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I've been thinking about the debate of delayed vs. immediate 2nd dose for some time

Over past week, have become convinced that getting all doses out now is better

Its NOT a no-brainer

Reasonable people can (and do!!) disagree

So here's why my thinking evolved

Thread


Obviously, if you want to stick to the trials (reasonable position), then stay with standard interval

But soon, we'll be confronted with question -- do we give 2nd shot to some people or 1st shot to more people

Is there clinical trial evidence that 1 dose is helpful?

Yes

2/n

Yes

There is compelling data from Pfizer and Moderna trials that after about 10 d after 1 dose, you get 80-90% efficacy

https://t.co/38qlTYP77u

https://t.co/4V8SxM3tU5

So the BIG question is -- is that going to be durable beyond 21 to 28 days?

We don't know for sure

3/n

But while we may not be sure, it doesn't mean we have no idea

Here's one of our nation's most expert immunologists, @VirusesImmunity laying out her assessment of delayed vs immediate 2nd


What I take away from Dr. Iwasaki's thread and broader experience with vaccines is that it its unlikely that a short delay will harm protection

But we can't be sure

So why take this risk at all?

Why not just stay with the clinical trial?

Reasonable question

Here's why

5/9
You might want to ask yourself how an Air Force veteran ended up in a mob storming the Capitol, though.

What - and who - pushed her into thinking it was the right thing to do.

You might want to consider that many people like her are still out there.


Crazy thought, but what if we started focusing our efforts on fighting the sources of disinformation that pushed Ashli over the edge.

What if we taught people how to spot propaganda -- especially from their own political side?

If you're left leaning - like me - consider left wing propaganda.

(What? There's no such thing!)

Sure there is. The left scares its voters, same as the right.

(Yeah, but we scare them about REAL crises, not racist nonsense.)

Hmm.

The core idea isn't about left vs right. It's about power, and manipulating people to obtain that power.

And no, I'm not saying that #BothSides practice this to the same degree.

I'm saying we all have blind spots when we agree with what's being said and who's saying it.

When you're inclined to believe some thing A, it might be easy to get you to believe a related thing B. Then thing C, and D, and so on.

Until eventually you believe thing Q.

And as crazy as thing Q is, there are a disturbingly large number of letters that come after it.
Brief THREAD: OK, basics civics lesson to all these ignorant/dishonest R legislators/leaders/media folk who seem to have NO understanding of the law or the U.S. Constitution.

/1


1. If you enter my place of business & you start calling for an over-throw of the U.S. govt, or shout racist stuff or yell insults at me or my employees or my staff - I will ask you to leave & have the police remove you if U refuse. /2

2. In banning U from my place of business, I have NOT violated any of your rights. U have no right to disrupt my place of business and I have every right to not allow disgusting ppl like you to verbally abuse me, my customers or staff. /3

3. In fact, one of the great things abt American ideals (tho not always f/u in reality) that we should not allow discrimination based on a person's race, sex, religion, class, sexual orientation, disability, etc, BUT indvl citizens have a RIGHT to free association. /4

4. Similarly, businesses should not be allowed to discriminate based on race, sex, religion, class, sexual orientation, disability, etc, but can forbid/ban based on behavior/speech. /5