Both this thread and the outraged response threads are... something.
So, yesterday my daughter (9) was hungry and I was doing a jigsaw puzzle so I said over my shoulder \u201cmake some baked beans.\u201d She said, \u201cHow?\u201d like all kids do when they want YOU to do it, so I said, \u201cOpen a can and put it in pot.\u201d She brought me the can and said \u201cOpen it how?\u201d
— john roderick (@johnroderick) January 2, 2021
Unpleasant regulatory emotions will make me quit but she’ll just vent a bit and keep at it.
I went back to my jigsaw puzzle. She was next to me grunting and groaning trying to get the thing. I should say that spatial orientation, process visualization and order of operation are not things she... intuits. I knew this would be a challenge. But it was a rainy weekend.
— john roderick (@johnroderick) January 2, 2021
More from Venkatesh Rao
One other thing I should really clarify and that the @nytimes piece got *severely* wrong: while I believe there are very strong sociological and even causal links between rationalism and NRx (especially in the Silicon Valley homes bases) their ideological and methodological
— (((E. Glen Weyl))) (@glenweyl) February 14, 2021
IMO trying to correct whatever the NYT writer thought he knew/understood is futile. "Willing to be misunderstood by the NYT" should be the default stance unless you want to waste a lot of time correcting an obsolete 2013 map for people who don't care.
The thing is, the NYT still has enough normative cultural power, even as it has fallen from newspaper-of-record, that it takes a particular sort of heretical self-confidence to sort of ignore whatever they happen to be wrong about on any given week, whether or not it concerns you
A subtle shift has occurred in the workings of the Gell-Mann amnesia effect. It used to be an individual private amnesia re: media ("I'll believe myself when I am certain they got it wrong because I'm an expert, but still believe them when I am not"). Now it's a collective effect
A sort of common-knowledge threshold has been crossed lately. "Everybody knows that everybody knows the NYT is wrong on X across largish subcultures." It's no longer mutual beliefs being validated occasionally 1:1.
Poll: where is the temporal center of gravity of all your live projects based on average age of start-dates?
— Venkatesh Rao (@vgr) January 17, 2021
I suspect a healthy weighted average should be ~ (age-20)/2. So a 30 year old should be at 5, a 40 year old at 10, a 50 year old at 15 etc.
Standard deviation should be ~average/3 maybe, so distribution spreads as you age and accumulate projects and get better at them.
Other things being equal, people get good at starting in their 20s, at follow through in 30s, at finishing in 40s.
No point learning food follow through until you’ve found a few good starts to bet on. No point getting good at finishing until a few projects have aged gracefully.
I’m in the 7+ range myself. Probably 8-9. Slightly less than healthy for my age.
I suspect most self-judgments on being good starters/follow-through-ers/finishers are really flawed because of the non-ergodicity of project management skill learning. You can’t learn good practices for the 3 phases in an arbitrary order. On,y one order actually works.
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Further Examination of the Motif near PRRA Reveals Close Structural Similarity to the SEB Superantigen as well as Sequence Similarities to Neurotoxins and a Viral SAg.
The insertion PRRA together with 7 sequentially preceding residues & succeeding R685 (conserved in β-CoVs) form a motif, Y674QTQTNSPRRAR685, homologous to those of neurotoxins from Ophiophagus (cobra) and Bungarus genera, as well as neurotoxin-like regions from three RABV strains
(20) (Fig. 2D). We further noticed that the same segment bears close similarity to the HIV-1 glycoprotein gp120 SAg motif F164 to V174.
https://t.co/EwwJOSa8RK
In (B), the segment S680PPRAR685 including the PRRA insert and highly conserved cleavage site *R685* is shown in van der Waals representation (black labels) and nearby CDR residues of the TCRVβ domain are labeled in blue/white
https://t.co/BsY8BAIzDa
Sequence Identity %
https://t.co/BsY8BAIzDa
Y674 - QTQTNSPRRA - R685
Similar to neurotoxins from Ophiophagus (cobra) & Bungarus genera & neurotoxin-like regions from three RABV strains
T678 - NSPRRA- R685
Superantigenic core, consistently aligned against bacterial or viral SAgs