I've seen many news articles cite that "the UK variant could be the dominant strain by March". This is emphasized by @CDCDirector.

While
this will likely to be the case, this should not be an automatic cause for concern. Cases could still remain contained.

Here's how: 🧵

One of @CDCgov's own models has tracked the true decline in cases quite accurately thus far.

Their projection shows that the B.1.1.7 variant will become the dominant variant in March. But interestingly... there's no fourth wave. Cases simply level out:

https://t.co/tDce0MwO61
Just because a variant becomes the dominant strain does not automatically mean we will see a repeat of Fall 2020.

Let's look at UK and South Africa, where cases have been falling for the past month, in unison with the US (albeit with tougher restrictions):
Furthermore, the claim that the "variant is doubling every 10 days" is false. It's the *proportion of the variant* that is doubling every 10 days.

If overall prevalence drops during the studied time period, the true doubling time of the variant is actually much longer 10 days.
Simple example:

Day 0: 10 variant / 100 cases -> 10% variant
Day 10: 15 variant / 75 cases -> 20% variant
Day 20: 20 variant / 50 cases -> 40% variant

1) Proportion of variant doubles every 10 days
2) Doubling time of variant is actually 20 days
3) Total cases still drop by 50%
Given these facts, I think headlines along the lines of "CDC warns UK variant could be dominant strain by March" can be misleading.

It has the consequence of instilling fear in the public, who are much more likely to misinterpret it as "there will be another bad wave".
The amount of pessimism still present and being proliferated does not match a reality where:

1) Cases and hospitalizations have fallen by more than half in the past month (and still falling)
2) We have administered the vaccine to 40M+ people, with 1M new vaccinations per day
Of course, there's a very possible scenario that we'll see a fourth wave beginning in mid/late March and peaking in April/May. I'm not trying to downplay that.

But I'm baffled to see such a high level of confidence from the public health community that a fourth wave will happen.
I was told last year that the purpose of restrictions/interventions is to "flatten the curve". That the main goal is to make sure we do not overwhelm our healthcare system.

That messaging seems to have been shifted to "eliminate the curve". Why?
It's possible that selection bias may be at play (i.e. experts that are more confident about a fourth surge will have their voices amplified).

In any case, the future trajectory of the variant is still unclear, at least from the data. It's good to tread with cautious optimism.

More from Society

Tomorrow, January 6th, MAGA chuds, Proud Boys, and white supremacists are planned to descend on Washington D.C. to contest the election. Among them will be NSC-131, a New England based neo-Nazi organization. Let's welcome them by saying hi to one of their members, Eddie Stuart!


Edward Stuart, from Chester, New Hampshire, has been a member of Nationalist Social Club (NSC) since the very beginning and is a staple participant in their actions. He is known in NSC chats as "Carl Jung" and is well connected in the New England Nazi scene.
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NSC-131 is a neo-Nazi group that was started in Massachusetts in early 2020 by Chris Hood. You can learn more about NSC and it's members in these threads:


Eddie describes his ideology as "Esoteric Hitlerism" which is an occult form of Nazism that literally worships Adolf Hitler as a god, or, specifically, as an incarnation of the Hindu God Vishnu. Here is Ed holding the RigVeda with some of his occult Nazi pals. Interesting Ed!
4/


Much of this ideological insight was gained from Eddie's Twitter, where he originally used his "Carl Jung" persona and reposts explicit neo-fascist content and racist memes. In one edited picture, Eddie can be seen at an NSC event in late June 2020 holding a Nazi Sonnenrad flag
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Viruses and other pathogens are often studied as stand-alone entities, despite that, in nature, they mostly live in multispecies associations called biofilms—both externally and within the host.

https://t.co/FBfXhUrH5d


Microorganisms in biofilms are enclosed by an extracellular matrix that confers protection and improves survival. Previous studies have shown that viruses can secondarily colonize preexisting biofilms, and viral biofilms have also been described.


...we raise the perspective that CoVs can persistently infect bats due to their association with biofilm structures. This phenomenon potentially provides an optimal environment for nonpathogenic & well-adapted viruses to interact with the host, as well as for viral recombination.


Biofilms can also enhance virion viability in extracellular environments, such as on fomites and in aquatic sediments, allowing viral persistence and dissemination.