BC HEALTH
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I think @SamAdlerBell in his quest to be the contrarian on Fauci gets several things wrong here. 1/

 First, the failure last year actually was driven by the White House, the #Trump inner circle. Watch what's happening now, the US' scientific and public health infrastructure is creaking back to life. 2/
I think Sam underestimates the decimation of many of our health agencies over the past four years and the establishment of ideological control over them during the pandemic. 3/
I also am puzzled why Tony gets the blame for not speaking up, etc. Robert Redfield, Brett Giroir, Deb Birx, Jerome Adams, Alex Azar all could have done the same. 4/
Several of these people Bob Redfield, Brett Giroir, Alex Azar were led by craven ambition, Jerome Adams by cowardice, but I do think Deb Birx and Tony tried as institutionalists, insiders to make a difference. 5/
I wrote to them privately and spoke publicly about the need to do more, but Sam misunderstands how long-time civil servants operate. The entire CDC staff could have resigned in protest, other agencies could have had everyone fall on their swords in protest as well. 6/
This isn't to excuse their behavior. It's just to say expecting people who have devoted their careers to places like CDC or NIH to resign in protest, speak out and get fired, is unrealistic. 7/
Lots can be said about the institutional failures--outside of Trump's influence--that happened last year. The testing debacle, the failure to real screen for new compounds against SARSCOV2 instead of just putting everything in the vaccine basket...8/
We were slow on masks. Yes. I agree. But there were also shortages of supplies even for healthcare settings in March. Remember the bandanas and panty-shields being worn by some on the wards, recycling N-95s? There was some worry about run on PPE by general public. 9/
Not an excuse, but context. The statement on herd immunity that Tony made. Dumb. Yeah. I get it. 10/
And Trump's obsession with loyalty twisted some of them to the breaking point. Redfield collapsed almost reflexively at the beginning. Birx thought she could control the situation. Tony though he could thread the needle, keep silent mostly, try to squeeze in some facts. 11/
No one came out of last year looking good and even if Fauci got accolades from some, those in public health saw what was happening. Shit was flying everywhere, everyone got soiled. 12/
But the biggest problem about @SamAdlerBell piece is not that it's slightly obsessive on Fauci (and I won't even start on the ACT UP sections, since I was there for many of these events), but gets the politics wrong in a big way. How so? 13/
At the end of the article Sam suggests that Tony should have resigned to lead the resistance. I mean, please. And then a bureaucrat arose to lead us. Really? The director of NIAID was going to be at the barricades? 14/
The big political question was NOT where was Dr. Fauci last year, but where were WE? Why didn't those not in government service rise up when the stakes were so much lower for resistance for us? Why didn't all the major non-governmental institutions mobilize on the pandemic? 15/
Many of us in public health were writing furiously about the failures of what was happening, as were others, but no one was doing the mobilization work to tip the scales from op-eds to direct action. 16/
Yes, those in government service do have to answer for their silence last year, but so do we. I am not holding up Fauci as a hero, but flipping him into the anti-hero of the story doesn't work either. 17/
I just posted a report from Brazil, about how Bolsanaro's policies drove the pandemic in Brazil. A fish rots from the head down. Trump and his circle hold the vast majority of blame for 2020 and our predicament today. It's just true. 18/
Bolsanaro's health ministers resigned and he just got other ones. This was also Trump's MO for 4 years, anyone who left, got replaced with people increasingly more loyal. The late arrival of Scott Atlas is a case in point here. 19/
So as a political history this piece fails. That's my main point. I've said terrible things about Fauci in the past in the press during the height of the AIDS epidemic, trashed Obama on global health/HIV in the 2000s. "Heroes" shouldn't be immune from criticism. 20/
Would it have been great if one by one federal scientists got to the mic and denounced Trump in 2020? Yeah, sure. And I want to be 35 again. Not gonna happen. 21/
The most startling thing to me and which no one has written about yet is why the rest of us were frozen like deer-in-the-headlights? 400,000 dead and "the resistance" to it all from outside the Administration was mostly in strongly worded op-eds. 22/
The press played the both sides game early on--kept saying "experts disagree" when Trump's policies were patently insane. This is the @NYTimes political desk's lingering shame, which they will never admit. 23/
Members of Congress sat on their hands. Mayors, governors just tried to keep their own cities and states from going under, but many aided and abetted the President. 24/
But political advocacy organizations, non-governmental actors could have mobilized. We did for the Women's March, after the Parkland shootings, for the March for Science. Yeah. big in-person events were a no-no, still are, but big not-in-person-events didn't happen either. 25/
In the aftermath of all of this, this is what's worry. Tony will retire soon. Take him off the playing field. Now what? We have to rebuild public health, not because of its failures last year, but because it was in shambles before 2020. 26/
We made our beds long before Trump. No national healthcare, a weak social safety net, a desperately under-funded and under-resourced public health infrastructure coast to coast under Republicans and Democrats. 27/
If Tony had spoken out all these structural issues would remain and frankly, it's the structures that outlast us, pave the way for crises out years into the future. 28/
And what are we going to do about that? end/

More from Gregg Gonsalves

Gregg Gonsalves
Gregg Gonsalves
@gregggonsalves
I've spent the past year as angry as I've been since the early days of the AIDS epidemic when I had to bury friends in their 20s, 30s because our government didn't care if gay men lived or died from a new virus among us. 1/


Some were put off by my anger, some thought scientists shouldn't be political or if they were tone it down a bit. 2/


I work in public health. I am not a basic scientist or a theoretician. I work in a field that is hemmed in by history and politics on every side. 3/


From the 19th century onwards, we've known that who lives and who dies isn't just a function of biology. The data support this thesis, we call them the social determinants of health. 4/


My friend and colleague Paul Farmer calls out these determinants in more direct terms as pathologies of power, structural violence. 5/
LIFE
Gregg Gonsalves
Gregg Gonsalves
@gregggonsalves
Eight years ago, Spencer Cox died of #AIDS. He had access to #antiretroviral therapy, but in his own struggles with #depression and substance use, he stopped taking them. 1/

Spencer left college, dropped out like me in the 80s, and we both found ourselves in @actupny where we joined the Treatment and Data Committee, doing battle with drug companies, the @US_FDA, the @NIH on a quest to save ourselves and our friends from near-certain death. 2/

Now everyone knows what those dark days before the advent of antiretroviral therapy were like. Waves upon waves of dying friends. A government who couldn't care less for the sick and dying. 3/

All this has happened before, and all this will happen again. AIDS. #COVID19. The next pandemic. The fire next time. 4/

And it changes you. Seeing so much death so young. Seeing those in power turn away from the catastrophe, even joke about it (find, listen to the tape of Larry Speakes in Oval Office w Reagan laughing about AIDS). 5/
HEALTH
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Gregg Gonsalves
Gregg Gonsalves
@gregggonsalves
Important tweet from @jaketapper. One amendment: mainstream media will try to change the subject too. It's not a new criticism, the deferential spirit among the political press corps has been noted since Didion wrote about it in the 1990s.


"Those who talk to Mr. Woodward, in other words, can be confident that he will be civil (“I too was growing tired, and it seemed time to stand up and thank him”), that he will not feel impelled to make connections between..." 1/

"what he is told and what is already known that he will treat even the most patently self-serving account as if untainted by hindsight..." 2/

"In this business of running the story, in fact in the business of news itself, certain conventions are seen as beyond debate. “Opinion” will be so labeled, and confined to the op-ed page or the Sunday-morning shows." 3/

"'News analysis' will be so labeled, and will appear in a subordinate position to the 'news' story it accompanies. In the rest of the paper as on the evening news, the story will be reported “'impartially,' the story will be 'even-handed,' the story will be 'fair.'” 4/
FOR LATER READ
Gregg Gonsalves
Gregg Gonsalves
@gregggonsalves
And this pathetic move by @JDVance1 isn't what is so odious about him. He's just a phony, all ambition, no real interest in public service. He made a big show out of moving back to #Ohio to start a group to work on the #opioid epidemic. 1/


I work on the opioids, on research on the epidemic, its relationship with HIV/HCV, overdose. I work with data from Ohio, so care deeply about what is going on there. I was excited. Until I started digging. There's no there there. 2/

More here. 3/

You can even read their IRS-990-N filing. Sure looks like @JDVance1 tried real hard on combatting the opioid epidemic in his state. Um. Not. 4/

Now he's moved on to venture capital. Money is more interesting than the suffering of the people of #Ohio I guess. 5/
ALL
Gregg Gonsalves
Gregg Gonsalves
@gregggonsalves
Here @playbookplus goes again: ‘HOW MUCH IS BIPARTISANSHIP WORTH?’ I don't know @politico, how many more months would you like the pandemic to drag on for? How many more dead? How many more people, businesses ruined economically? I'm sorry but this is garbage framing in a crisis.

Oh but this is what powerful people are talking about in DC! Might that point itself be examined with more seriousness than taking this BS at face value? Don't you understand, we just reflect back what people are saying? We are mirrors on the world, we offer no commentary.

If "very serious people" are talking about what "nice number" would be $1.3T, 1.2T and not what we need to get out of this mess, might it be worth saying, perhaps, this conversation w/o reference to epidemiologic or economic reality is just a failure of leadership, governance?
ECONOMY

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NotTheMacAnon
NotTheMacAnon
@NotTheMacAnon1
During a normal pregnancy, oxidative stress enhances antioxidant mechanisms that are capable of reacting by way of enzyme activity and non-enzyme free radical deactivators. However, pregnancy is also a state in which this adaptation and balance may be easily disrupted.

There is strong evidence that a chronicin flammatory reaction combined with the presence of a local oxidizing environment may play a vital role in the etiology and development of complications during pregnancy.

In late pregnancy, damage to DNA (especially when it is caused by oxidative stress) is associated with pre-eclampsia(PE), intrauterine growth restriction (IUGR), and the death of mothers in developing countries; it largely determines pregnancy – related susceptibility to diseases

The referential values of ROS and NOS and their minimal and safe concentrations or physiologically beneficial concentrations are yet to be determined.

The measurement of oxidative stress in vivo is perceived as controversial,

as the sen-sitivity and specificity of various oxidative stress markers is unknown.. .
HEALTH
Marina Amaral
Marina Amaral
@marinamaral2
[Thread]: Old school "medicine" ads obviously created by aliens.

Let's begin with cocaine toothache drops, for only 15 cents.


Dr. Batty’s asthma cigarettes were not recommended for "children under 6.”


Best prescription for malaria, chills and fever: Grove's tasteless Chill Tonic, obviously.

"It is simply iron and Quinine in a tasteless form".


The cheapest specific for the relief of cough: heroin.


There's also Dr Williams' Pink Pills for Pale People.
HEALTH
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Ryan Imgrund
Ryan Imgrund
@imgrund
DR CHRIS MACKIE (@Healthmac) is London’s Medical Officer of Health and a government advisor.

Yesterday, he said schools being open, “SLOWS the spread of COVID.”

For context, let’s look at 23 other times he misused data or gave a bad unsupported take.

🧵A THREAD🧵

...1/24


...2/24


...3/24


...4/24


...5/24
HEALTH
InspiredTeenTherapy
InspiredTeenTherapy
@SashaLPC
Thrd: Menstruation/Dysphoria

1/ Difficult periods are sometimes the first catalyst for young women becoming alienated from their bodies.

Some have given congratulatory speeches about the vague accomplishment of "becoming a woman."

2/ Others learned about periods through a mundane sex-ed lesson at school. Yet others knew very little about their periods except they are sometimes painful, can be embarrassing, and make activities they’d taken for granted,

3/ like swimming and outdoor play, all-of-a-sudden much more difficult.

When young women hate their periods, they might be told, in a matter-of-fact grumbling way, “well, nobody likes having a period, honey. It’s just a part of life.”

4/ On a personal note, till my early/mid 30s, I knew very little about the menstrual cycle. For me it had always been completely out of sight, out of mind. Once a month, I’d be reminded it exists and I’d have a kind of “oh crap!” moment.

5/ I’d complete the necessary hygiene and try to move on with my life. I was often plowing through various stages of this monthly cycle with little acknowledgement or understanding of how my entire mind, body, and mood was ebbing and flowing. Every month, for years on end.
HEALTH
Dr. Tory Eisenlohr-Moul, PhD \U0001f3f3\ufe0f\u200d\U0001f308
Dr. Tory Eisenlohr-Mou...
@eisenlohr_moul
Want to include the menstrual cycle in your scientific work, but aren't sure how to do it? My lab (@katjaschmalen) have just published an article on best practices for observational studies of the cycle! Thread below! 🧵

Despite decades of research on the menstrual cycle, empirical studies have not adopted consistent methods for operationalizing the menstrual cycle, resulting in confusion in the literature and limited possibilities to conduct systematic reviews and meta-analyses.

Below, I summarize this "how to" article, and relay some of the key points!

PARTICIPANTS: All participants should be naturally-cycling people with ovaries (remember that they are not necessarily "women"! 🏳️‍⚧️ ⚧).

We provide a Reproductive Status Questionnaire with rules for identifying naturally-cycling people (current function of the sexual organs and hormonal/other medications that stop the cycle).
HEALTH

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1. Let's talk about the effects of #climatechange on the world's forests, with a focus on the northwest of Canada. This is also about electoral #greenwash, and my duty as public servant and right as private Canadian citizen to speak freely about what I know.

2. Why am I compelled to speak? How am I free to speak? The answer is in the federal Values and Ethics Code of Coduct (VECC).


3. It can be career-limiting to criticize government policy when you work for government. Duty of Loyalty is very, very important. However, as VECC makes clear, it is not absolute. In fact SCoC has ruled twice in favour of citizen free speech as a higher ideal. In 1985 and 2001.

4. I am therefore perfectly comfortable showing you the scary things that are happening in the North under a warming climate. A failure to meet global GHG emissions targets is hurting Canada's forests in a way we used to think wouldn't happen for decades.

5. Warming temperatures and rising [CO2] could, in theory, help green the planet with more vigorous tree growth. But that's not what's happening. Don't believe the #greenwash. The positive effects are over and it is warm enough that we are now starting the into the negative.
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Magudeswarar Temple, Kodumudi
#Erode
#Tamilnadutemples 🚩

Situated on the banks of the river Kaveri, Magudeswarar Temple is one among Paadal Petra Shiva Sthalam. Kshetram is famous Parihara Sthala for Naga Dosham and for performing Tarpanam to the departed souls.


There are 3 sannidhi here for Paramashiva, Mahavishnu and Brahma Deva.

Sthala Puranam says that once Adisesha and Vayu Deva placed Meru parvat at the centre to decide who is stronger among them. Parvatam was held tightly by Adisesha and Vayu blew the wind to push Parvatham.


In this struggle, peak of meru  parvatham broke into 7 pieces and fell in different places as precious gems. Diamond fell at  Kodumudi as Magudeswarar. Panchamirtham abhishekam is very famous here. Vanni tree situated here is very old which contains medicinal values.


It is believed that Agasthiya Muni did Prathishta of Shiva Lingam here. As Adisesha is one of the reason for creation of the temple, this is famous Parihara Sthalam for Naga Dosham. It is believed that those who


who take a bath in the river Kaveri and worship paramashiva and mahavishnu, will be cured of diseases and will get relief from all illness.

Om Namah Shivaye
Om Namo Narayanaya
🙏🕉🙏
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First thread of the year because I have time during MCO. As requested, a thread on the gods and spirits of Malay folk religion. Some are indigenous, some are of Indian origin, some have Islamic


Before I begin, it might be worth explaining the Malay conception of the spirit world. At its deepest level, Malay religious belief is animist. All living beings and even certain objects are said to have a soul. Natural phenomena are either controlled by or personified as spirits

Although these beings had to be respected, not all of them were powerful enough to be considered gods. Offerings would be made to the spirits that had greater influence on human life. Spells and incantations would invoke their


Two known examples of such elemental spirits that had god-like status are Raja Angin (king of the wind) and Mambang Tali Arus (spirit of river currents). There were undoubtedly many more which have been lost to time

Contact with ancient India brought the influence of Hinduism and Buddhism to SEA. What we now call Hinduism similarly developed in India out of native animism and the more formal Vedic tradition. This can be seen in the multitude of sacred animals and location-specific Hindu gods
RELIGION
V\u0936\u0941\u0926\u094d\u0927\u093f
Vशुद्धि...
@V_Shuddhi
क्या आप जानते हैं कि क्या है, पितृ पक्ष में कौवे को खाना देने के पीछे का वैज्ञानिक कारण!

श्राद्ध पक्ष में कौओं का बड़ा ही महत्व है। कहते है कौआ यम का प्रतीक है, यदि आपके हाथों दिया गया भोजन ग्रहण कर ले, तो ऐसा माना जाता है कि पितरों की कृपा आपके ऊपर है और वे आपसे ख़ुश है।


कुछ लोग कहते हैं की व्यक्ति मरकर सबसे पहले कौवे के रूप में जन्म लेता है और उसे खाना खिलाने से वह भोजन पितरों को मिलता है

शायद हम सबने अपने घर के किसी बड़े बुज़ुर्ग, किसी पंडित या ज्योतिषाचार्य से ये सुना होगा। वे अनगिनत किस्से सुनाएंगे, कहेंगे बड़े बुज़ुर्ग कह गए इसीलिए ऐसा करना

शायद ही हमें कोई इसके पीछे का वैज्ञानिक कारण बता सके।

हमारे ऋषि मुनि और पौराणिक काल में रहने वाले लोग मुर्ख नहीं थे! कभी सोचियेगा कौवों को पितृ पक्ष में खिलाई खीर हमारे पूर्वजों तक कैसे पहुंचेगी?

हमारे ऋषि मुनि विद्वान थे, वे जो बात करते या कहते थे उसके पीछे कोई न कोई वैज्ञानिक कारण छुपा होता था।

एक बहुत रोचक तथ्य है पितृ पक्ष, भादो( भाद्रपद) प्रकृति और काक के बीच।

एक बात जो कह सकते कि हम सब ने स्वतः उग आये पीपल या बरगद का पेड़/ पौधा किसी न किसी दीवार, पुरानी

इमारत, पर्वत या अट्टालिकाओं पर ज़रूर देखा होगा। देखा है न?

ज़रा सोचिये पीपल या बरगद की बीज कैसे पहुंचे होंगे वहाँ तक? इनके बीज इतने हल्के भी नहीं होते के हवा उन्हें उड़ाके ले जा सके।
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Peter McCormack [Jan/3\u279e\u20bf \U0001f511\u220e]
Peter McCormack [Jan/3...
@PeterMcCormack
1/ So here is a thread on how I turned $32,000 into $1.2m and back to pretty much zero (once taxes are paid).

Just note, I am not bitter or salty in any way at all, the last 2 years have been an amazing ride - travelled the world, been wealthy, been poor.

2/ Dec '16, my advertising agency folded, I had a little bit of money left and I put $32k into Bitcoin and Ether. As it started to go up I diversified into everything, Monero, Dash, this that, any crap - even Ripplecoin. Everything just kept going up.

3/ By March I think I had around $300k and $500k by the summer. I used to take 25% out but towards the end of the summer I got greedy and put it all back in and by December it was $1.2m.

4/ Thinking I was an absolute genius I decided to start a bunch of businesses. As silly as it sounds I had this goal of making $5m as I wanted to buy Bedford Town Football Club and get them in the league, and as Crypto was going up forever I needed 6 months.

5/ So:
- Trading (income 1)
- Podcast (income 2)
- Mining (income 3)
- Mining pool (income 4)
- Consulting (income 5)

Yes - all of the above as a one-man army :)
LIFE