/vNlqAVIjK3
Make of the names what you will, perhaps you recognise some of them?
Vincent Racaniello, the Propaganda Chief of the GOF virologists cabal discusses the Influenza H7N9 gain of function experiments on Dispatch Radio (2013)
https://t.co/0IXqpBa4qP
Transcript here:
https://t.co/hRhdO29Tkp
YT Link:
https://t.co/GOnYQtdkJe
Should We Allow Scientists To Create Dangerous Super-Viruses?
https://t.co/QUUQtgd9As
Bird Flu Paper Is Published After Debate
https://t.co/T9Rfcq8Cjd
Special Science Issue with several papers
https://t.co/0TD8lqtjkp
Can Limited Scientific Value of Potential Pandemic Pathogen Experiments Justify the Risks? (@mlipsitch of CWG)
https://t.co/dBB3Bjgp5l
Reply to the Epistemological Perspective on Value of Gain-of-Function Experiments
https://t.co/oSESIYHS0d
Reply to โCan Limited Scientific Value of PPP Experiments Justify the Risks?โ
https://t.co/gSDmc81rGN
Cambridge Working Group Statement on PPPs:
https://t.co/y4i0aYR73e
PDF: https://t.co/UqfhPSGVMI
Signatories include Inglesby, Farzan, Lipkin, Mackay, Rambaut
https://t.co/SGOAHH9Cpl
CWG comments:
Marc Lipsitch
https://t.co/3AKCF7JNTF
Stanley Plotkin
https://t.co/jNg2G05MM3
Lynn Klotz
https://t.co/67qBizegw9
Carlos Moreno
https://t.co/blJZYtegrq
Steven Salzberg
https://t.co/GZSypUNHsq
Full Report (1009 Pages)
https://t.co/Fkji8LSoMD
Update Summary Risk and Benefit Analysis (RBA) of Gain of Function Research Progress (36 Pages)
https://t.co/KGxkgcsvmB
Governments & funders must urgently address the risks posed by gain-of-function research
https://t.co/5ksiBHdAIz
Scientists are creating a dangerous flu strain, just to prove they can
https://t.co/ItxnAnJgQy
A submission to the
CDC/HHS re Opposition to Lab-engineering of Potentially Lethal Pathogens
https://t.co/3dWUQRePOF
An open letter to the NSABB re the political and
ethical implications of lethal virus development
https://t.co/y9YQMVE4mW
(Can Someone tell Kawaoka, Fouchier et al and WIV)
Ethical Alternatives to Experiments with Novel Potential Pandemic Pathogens
https://t.co/BOsCuQrj91
2006 Host Range Restriction & Pathogenicity in Influenza Pandemics
https://t.co/uEWa3GLmQx
and
2008 Receptor specificity of influenza viruses (Japanese)
https://t.co/TwEkuQazH4
2011 Pathogenesis 1918 pandemic influenza virus
Watanabe & Kawaoka
https://t.co/Ll190z96Lo
2013 Crosstalk between animal and human influenza viruses
https://t.co/H5w4ph3JKT
More to Come if anyone is interested in Kawaoka's work?
Temporary Unroll @threadreaderapp
More from Billy Bostickson ๐ด๐&๐ ๐
1/X Bellagio Rockefeller Initiative (Global Virome Project)
Another look at some key people in the GVP & their media statements since January 2020 about "natural origin" and impossibility of a "lab leak"
Full List of 18 scientists in photograph is here:
https://t.co/yHoAjwQjI8
2/X
We have already looked closely at Dennis Carroll, Peter Daszak, George Gao, W. Ian Lipkin & seen their public statements supporting "natural origin" & hysterical attacks on "lab leak" theories.
This thread focuses on:
Michael Kurilla
Jonna Mazet
Edward Rubin (Metabiota)
3/X
If we look at the leadership team of GVP, you will see some familiar faces:
https://t.co/WdT8sNnfmy
Most familiar is probably Peter Daszak, the wealthy Treasurer, also with the key role of Secretary.
Note: USAID PREDICT Project - EcoHealthAlliance
4/X
The "Chair" is Dr. Dennis Carroll
We will have a look at his media statements on the coronavirus pandemic by inputting his name in Twitter search box (very easy!)
Note: Previously was Director of USAID Emerging Pandemic Threats Program
5/X Dennis Carroll's video media statements (1):
CNN
(note Qinghai Thangka positioned in background which Daszak also shows off in his videos obtained during EcoHealth virus hunt with
Another look at some key people in the GVP & their media statements since January 2020 about "natural origin" and impossibility of a "lab leak"
Full List of 18 scientists in photograph is here:
https://t.co/yHoAjwQjI8
2/X
We have already looked closely at Dennis Carroll, Peter Daszak, George Gao, W. Ian Lipkin & seen their public statements supporting "natural origin" & hysterical attacks on "lab leak" theories.
This thread focuses on:
Michael Kurilla
Jonna Mazet
Edward Rubin (Metabiota)
3/X
If we look at the leadership team of GVP, you will see some familiar faces:
https://t.co/WdT8sNnfmy
Most familiar is probably Peter Daszak, the wealthy Treasurer, also with the key role of Secretary.
Note: USAID PREDICT Project - EcoHealthAlliance
4/X
The "Chair" is Dr. Dennis Carroll
We will have a look at his media statements on the coronavirus pandemic by inputting his name in Twitter search box (very easy!)
Note: Previously was Director of USAID Emerging Pandemic Threats Program
5/X Dennis Carroll's video media statements (1):
CNN
(note Qinghai Thangka positioned in background which Daszak also shows off in his videos obtained during EcoHealth virus hunt with
Warnings ignored, and the stunning fact that the wealthiest country in the world is short of masks and gowns and ventilators - and possibly, hospital beds. Dr Dennis Carroll says it's time to rip off the bandaid on harsh #coronavirus\xa0measures. #COVID19 pic.twitter.com/ZNZnhZnmPs
— Michael Holmes (@holmescnn) March 21, 2020
1/ Directed Evolution and Serial passage of RNA Viruses
A quick (I hope) thread on RNA viruses & some others, mainly for my own learning process, but also as evidence (as if it was needed) of what modern virology & microbiology is capable of doing to viruses in their laboratories
2/ In Vivo Continuous Directed Evolution
1 Recent advances in the field of in vivo continuous evolution
2 Advances in continuous culture of microbes enable continuous evolution
3 Viruses, prokaryotes, & eukaryotes mediate in vivo continuous evolution
https://t.co/BfR0B2Hwsf
3/ Continuous Directed Evolution of Biomolecules
By greatly accelerating laboratory evolution, PACE may provide solutions to otherwise intractable directed evolution problems and address novel questions about molecular evolution.
https://t.co/G3mIptI54H
4/ CDE for Strain & Protein Engineering
Inducible hypermutator systems accelerate strain evolution without compromising genome integrity.
Site-specific in vivo mutagenesis strategies have facilitated continuous protein engineering.
Automation
5/ Targeted mutagenesis:
A sniper-like diversity generator in microbial engineering
https://t.co/wdKyXghRYe
Advances in the directed evolution of proteins
https://t.co/1xXTtw1i3i
In vivo continuous directed evolution
https://t.co/xKRVSjVvo4
A quick (I hope) thread on RNA viruses & some others, mainly for my own learning process, but also as evidence (as if it was needed) of what modern virology & microbiology is capable of doing to viruses in their laboratories
2/ In Vivo Continuous Directed Evolution
1 Recent advances in the field of in vivo continuous evolution
2 Advances in continuous culture of microbes enable continuous evolution
3 Viruses, prokaryotes, & eukaryotes mediate in vivo continuous evolution
https://t.co/BfR0B2Hwsf
3/ Continuous Directed Evolution of Biomolecules
By greatly accelerating laboratory evolution, PACE may provide solutions to otherwise intractable directed evolution problems and address novel questions about molecular evolution.
https://t.co/G3mIptI54H
4/ CDE for Strain & Protein Engineering
Inducible hypermutator systems accelerate strain evolution without compromising genome integrity.
Site-specific in vivo mutagenesis strategies have facilitated continuous protein engineering.
Automation
5/ Targeted mutagenesis:
A sniper-like diversity generator in microbial engineering
https://t.co/wdKyXghRYe
Advances in the directed evolution of proteins
https://t.co/1xXTtw1i3i
In vivo continuous directed evolution
https://t.co/xKRVSjVvo4
Same covid-19 mutations are appearing in different places, which may or may not be strange....
41,000 mutations documented in 880 lineages.
Most in spike protein
What explains it?
https://t.co/MvHzUb4peo
https://t.co/PAwgC3lgsO
https://t.co/f9rnyFI0vq
https://t.co/wAlyNzuI0W
41,000 mutations documented in 880 lineages.
Most in spike protein
What explains it?
https://t.co/MvHzUb4peo
1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice https://t.co/TNE4tuLkqN
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 18, 2021
https://t.co/PAwgC3lgsO
2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2 https://t.co/B3eR764c1Z
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 18, 2021
https://t.co/f9rnyFI0vq
1. Reversion of molecularly engineered, partially attenuated, very virulent infectious bursal disease virus during infection of commercial chickenshttps://t.co/wOg1Ekl3Xp
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 24, 2021
2. Reversion to Virulence of Attenuated Canine Distemper Virus In Vivo and In Vitrohttps://t.co/xhjOEYEWTY
https://t.co/wAlyNzuI0W
3. pathogenic reversion of simian immunodeficiency virus SIVmac239Deltanef increases viral replicationhttps://t.co/jHmujgDVAC
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) February 24, 2021
November 3 - 9, 2019 -Wuhan Institute of Virology
International Training Course on Biosafety Laboratory Management and Technology
1. Daniel Feakes, head of UN Biological Weapons Convention implementation support agency
2. Renรฉ Courcol, quality control system expert, France's BSL
List of Lecturers with short bios at
November 3 - 9, WIV Training Course: https://t.co/Bsd9yO40JP
YUAN Zhiming Professor, Wuhan Institute of Virology, CAS (Deputy Director)
SONG Donglin, Professor, Wuhan Institute of Virology, CAS ( Deputy Director of Wuhan BSL-4 Laboratory.)
Dr. TONG Xiao Senior Engineer at WIV (Molecular Virology & (HIV) infection, mechanical & vaccine immunology) On-site Manager & Chief engineer for WIV BSL-4 Lab construction, maintenance & biosafety equipment R&D.
Zhengli Shi, Director of WIV Center for Emerging Infectious Diseases, now in charge of scientific activity in BSL3 & BSL4. Viral pathogen discovery through sequencing techniques, wildlife-borne viral pathogens, particularly bat-borne viruses since 2004.
DENG Fei, Principle Investigator in Research Group on Viruses Resources & Biotechnology in WIV, also Director of Microorganisms & Viruses Resource Center.
Graduate of ECUST, went to Great Lakes Forestry Center, Canada in 2001 & Wageningen University, NL to study baculovirus.
International Training Course on Biosafety Laboratory Management and Technology
1. Daniel Feakes, head of UN Biological Weapons Convention implementation support agency
2. Renรฉ Courcol, quality control system expert, France's BSL
List of Lecturers with short bios at
November 3 - 9, WIV Training Course: https://t.co/Bsd9yO40JP
YUAN Zhiming Professor, Wuhan Institute of Virology, CAS (Deputy Director)
SONG Donglin, Professor, Wuhan Institute of Virology, CAS ( Deputy Director of Wuhan BSL-4 Laboratory.)
Dr. TONG Xiao Senior Engineer at WIV (Molecular Virology & (HIV) infection, mechanical & vaccine immunology) On-site Manager & Chief engineer for WIV BSL-4 Lab construction, maintenance & biosafety equipment R&D.
Zhengli Shi, Director of WIV Center for Emerging Infectious Diseases, now in charge of scientific activity in BSL3 & BSL4. Viral pathogen discovery through sequencing techniques, wildlife-borne viral pathogens, particularly bat-borne viruses since 2004.
DENG Fei, Principle Investigator in Research Group on Viruses Resources & Biotechnology in WIV, also Director of Microorganisms & Viruses Resource Center.
Graduate of ECUST, went to Great Lakes Forestry Center, Canada in 2001 & Wageningen University, NL to study baculovirus.
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Week 1 highlights: getting shortlisted for YC W2019๐ค, acquiring a premium domain๐ฐ, meeting Substack's @hamishmckenzie and Stripe CEO @patrickc ๐คฉ
2/ So what is Brew?
brew / bru : / to make (beer, coffee etc.) / verb: begin to develop ๐ฑ
A place for you to enjoy premium content while supporting your favorite creators. Sort of like a โConsumer-facing Patreonโ cc @jackconte
(weโre still working on the pitch)
3/ So, why be so transparent? Two words: launch strategy.
jk ๐ a) I loooove doing something consistently for a long period of time b) limited downside and infinite upside (feedback, accountability, reach).
cc @altimor, @pmarca
4/ https://t.co/GOQJ7LjQ2t domain ๐ป
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5/ @ycombinator's invite for the in-person interview arrived that evening. Quite a day!
Thanks @patio11 for the thoughtful feedback on our YC application, and @gabhubert for your directions on positioning the product โ set the tone for our pitch!
Week 1 highlights: getting shortlisted for YC W2019๐ค, acquiring a premium domain๐ฐ, meeting Substack's @hamishmckenzie and Stripe CEO @patrickc ๐คฉ
2/ So what is Brew?
brew / bru : / to make (beer, coffee etc.) / verb: begin to develop ๐ฑ
A place for you to enjoy premium content while supporting your favorite creators. Sort of like a โConsumer-facing Patreonโ cc @jackconte
(weโre still working on the pitch)
3/ So, why be so transparent? Two words: launch strategy.
jk ๐ a) I loooove doing something consistently for a long period of time b) limited downside and infinite upside (feedback, accountability, reach).
cc @altimor, @pmarca
4/ https://t.co/GOQJ7LjQ2t domain ๐ป
It started with a cold email. Guess what? He was using BuyMeACoffee on his blog, and was excited to hear about what we're building next. Within 2w, we signed the deal at @Escrowcom's SF office. Youโre a pleasure to work with @MichaelCyger!
5/ @ycombinator's invite for the in-person interview arrived that evening. Quite a day!
Thanks @patio11 for the thoughtful feedback on our YC application, and @gabhubert for your directions on positioning the product โ set the tone for our pitch!
