The new pooled testing initiation for MA schools is a game changer. Looking forward to seeing how this is going to roll out. Initial plans seem to call for pooled PCR testing for classes, followed by rapid antigen testing for pools that are positive. 1/
I don't think this is because college students stay at home all day and never have risky social interactions! 3/
https://t.co/e9Aktj8WU1
Community rates are surging so this is the time to bolster defenses against the virus. 6/ @AbraarKaran
9/ https://t.co/8lrg9PLU5c
https://t.co/VfnCM31aus
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global health policy in 2020 has centered around NPI's (non-pharmaceutical interventions) like distancing, masks, school closures
these have been sold as a way to stop infection as though this were science.
this was never true and that fact was known and knowable.
let's look.
above is the plot of social restriction and NPI vs total death per million. there is 0 R2. this means that the variables play no role in explaining one another.
we can see this same relationship between NPI and all cause deaths.
this is devastating to the case for NPI.
clearly, correlation is not proof of causality, but a total lack of correlation IS proof that there was no material causality.
barring massive and implausible coincidence, it's essentially impossible to cause something and not correlate to it, especially 51 times.
this would seem to pose some very serious questions for those claiming that lockdowns work, those basing policy upon them, and those claiming this is the side of science.
there is no science here nor any data. this is the febrile imaginings of discredited modelers.
this has been clear and obvious from all over the world since the beginning and had been proven so clearly by may that it's hard to imagine anyone who is actually conversant with the data still believing in these responses.
everyone got the same R
these have been sold as a way to stop infection as though this were science.
this was never true and that fact was known and knowable.
let's look.
above is the plot of social restriction and NPI vs total death per million. there is 0 R2. this means that the variables play no role in explaining one another.
we can see this same relationship between NPI and all cause deaths.
this is devastating to the case for NPI.
clearly, correlation is not proof of causality, but a total lack of correlation IS proof that there was no material causality.
barring massive and implausible coincidence, it's essentially impossible to cause something and not correlate to it, especially 51 times.
this would seem to pose some very serious questions for those claiming that lockdowns work, those basing policy upon them, and those claiming this is the side of science.
there is no science here nor any data. this is the febrile imaginings of discredited modelers.
this has been clear and obvious from all over the world since the beginning and had been proven so clearly by may that it's hard to imagine anyone who is actually conversant with the data still believing in these responses.
everyone got the same R
this methodology is a little complex, so let me explain what i did.
— el gato malo (@boriquagato) May 30, 2020
a few EU countries provide real day of death data. this lets us plot meaningful curves to show rate of disease change.
what struck me is how similar all the curves were.
everyone got the same shape. pic.twitter.com/bN0hILzoSl
This is a piece I've been thinking about for a long time. One of the most dominant policy ideas in Washington is that policy should, always and everywhere, move parents into paid labor. But what if that's wrong?
My reporting here convinced me that there's no large effect in either direction on labor force participation from child allowances. Canada has a bigger one than either Romney or Biden are considering, and more labor force participation among women.
But what if that wasn't true?
Forcing parents into low-wage, often exploitative, jobs by threatening them and their children with poverty may be counted as a success by some policymakers, but it’s a sign of a society that doesn’t value the most essential forms of labor.
The problem is in the very language we use. If I left my job as a New York Times columnist to care for my 2-year-old son, I’d be described as leaving the labor force. But as much as I adore him, there is no doubt I’d be working harder. I wouldn't have stopped working!
I tried to render conservative objections here fairly. I appreciate that @swinshi talked with me, and I'm sorry I couldn't include everything he said. I'll say I believe I used his strongest arguments, not more speculative ones, in the piece.
My reporting here convinced me that there's no large effect in either direction on labor force participation from child allowances. Canada has a bigger one than either Romney or Biden are considering, and more labor force participation among women.
But what if that wasn't true?
Forcing parents into low-wage, often exploitative, jobs by threatening them and their children with poverty may be counted as a success by some policymakers, but it’s a sign of a society that doesn’t value the most essential forms of labor.
The problem is in the very language we use. If I left my job as a New York Times columnist to care for my 2-year-old son, I’d be described as leaving the labor force. But as much as I adore him, there is no doubt I’d be working harder. I wouldn't have stopped working!
I tried to render conservative objections here fairly. I appreciate that @swinshi talked with me, and I'm sorry I couldn't include everything he said. I'll say I believe I used his strongest arguments, not more speculative ones, in the piece.
I appreciate his intellectual curiosity and effort. I have quibbles. But my big disappointment is there was no mention of unintended consequences, which we discussed and which are kind of THE core conservative concern on this issue.
— \U0001d682\U0001d68c\U0001d698\U0001d69d\U0001d69d \U0001d686\U0001d692\U0001d697\U0001d69c\U0001d691\U0001d692\U0001d699 (@swinshi) February 18, 2021
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Keep dwelling on this:
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs
