BK Dems can't continue with business as usual until we see real accountability for hate speech. We're calling on
@bkdems leadership to hold DL Lori Maslow accountable & for candidates to boycott the Jan 31 public forum until they do. 🧵 https://t.co/DNYAumTuSJ

Real talk.

The right as spent years trying to paint @NancyPelosi & @HillaryClinton as extreme leftists who will take your guns, sterilize your sons, outlaw Christianity, and tax you at 80%.

Meanwhile...

The far left has tried to insist that they were both Republican-lite.

1/

Some on the far left call them war mongering neoliberal corporate owned whores.

That's on a good day, for both.

None of these charges, by either side, are remotely true of course. Not that this matters to the people putting this shit out there.

2/

The facts are these.

@HillaryClinton and @NancyPelosi have been fighting people, usually white men, for tnings their entire lives.

With little respite.

At times they have had to make impossible choices and compromises just to beo let in the door. Most women have.

3/

It must be easy to be some 26 yo white dude who has never had anyone tell him no his whole life to sit in judgement of women like them.

"How dare she..."

...do what was necessary to get a place at the table.

...do exactly what men have been doing w/o your disapproval.

4/

Let's face it, most men suck when it comes to issues that don't pertain directly to their own self interests. White men are even worse. We just are.

Most men especially suck when it comes to women's issues and I mean really suck.

How many left leaning men fell to #MeToo?

5/

Demystifying Ghazwa-e-Hind. A #thread.

A recent video of Shoaid Akhter surfaced in social media creating a lot of controversy where the #Pakistani Cricketer can be seen suggesting invasion of India by using the term Ghazwa-e-Hind.
Radicalization of sportsmen seen off late
(1/10)

Some radical Islamic preachers believes that Ghazwa-e-Hind means a “Holy War against India”. As per this irrational & profane concept, there will be a fierce battle to secure victory over #India.
#Kashmir
(2/10)

#Pakistan-based terror groups, like JeM have been using Ghazwa-e-Hind as a Hadith to recruit, fund and justify its terror strikes as a religious holy war against #India.
#Kashmir
(3/10)

Some machiavellian people claim it is a prophecy that Muslim warriors will wage war against the #India.
Jaish & others falsely propagate that Jihad against India is considered holy in Islam & that those participating in it will be granted an easy entry into paradise.
(4/10)

However prolific scholars says that this is a made-up interpretation of some verse in The Holy Quran to mislead the gullible youth of #Pakistan into picking up arms and fighting its Army's personal battle against #India.
#Kashmir
(5/10)

My little Jacob Wohl story: August 2016, we're sitting around the trading turrets at my office on a bored to tears slow day. Our receptionist said someone was here for his 2pm appointment. None of us had an appointment on schedule. Who is it? we ask? Some guy named Jacob Wohl 1/

Jacob Wohl, for those out of loop, gained quite a bit of notoriety for becoming the youngest guy to ever get himself barred for life from the financial industry. Now he's waiting in our lobby to pitch something. We're a large merchant bank. 2/

Send him in, we said. In walks young Jacob asking to be seeded with $25mm to start a new hedge fund in exchange for an ownership stake in it. Oh, & he needs an office. And a Bloomberg station. And needs to borrow staff until he can hire some guys. And he needs a leased car... 3/

And he needs an answer today. Right now. Because there's a competing offer from Izzy Englander's firm Millenium (we know those guys well). We fight the urge to literally start laughing, but do ask him...hey, you the same guy who got banned by regulators? He didn't even flinch 4/

He went on about that being untrue & handed over a letter he said was from his lawyer who had confirmed he was not barred, had been vindicated but it 'just wasn't in the system yet at the SEC, CFTC'...whatever that means. 5/

Overall I think Labour will be a bit disappointed with how the ‘relaunch’ has started. Labour have given themselves a mountain to climb anyway through a year of inaction but the speech today lacked coherence, purpose and distinction from the government.

Starmer is (funnily enough) making a lot of the same mistakes Corbyn made in 2019. He is listing a ‘bold’ set of policy proposals that come across as disjointed and lacking connection to Britain’s priorities.

The policies themselves were basically good, I wouldn’t argue against them. But I would cringe whenever Labour came out with spending proposal after spending proposal in 2019 without any rationale or connection to a larger economic strategy. That’s what Starmer did today.

The questions that voters will have about Starmer’s speech are the same ones that voters will have had about Corbyn’s 2019 manifesto: why are these policies your priority, how can we afford them and why aren’t we doing these already?

The first one needs to be answered by diagnosing Britain’s problems and their causes. He doesn’t have to diagnose all of them. For the purpose of today he could have picked three that feed off each other: inequality, stagnant income growth and stagnant productivity.

@avacta's AVA6000 approved by MHRA. Superb news. First dosing 'around mid-year'; first data to come within 3-4 months after that.

A summary thread on the significance of AVA6000 - and #AVCT's pre CISION platform as a whole - to both the oncology industry and to AVCT itself. 1/10

In very basic terms, #AVCT's pre CISION chemotherapies are essentially reformulated versions of existing, approved chemotherapies that have been used on cancer patients for many years - decades, even.

The pre CISION tech is simply an attempt to improve the safety profile... 2/10

...of the chemo.

Most therapeutics going through clinical trials look for an improvement of at least 20% over the existing industry-standard drug. A 50% increase in efficacy would usually be considered an astonishing result.

In pre-clinical mouse models for #AVCT's AVA6000 3/10

...18 times more pro-doxorubicin was found in the tumour than in the heart. Compare that to the 1:1 ratio of the standard doxorubicin.

What this means is that the pre CISION tech could be used to enable the giving of doses to patients that are multiple times more potent... 4/10

...than standard chemotherapy drugs - either in the form of greater number of cycles of chemo, or in the potency of the individual dose.

For example, in #AVCT's pre-clinical trials, pro-dox (AVA6000) doses were 6x more potent than the standard dox doses.

The results? The...5/10