November 3 - 9, 2019 -Wuhan Institute of Virology
International Training Course on Biosafety Laboratory Management and Technology
1. Daniel Feakes, head of UN Biological Weapons Convention implementation support agency
2. René Courcol, quality control system expert, France's BSL

List of Lecturers with short bios at
November 3 - 9, WIV Training Course: https://t.co/Bsd9yO40JP
YUAN Zhiming Professor, Wuhan Institute of Virology, CAS (Deputy Director)
SONG Donglin, Professor, Wuhan Institute of Virology, CAS ( Deputy Director of Wuhan BSL-4 Laboratory.)
Dr. TONG Xiao Senior Engineer at WIV (Molecular Virology & (HIV) infection, mechanical & vaccine immunology) On-site Manager & Chief engineer for WIV BSL-4 Lab construction, maintenance & biosafety equipment R&D.
Zhengli Shi, Director of WIV Center for Emerging Infectious Diseases, now in charge of scientific activity in BSL3 & BSL4. Viral pathogen discovery through sequencing techniques, wildlife-borne viral pathogens, particularly bat-borne viruses since 2004.
DENG Fei, Principle Investigator in Research Group on Viruses Resources & Biotechnology in WIV, also Director of Microorganisms & Viruses Resource Center.
Graduate of ECUST, went to Great Lakes Forestry Center, Canada in 2001 & Wageningen University, NL to study baculovirus.
DENG Fei (cont) focuses on identification & characterization of properties of tick-borne viruses including Crimean-Congo Hemorrhagic Fever virus (CCHFV) & new Bunyavirus, epidemiological investigation of viruses among vectors & humans, mechanisms of virus infection & pathogenesis
DENG Fei (cont) also commits to engineering of baculovirus-insect cell expression system, development of genetic engineering antigens, vaccines & novel bio-technology. She has published more than 50 papers, and obtained 2 patents.
NOTE: Arthropod (Database ZLS)
CHECK: Patents
ZHANG Bo
Ph.D. Molecular Biology & Virology at IMMB, University of Luebeck, Germany. Principle Investigator at WIV since 2009. Interested in replication mechanisms of positive single-stranded RNA viruses, viral pathogenesis, antiviral therapy & vaccine development.
ZHANG BO (cont) focuses on arthropod-borne flaviviruses (JEV, DENV) & alphavirus (CHIKV). Uses complete reverse genetic system to study functions of viral proteins during viral infection for ZIKV, JEV, DENV2, CHIKV, YFV, EV71 & CA16
NOTE: Arthropod(Database ZLS)
CHECK: 5 patents
WEI Hongping, Principle Investigator & Vice Director of center for Emerging Infectious Diseases of WIV, researches bacteriophages & lysins for treating infections due to multidrug resistant bacteria and rapid microbial detection for more than 10 years.
15 patents.
WEI Hongping (cont) developed novel chimeric lysins including ClyR, 1st lysin able to kill cariogenic Streptococcus mutans & found CBD from lysin PlyV12 attenuates virulence of S. aureus & enhances innate immunity to clear infection
Lectures bioethics
Member ethical committee CDC
WU Jia, Senior Engineer & biosafety officer at WIV.
In charge of biosafety in BSL-2 & BSL-3 laboratories.
Manages infectious animal experimentation in BSL-3 and BSL-4 labs.
So, he should fucking know if anything happened.
ZHENG Dasheng, Senior Engineer at the NBSL, WIV
Certified for completing Biocontainment Facilities & Operations Training courses in 2016 at Galveston National Laboratory, Texas
University of Johns Hopkins -Human Herpes-8 University of Sussex -improved GM biological mosquitocides
DU Tao, Engineer, 2004-2016: HIV1, enveloped virus infection mechanism & prevention strategies
Now WIV NBL-3 Biosafety officer
LIU Bobo, WIVTechnician
animal management & lab technician
Since 2013
lab system documents,
biosafety management of 3 wastes
gas/water/industrial waste
PENG Yun, P4-Assistant Lab Technician for experimental animals (5 yrs)
Good at blood sampling, intragastric administration, injection & anatomy of mice & very familiar with breeding of mice.
Nowadays she is breeding wild animals such as bats & ticks.
NOTE: Arthropods(Database)
From: https://t.co/Bsd9yO40JP
After leaked intel via Miranda Devine (Murdoch hack):
https://t.co/BZ3W1LV3Ru
that Zhnegli-Shi altered her database (records of bat ­viruses transmitted to other wild animals) by deleting keywords:
wildlife
arthropod vectors
Wild animal samples
Deleted:
viral pathogen data
emerging infectious diseases
cross-species infection
Last 3 replaced by:
bat
rodent
virus
wild animal (replaced 10 times with:
"bat & rodent" or "bat & rat"
"cross-species transmission of viruses in wild animals"
Database title changed from:
“Wildlife-borne viral pathogen database” to
“Bat & rodent-borne viral pathogen database”
"If WIV found missing link between RaTG13 & SARS-CoV-2 from animal vector, it would be in Shi’s database”
Scientists involved in arthropod research:
DENG Fei
ZHANG Bo
PENG Yun
Biowaste/ Biosafety Officers:
Wu Jia
Du Tao
Liu Bobo
Weak link: WEI Hongping (ethics) Miles Guo whistleblower?

More from Billy Bostickson 🏴👁&👁 🆓

"The coronavirus in Italy since September 2019"
Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy
First Published November 11, 2020
https://t.co/nhlccks5AS
Smashed Paywall thanks to @Sci_Hub
https://t.co/wWPFJMjjFJ

Maybe a coincidence but an agreement was recently signed by the authors' institute and guess who?
https://t.co/vh7qX3hyPD


The Lead Author specifically of the paper:
"Unexpected detection of SARS-CoV-2 antibodies in the prepandemic period in Italy"
is Giovanni Apolone of the "Fondazione IRCCS Istituto Nazionale Tumori" Milan, Italy


Some funding is involved....
Anyone good at Italian feel free to comment?


"You findee sars cov 2 in old sample back September time, we give you big fat red envelopeee, okey dokey?"

More has emerged regarding the Chinese connection
"Oncology research, Italy and China close to the collaboration protocol"
.https://t.co/Mt5hO9Dggc
1. Omicron Thread - A Compilation of Opinions

"finally, the time has slip and slid its slimy course through to us - and we're the vicious bastards of the new generation. we do not relent, and we should not be held to account for our ancestral faults"

https://t.co/mhJO6yOQRE


2. The Letter Chosen by the WHO

"It's amazing that the Xi variant seems to have somehow managed to evade detection..."

via @readomain

Why 'Omicron', Not 'Nu' or 'Xi'?

WHO Says Two Letters in Greek Alphabet Jumped to 'Avoid Stigma'

https://t.co/xnGR9XK2tF


3. The Omicron variant has been found in nearly every province of South Africa, as well as Botswana, Belgium, Israel, UK and Hong Kong.

This month, Israel held an exercise, The “Omega Exercise”, meant to prepare for a hypothetical, new COVID-19

4. Omicron Infographic

(appeared in Germany and Italy now)

https://t.co/oNFYBH1F1o


5. Overview of Omicron (B.1.1.529) from @nicd_sa

https://t.co/HN9csJqK0z
1. Mini Thread on Conflicts of Interest involving the authors of the Nature Toilet Paper:
https://t.co/VUYbsKGncx
Kristian G. Andersen
Andrew Rambaut
Ian Lipkin
Edward C. Holmes
Robert F. Garry

2. Thanks to @newboxer007 for forwarding the link to the research by an Australian in Taiwan (not on

3. K.Andersen didn't mention "competing interests"
Only Garry listed Zalgen Labs, which we will look at later.
In acknowledgements, Michael Farzan, Wellcome Trust, NIH, ERC & ARC are mentioned.
Author affiliations listed as usual.
Note the 328 Citations!
https://t.co/nmOeohM89Q


4. Kristian Andersen (1)
Andersen worked with USAMRIID & Fort Detrick scientists on research, with Robert Garry, Jens Kuhn & Sina Bavari among


5. Kristian Andersen (2)
Works at Scripps Research Institute, which WAS in serious financial trouble, haemorrhaging 20 million $ a year.
But just when the first virus cases were emerging, they received great news.
They issued a press release dated November 27, 2019:
1/10 What's all this then?
Biotech or biohazard?
A proposed federal lab in Butner would study the world's deadliest diseases
https://t.co/krnmueAd80
is it being built there or elsewhere, at Kansas University?


2/10 Shades of Plum Island?
New Proposal:
https://t.co/Lv3FgBgyas
GAO reports on security and safety lapses at Plum Island Animal Disease Research Center
Plum Island 1: https://t.co/pXSHgg1KKN
Plum Island 2:
https://t.co/O9oS0WXYOz


3/10 National Bio and Agro-Defense Facility
By memo dated December 4, 2008, the Department of Homeland Security named the Kansas site as the preferred location for the NBAF. On January 16, 2009, the record of decision was published in the Federal

4/10 Lucky ole Kansas!
The $1.25 billion facility is a biosafety level-4 laboratory and will replace the aging Plum Island Animal Disease Center.
NBAF is expected to be operational by 2022-2023.
Manhattan, Kansas, was selected as the location for NBAF.
https://t.co/kiokkFsT6v


5/10 The facility continues forward - Apr 19, 2020
https://t.co/JlstInKIRS
https://t.co/DtbLD9Tvxb
The 500,000 square foot building will have a $3.5 billion impact on the Kansas economy and many lab
1/4
Laulima Government Services (Fort Detrick BSL4) Contractor
(Alaka`ina Foundation) Hawaii DOD
Took over contract from Battelle

2/4
Tunnell Government Services
Jens Kuhn jumped ship from Battelle to steal

3/4 Jens Kuhn
https://t.co/rLxUmZoaQL
https://t.co/bOLwU9kTpW
https://t.co/WLi5NBTDEN
https://t.co/UF9gXup0El
https://t.co/5eVmln5sqN
wrote 6 tedious taxonomy papers with Fouchier
https://t.co/BAiXesvPxd
https://t.co/h4H4k7X4E3
Farzan & Kuhn ACE-2 &

4/4 Animal Origins of SARS Cov:
Insight from ACE2-S-Protein Interactions
https://t.co/sZp1fC4AdW
insights gained from study of SARS-CoV spike protein, which mediates viral entry & interaction with ACE2 receptor for SARS-CoV
Fang Li, Jens H. Kuhn, Michael Farzan


Kuhn's Appendix
https://t.co/QzTIyfdS0M
Global RNA Virome
https://t.co/zEdDcpoZKJ
S proteins of HCOVNL63 & SARS bind ACE 2 (with Farzan) https://t.co/K3RuTBo6R6!
Chapters 21, 22, 23 https://t.co/ckugrvRFwv
Chapter 57 in 1500 Page Book (Clinical Virology)
https://t.co/6ssn2LV0kS

More from All

How can we use language supervision to learn better visual representations for robotics?

Introducing Voltron: Language-Driven Representation Learning for Robotics!

Paper: https://t.co/gIsRPtSjKz
Models: https://t.co/NOB3cpATYG
Evaluation: https://t.co/aOzQu95J8z

🧵👇(1 / 12)


Videos of humans performing everyday tasks (Something-Something-v2, Ego4D) offer a rich and diverse resource for learning representations for robotic manipulation.

Yet, an underused part of these datasets are the rich, natural language annotations accompanying each video. (2/12)

The Voltron framework offers a simple way to use language supervision to shape representation learning, building off of prior work in representations for robotics like MVP (
https://t.co/Pb0mk9hb4i) and R3M (https://t.co/o2Fkc3fP0e).

The secret is *balance* (3/12)

Starting with a masked autoencoder over frames from these video clips, make a choice:

1) Condition on language and improve our ability to reconstruct the scene.

2) Generate language given the visual representation and improve our ability to describe what's happening. (4/12)

By trading off *conditioning* and *generation* we show that we can learn 1) better representations than prior methods, and 2) explicitly shape the balance of low and high-level features captured.

Why is the ability to shape this balance important? (5/12)
1. Mini Thread on Conflicts of Interest involving the authors of the Nature Toilet Paper:
https://t.co/VUYbsKGncx
Kristian G. Andersen
Andrew Rambaut
Ian Lipkin
Edward C. Holmes
Robert F. Garry

2. Thanks to @newboxer007 for forwarding the link to the research by an Australian in Taiwan (not on

3. K.Andersen didn't mention "competing interests"
Only Garry listed Zalgen Labs, which we will look at later.
In acknowledgements, Michael Farzan, Wellcome Trust, NIH, ERC & ARC are mentioned.
Author affiliations listed as usual.
Note the 328 Citations!
https://t.co/nmOeohM89Q


4. Kristian Andersen (1)
Andersen worked with USAMRIID & Fort Detrick scientists on research, with Robert Garry, Jens Kuhn & Sina Bavari among


5. Kristian Andersen (2)
Works at Scripps Research Institute, which WAS in serious financial trouble, haemorrhaging 20 million $ a year.
But just when the first virus cases were emerging, they received great news.
They issued a press release dated November 27, 2019:

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THE MEANING, SIGNIFICANCE AND HISTORY OF SWASTIK

The Swastik is a geometrical figure and an ancient religious icon. Swastik has been Sanatan Dharma’s symbol of auspiciousness – mangalya since time immemorial.


The name swastika comes from Sanskrit (Devanagari: स्वस्तिक, pronounced: swastik) &denotes “conducive to wellbeing or auspicious”.
The word Swastik has a definite etymological origin in Sanskrit. It is derived from the roots su – meaning “well or auspicious” & as meaning “being”.


"सु अस्ति येन तत स्वस्तिकं"
Swastik is de symbol through which everything auspicios occurs

Scholars believe word’s origin in Vedas,known as Swasti mantra;

"🕉स्वस्ति ना इन्द्रो वृधश्रवाहा
स्वस्ति ना पूषा विश्ववेदाहा
स्वस्तिनास्तरक्ष्यो अरिश्तनेमिही
स्वस्तिनो बृहस्पतिर्दधातु"


It translates to," O famed Indra, redeem us. O Pusha, the beholder of all knowledge, redeem us. Redeem us O Garudji, of limitless speed and O Bruhaspati, redeem us".

SWASTIK’s COSMIC ORIGIN

The Swastika represents the living creation in the whole Cosmos.


Hindu astronomers divide the ecliptic circle of cosmos in 27 divisions called
https://t.co/sLeuV1R2eQ this manner a cross forms in 4 directions in the celestial sky. At centre of this cross is Dhruva(Polestar). In a line from Dhruva, the stars known as Saptarishi can be observed.