The pre CISION tech is simply an attempt to improve the safety profile... 2/10
AVA6000 approved by MHRA. Superb news. First dosing 'around mid-year'; first data to come within 3-4 months after that.
A summary thread on the significance of AVA6000 - and #AVCT's pre CISION platform as a whole - to both the oncology industry and to AVCT itself. 1/10
The pre CISION tech is simply an attempt to improve the safety profile... 2/10
Most therapeutics going through clinical trials look for an improvement of at least 20% over the existing industry-standard drug. A 50% increase in efficacy would usually be considered an astonishing result.
In pre-clinical mouse models for #AVCT's AVA6000 3/10
What this means is that the pre CISION tech could be used to enable the giving of doses to patients that are multiple times more potent... 4/10
For example, in #AVCT's pre-clinical trials, pro-dox (AVA6000) doses were 6x more potent than the standard dox doses.
The results? The...5/10
#AVCT isn't looking to improve chemotherapies by 25-30%, like most drugs in clinical trials.
Its pre CISION has the potential to improve the safety profile - and thus the... 6/10
https://t.co/XOEE45CBtZ
AVCT holds the global exclusive licence over...8/10
TMAC will produce Affimer Drug Conjugates - a potentially more powerful class of oncology treatment than Antibody Drug Conjugates. 9/10
First though, success for AVA6000 please!
Then hopefully @avacta's first TMAC drug to enter Phase I next year 10/10
More from Society
I’ll address every nonsense argument and lie used to defend the suicidal gender ideology Thats in vogue today:
3:45 - “So what if you don’t have gametes?”
It’s called a birth defect. You’re still male or female.
~5:00 *nonsense trying to say the sexes of seahorses could be swapped coz male carry the eggs*
male doesn’t produce eggs, he produces the sperm. He’s still the male. If I impregnated a chick then carried the amniotic sac in a backpack ‘til the baby was done I’ll still be male🤦♂️
5:10 - we could say there’s 4 sexes of fruit fly cause there’s 3 producers of different sized sperm
No. They’re still producing sperm. They’re males. This is idiotic. Is this whole video like this? (Probably. 99% likely. Abandon hope.)
~6:10 - hermaphroditism and sequential hermaphroditism exists therefore....
No. Some animals being hermaphrodites, which is meaningless w/o the existence of binary sex to contrast it to, still doesn’t make gender ideology or transgenderism valid.
Intersex ≠ transgenderism 🙄
6:20 - bilateral gynandromorphism is a disorder in some species (not in humans). Has nothing to do w/ “gender” or transgenderism.
Ova-testes in humans are also a disorder, usually found in those w/ the karyotype disorders that you ppl also try to appropriate (extra X’s/Y’s).
3:45 - “So what if you don’t have gametes?”
It’s called a birth defect. You’re still male or female.
*one horrible doctor does a horrible thing* "oh I guess gender is horrible" miss me with that transphobic nonsense
— Goob \u26a1 (@Goob999) February 17, 2021
Here's a video to even disprove your take on sex (not gender) and the binary:https://t.co/bpmqqJWoJX
~5:00 *nonsense trying to say the sexes of seahorses could be swapped coz male carry the eggs*
male doesn’t produce eggs, he produces the sperm. He’s still the male. If I impregnated a chick then carried the amniotic sac in a backpack ‘til the baby was done I’ll still be male🤦♂️
5:10 - we could say there’s 4 sexes of fruit fly cause there’s 3 producers of different sized sperm
No. They’re still producing sperm. They’re males. This is idiotic. Is this whole video like this? (Probably. 99% likely. Abandon hope.)
~6:10 - hermaphroditism and sequential hermaphroditism exists therefore....
No. Some animals being hermaphrodites, which is meaningless w/o the existence of binary sex to contrast it to, still doesn’t make gender ideology or transgenderism valid.
Intersex ≠ transgenderism 🙄
6:20 - bilateral gynandromorphism is a disorder in some species (not in humans). Has nothing to do w/ “gender” or transgenderism.
Ova-testes in humans are also a disorder, usually found in those w/ the karyotype disorders that you ppl also try to appropriate (extra X’s/Y’s).
It is simply not correct to point fingers at wind & solar energy as we try to understand the situation in TX. The system (almost) had a plan for weather (almost) like this. 1/x
It relied on very little wind energy - that was the plan. It relied on a lot of natural gas - that was the plan. It relied on all of its nuclear energy - that was the plan. 2/x
There was enough natural gas, coal and nuclear capacity installed to survive this event - it was NOT "forced out" by the wind energy expansion. It was there. 3/x
Wind, natural gas, coal and nuclear plants all failed to deliver on their expectations for long periods of time. The biggest gap was in natural gas! The generators were there, but they were not able to deliver. 4/x
It may be fair to ask why there is so much wind energy in ERCOT if we do NOT expect it to deliver during weather events like this, but that is an entirely different question - and one with a lot of great answers!! 5/x
Conservatives are using the Texas power chaos to argue against climate policy even as fossil-generated power outages dwarf the amount of renewables knocked offline during the historic deep freeze. President Biden and progressives have been slow to respond.https://t.co/UajKhptEAU
— E&E News (@EENewsUpdates) February 17, 2021
It relied on very little wind energy - that was the plan. It relied on a lot of natural gas - that was the plan. It relied on all of its nuclear energy - that was the plan. 2/x
There was enough natural gas, coal and nuclear capacity installed to survive this event - it was NOT "forced out" by the wind energy expansion. It was there. 3/x
Wind, natural gas, coal and nuclear plants all failed to deliver on their expectations for long periods of time. The biggest gap was in natural gas! The generators were there, but they were not able to deliver. 4/x
It may be fair to ask why there is so much wind energy in ERCOT if we do NOT expect it to deliver during weather events like this, but that is an entirely different question - and one with a lot of great answers!! 5/x