Every argument against raising the minimum wage involves pointing to some other part of our broken system as if it were a beloved cultural treasure to defend rather than just the next unacceptable thing that needs fixing.

They're talking about a military coup right now and if it doesn't happen we're going to be told the best way to heal is pretending it never happened.

This is how abuse works.

3,000 people are dying a day and after nearly a year of this Congress is releasing the barest fraction of the economic relief needed to keep people safe and only in exchange for the promise that we can't sue those who endangered the dead.

This is how abuse works.

We have a president who spent 4 yrs lying every time he opened his mouth, obvious lies everyone knew were lies, which his followers believed mostly because the sight of them believing lies caused the rest of us distress, and they loved our distress.

This is how abuse works.

We've endured the sight of police brutalizing our fellow citizens for years, a horror magnified by the knowledge that for Black people this brutality has been a constant way of life, but we're told change must wait, because we aren't asking right.

This is how abuse works.

We have been menaced and lied to and confronted with a daily litany of atrocity that has only made the Republican rank and file happier, and the only message we ever get is that we need to be better at relating to the feelings of people who find comfort in suffering.

It's abuse.

I'd like to speak the obvious necessary things about the Republican Party, the most central of which is that this is not an organization that is participating in democracy.

Rather, they are cynically utilizing our democracy's vulnerabilities.

The last two Republican Presidents to enter the White House did so without the popular vote.

The last Republican President to enter the White House with the popular vote did so in 1989.

Yet, when they win, they behave as though they have the mandate that comes with a landslide.

For example, they upend the healthcare program.

They give out trillions in corporate welfare.

They start torture programs.

They start surveillance programs.

They lie us into wars.

They gerrymander at every level they can. They deliberately disenfranchise. They make our elections so imbalanced they can get less votes than Democrats but win 60% of the seats.

They are not interested in democracy. They are not participating in a democracy.

When a Democrat actually does win the popular vote—by a lot—they behave as if they are a majority opposition.

They stall. They filibuster. They delay. They engage in deliberate sabotage to gain political advantage.

They are not participating in our democracy.

r u abbreving less rn?

Since the switch to 280 characters a year ago, we've seen an increase in people writing out full words and phrases.

All about the please and thank you.

With 280 characters, people are saying 'please' (+54%) and ‘thank you’ (+22%) more.

THANKS!!!!

💬💬💬

280 characters later, there are more ? and replies to Tweets. More room, more conversations!

Our pretensions to civilization have become very thin. Political violence was legitimized last year and is spreading wildly now. "Might makes right" is clearly the only "principle" behind freedom of speech. That's why Chinese Communists will never be censored by Big Tech.

When every "principle" becomes nothing but a ruthless exercise of power, it's not surprising that a growing number of people conclude they must demonstrate some sort of power in order to be taken seriously. Violence is the crudest exercise of power.

A well-run civilization makes it clear *universally* that violence is absolutely unacceptable. Giving free passes for irresponsible rhetoric and destruction to groups favored by the dominant political ideology of the State undermines that message.

We must also people peaceable means of expressing themselves and controlling their own lives, to relieve the pressures that can lead to violent outbursts and other forms of lawlessness. The less healthy discourse and freedom of action you have, the more pressure builds up.

It's dangerous when large numbers of people begin drawing the conclusion that might makes right, that laws and principles bend easily for those who have the political strength to bend them. Might makes right is the code of anarchy and barbarism, the antithesis of civilization.

@avacta's AVA6000 approved by MHRA. Superb news. First dosing 'around mid-year'; first data to come within 3-4 months after that.

A summary thread on the significance of AVA6000 - and #AVCT's pre CISION platform as a whole - to both the oncology industry and to AVCT itself. 1/10

In very basic terms, #AVCT's pre CISION chemotherapies are essentially reformulated versions of existing, approved chemotherapies that have been used on cancer patients for many years - decades, even.

The pre CISION tech is simply an attempt to improve the safety profile... 2/10

...of the chemo.

Most therapeutics going through clinical trials look for an improvement of at least 20% over the existing industry-standard drug. A 50% increase in efficacy would usually be considered an astonishing result.

In pre-clinical mouse models for #AVCT's AVA6000 3/10

...18 times more pro-doxorubicin was found in the tumour than in the heart. Compare that to the 1:1 ratio of the standard doxorubicin.

What this means is that the pre CISION tech could be used to enable the giving of doses to patients that are multiple times more potent... 4/10

...than standard chemotherapy drugs - either in the form of greater number of cycles of chemo, or in the potency of the individual dose.

For example, in #AVCT's pre-clinical trials, pro-dox (AVA6000) doses were 6x more potent than the standard dox doses.

The results? The...5/10