What do peanuts have to do with lockdowns?

Unintended consequences.

A thread:

Peanut allergies were rare among American children up until the mid-1990s, when only four out of a thousand children under the age of eight had such an allergy. But by 2008, the rate had more than tripled, to fourteen out of a thousand.
No one knew why kids were becoming more allergic to peanuts. But the response was natural and seemingly rational: kids are vulnerable so keep them away from peanuts, peanut products, and anything that has been in contact with nuts of any kind.
But there was a severe and negative unintended consequence of this action, which was guided by the best intentions.
Researchers behind the authoritative LEAP study published in 2015 told half of participating parents to follow the standard advice for high-risk kids, which was to avoid all exposure to peanuts and peanut products.
The other half were given a supply of a snack made from peanut butter and puffed corn and were told to give some to their child at least three times a week.
Among the children who had been โ€œprotectedโ€ from peanuts, 17% had developed a peanut allergy.

In the group that had been deliberately exposed to peanut products, only 3% had developed an allergy.
One of the researchers: โ€œFor decades allergists have been recommending that young infants avoid consuming allergenic foods such as peanut to prevent food allergies. ... this advice was incorrect and may have contributed to the rise in the peanut and other food allergies.โ€
Awkward.

So what does this have to do with lockdowns?

Unintended consequences.
Dr. John Lee: "If lockdown is working, and stopping the spread of the virus, it might be reducing the circulation of milder versions among the population, while at the same time concentrating people with the most severe disease in hospital wards."

https://t.co/ltJwHpF6g6
"might the lockdown be causing more harm than good โ€” in this way as well as many others? Are our actions really helping overall? Or are they opposing a helpful evolutionary tendency of the virus, as well as economically hindering our ability to deal with it?"
The mental health implications of lockdown are obvious to but not fully appreciated. They should be.

https://t.co/bVfCfxxC3P
By enacting lockdowns we are sacrificing the young in a vain and misguided attempt to save the elderly. We could do both but are doing neither.

https://t.co/9AyppHA3eh
Suicides and overdose deaths seem to be positively correlated with lockdown.

https://t.co/EeEHDlaRvd
It's ok to change your mind. Lockdown may have seemed like the ethical option months ago, but the data doesn't back it up.

Consider Dr. Ari Joffe, who has written a paper that finds the harms of lockdowns are 10 times greater than their benefits.

https://t.co/om4m531xoh
Isolating ourselves from each other is much like isolating children from peanuts. It may feel like the right thing to do but that doesn't mean it is.

Sometimes the wisest thing to do is change your mind.
Dr. Sunetra Gupta: "...not only is it a good thing for young people to go out there and become immune, but that is almost their duty. Itโ€™s a way of living with this virus. Itโ€™s how we live with other viruses.

https://t.co/9Jsl22rMGK
Full credit to Greg Lukianoff and Jonathan Haidt for the peanut allergy story.

https://t.co/gI7FzS6TRF
And watch the interview here.

(End)

https://t.co/8PvUbOUskP

More from Health

1/15
Why can cefepime cause neurological toxicity?

And why is renal failure the main risk factor for this complication?

The answer requires us to learn about cefepime's structure and why it unexpectedly binds to a certain CNS receptor.

#MedTwitter #Tweetorial


2/
Let's establish a few facts about cefepime:

๐Ÿ”บ4th generation cephalosporin antibiotic
๐Ÿ”บExcretion = exclusively in the urine (mostly as unchanged drug)
๐Ÿ”บReadily crosses the blood-brain barrier (so it easily accesses the brain)

https://t.co/rjYG1BfGPR


3/
The first report of cefepime neurotoxicity was in 1999.

A patient w/ renal failure received high doses of cefepime and then developed encephalopathy, tremors, myoclonic jerks, and tonic-clonic seizures.

โœ…All symptoms resolved after hemodialysis.

https://t.co/u7JLVitQpp


4/
Cefepime neurotoxicity is surprisingly common, occurring in up to 15% of treated critically ill patients (w/ symptoms varying from encephalopathy to seizures).

๐Ÿ’กThe main risk factors = renal failure and lack of dose adjustment for renal function.

https://t.co/nxbnzSq8AR


5/
What about cefepime induces neurotoxicity?

One clue is that it's not the only antibiotic that causes neurotoxicity, particularly seizures.

This actually is a class effect w/ other beta-lactam antibiotics (including penicillins and carbapenems).

https://t.co/Lf4BhON9IY

You May Also Like

๐™Ž๐™๐™–๐™ง๐™ž๐™ฃ๐™œ ๐™ข๐™ฎ ๐™ฌ๐™ž๐™จ๐™™๐™ค๐™ข ๐‘พ๐’๐’'๐’• ๐’ƒ๐’† ๐’”๐’–๐’“๐’‘๐’“๐’Š๐’”๐’†๐’… ๐’Š๐’‡ ๐’•๐’๐’Ž๐’๐’“๐’“๐’๐’˜ ๐’– ๐’“๐’†๐’‚๐’… ๐’•๐’‰๐’† ๐’”๐’‚๐’Ž๐’† ๐’”๐’•๐’–๐’‡๐’‡ ๐’Š๐’ 50๐’Œ ๐’˜๐’๐’“๐’Œ๐’”๐’‰๐’๐’‘ ๐’๐’“ ๐’”๐’๐’Ž๐’†๐’๐’๐’† ๐’Ž๐’‚๐’๐’‚๐’ˆ๐’Š๐’๐’ˆ ๐’š๐’๐’–๐’“ ๐’Ž๐’๐’๐’†๐’š ๐’˜๐’Š๐’•๐’‰ ๐’”๐’‚๐’Ž๐’† ๐’๐’๐’ˆ๐’Š๐’„
Simple and effective way 2 make Money


Idea 1:- Use pivot level like 14800 in case of nifty and sell 14800straddle monthly expiry (365+335) exit if nifty closes on daily basis below S1 or above R1

After closing below S1 if it closes above S1 next day or any day enter the same position again vice versa for R1

Idea2:- Use R1 and S1 corresponding strikes multiple
Incase of R1 15337 take 15300ce
N in case of S1 14221 use 14200pe
Sell both and hold till expiry or exit if nifty closes below S1 or above R1 around closing
If the same bounces above S1 and falls below R1 re-enfer same strikes

Use same criteria for nifty, usdinr and banknifty

(This is must)Use this margin rule for 1lot banknifty pair keep 4Lax margin
For nifty one lot keep 3Lax
For usdinr 100lots keep 4Lax

I bet you if you do this on consistent basis your ROI will be more than 70% on yearly basis.

Couldn't explain easier than this

Criticisms are most welcomed.
@franciscodeasis https://t.co/OuQaBRFPu7
Unfortunately the "This work includes the identification of viral sequences in bat samples, and has resulted in the isolation of three bat SARS-related coronaviruses that are now used as reagents to test therapeutics and vaccines." were BEFORE the


chimeric infectious clone grants were there.https://t.co/DAArwFkz6v is in 2017, Rs4231.
https://t.co/UgXygDjYbW is in 2016, RsSHC014 and RsWIV16.
https://t.co/krO69CsJ94 is in 2013, RsWIV1. notice that this is before the beginning of the project

starting in 2016. Also remember that they told about only 3 isolates/live viruses. RsSHC014 is a live infectious clone that is just as alive as those other "Isolates".

P.D. somehow is able to use funds that he have yet recieved yet, and send results and sequences from late 2019 back in time into 2015,2013 and 2016!

https://t.co/4wC7k1Lh54 Ref 3: Why ALL your pangolin samples were PCR negative? to avoid deep sequencing and accidentally reveal Paguma Larvata and Oryctolagus Cuniculus?