11 of the wisest things ever said: 🧵

“The reading of all good books is like conversation with the finest men of past centuries.”

― René Descartes
"The man who asks a question is a fool for a minute, the man who does not ask is a fool for life"

― Confucius
"If you set out to be liked, you would be prepared to compromise on anything at any time, and you would achieve nothing."

― Margaret Thatcher
"Holding on to anger is like grasping a hot coal with the intent of throwing it at someone else; you are the one who gets burned."

― The Buddha
“Luck is what happens when preparation meets opportunity.”

― Seneca
“If a person gave away your body to some passerby, you’d be furious. Yet you hand over your mind to anyone who comes along, so they may abuse you, leaving it disturbed and troubled—have you no shame in that?”

― Epictetus
“The happiness of your life depends upon the quality of your thoughts.”

― Marcus Aurelius
“Character cannot be developed in ease and quiet. Only through experience of trial and suffering can the soul be strengthened, ambition inspired, and success achieved.”

― Helen Keller
“He who is cruel to animals becomes hard also in his dealings with men. We can judge the heart of a man by his treatment of animals.”

― Emmanuel Kant
"Being deeply loved by someone gives you strength, while loving someone deeply gives you courage.

― Lao Tzu
“How wonderful it is that nobody need wait a single moment before starting to improve the world.”

― Anne Frank
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@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2


@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj


@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o