Transduction is the process by which foreign DNA is introduced into a cell by a virus or viral vector.

This nonspecific cation channel opens when illuminated with blue light, depolarizing the cell [4, 6] to trigger action potentials cells with high temporal precision [5]. Since the initial discovery of ChR2, many modifications have been made to refine the kinetic properties.

For example, ChETA, engineered to address limitations of spike fidelity with ChR2, has faster temporal kinetics and can maintain reliable spike precision up to 200 Hz [7].

Halorhodopsins (NpHR), light-gated chloride pumps activated by yellow light, allow for temporally specific hyperpolarization with single spike precision [8–10].

Archaerhodopsin-3 (Arch), a yellow light-activated outward proton pump, is an increasingly popular tool for light-induced hyperpolarization to inhibit cellular activity. Arch recovers spontaneously from inactivation with a much shorter recovery time than NpHRs [11].

Arch currents continue to increase with increasing light intensity, while NpHRs saturate [11]. The increased light sensitivity of the ArchT variant, along with better membrane targeting, allows for improved neural silencing both at cell bodies and terminals [12].

In continuum mechanics, stress is a physical quantity that expresses the internal forces that neighbouring particles of a continuous material exert on each other, while strain is the measure of the deformation of the material.

For example, when a solid vertical bar is supporting an overhead weight, each particle in the bar pushes on the particles immediately below it. When a liquid is in a closed container under pressure, each particle gets pushed against by all the surrounding particles.

The container walls and the pressure-inducing surface (such as a piston) push against them in (Newtonian) reaction.

These macroscopic forces are actually the net result of a very large number of intermolecular forces and collisions between the particles in those molecules. Stress is frequently represented by a lowercase Greek letter sigma (σ).

Residual stresses inside a plastic protractor are revealed by the polarized light.

🤫

Did the paedophiles create the virus?

I think so!

Is Joe Biden the paedophiles choice?

Jury’s out.

Scumbags

Lock them all up and f their vaccine.

Ashtangha Yoga or the eight limbs of Yoga-

Many people think Yoga is just an Indian physical exercise but that's wrong. Yoga is a way to connect with the Supreme in Hinduism and attain Moksha(liberation).
The proper yoga as described in Hindu scriptures consists of 8 limbs:

1) Yamas- They are the 5 ethical rules of Hinduism. The 5 Yamas are:
i) Ahimsa: Nonviolence (this also includes not eating meat)
ii) Satya: truthfulness
iii) Asteya: non-stealing
iv) Brahmacharya: chastity, sexual restraint
v) Aparigraha: non-avarice, non-possessiveness

2) Niyamas- They are the 5 "do's". The five Niyamas are:
i) Shaucha: purity of mind, speech and body
ii) Santosha: contentment
iii) Tapas: austerity, self-discipline
iv) Svadhyaya: study of Vedas(Holy books of Hindus)
v) Ishvarapranidhana: contemplation of the Ishvara (God)

3) Aasana or the physical yoga-
Asana is a posture that one can hold for a period of time, staying relaxed, steady, comfortable and motionless. The aasana postures are believed to have been given by Mahadeva (Hindu God) himself. Hatha Yoga Pradipika mentions 84 aasanas.

While #Tulane school of medicine is rightfully being exposed for its contemporary racism towards faculty, staff, students (and patients) due to the racist firing of Dr. Princess Dennar, it’s important to call out the deeply anti-Black history of this school, specifically... 1/

The way #Tulane became a private institution (originally was a public university) at the end of Reconstruction to avoid having to desegregate. The school charter says it was founded for “white men” only... but there’s more (much more) to this story... 2/

cw: medical racism

Tulane’s school of medicine rose to national prominence for its collection of human “specimens” in their anatomy museum “rivaled only by Harvard”. How did it acquire these “specimens” you might ask?

The collection was “curated” by a Dr. Edward Souchon... 3/

Dr. Souchon was mentored by the late James Marion Sims, the “father of modern gynecology”, who himself had started collecting body parts, organs, and skeletal remains from enslaved Black people during slavery. Souchon continued “curating” his own collection in horrific ways. 4/

The Souchon Collection grew over several decades, eventually touring the state as a traveling “public health” exhibit- nearly all of the body parts stolen, harvested and illicitly acquired from formerly enslaved and poor Black people via Charity Hospital. 5/

it seems to me that not many know that navalny is an avowed nationalist & racist and not just a blonde guy who likes to gently kiss his blonde wife before going to jail and watches “rick & morty”. so here’s a little thread and some of it is pretty personal.

here is navalny’s 2007 video. “a tooth without a root is called “dead”. a nationalist is someone who doesn’t want the russian root to be removed from the word “russia”. we have the right to be russian in russia, and we will defend it.”

i downloaded it to make sure it won’t disappear but it is still shared by navalny’s official youtube channel. btw, in this video, navalny is introduced in the caption as a “certified nationalist”.

here is another video navalny is not keen to share anymore, in which he compares muslims to cockroaches and flies and recommends shooting them with guns if swatters and shoes

here is a 2011 interview with navalny where he explains why he goes to the so-called “russian march”, a yearly nationalist gathering, and why he thinks it’s ok to collaborate with

#OTD 1901, Queen Victoria's funeral took place. Here's a little medical history THREAD (1/9) about one of Britain's longest reigning monarchs. 👇

"Queen Victorian on her death bed" by Emil Fuchs.

(2/9) On 7 April 1853, Queen Victoria became the first monarch to use chloroform to ease the pains of childbirth. Prince Leopold was born within 53 minutes of administration of the drug, which Victoria described as "delightful beyond measure.”

(3/9) The anaesthetic powers of chloroform was first discovered in 1847 by the Scottish physician James Young Simpson. He and his two friends experimented with it on the evening of November 4th. At first, they felt very cheerful and talkative. After a short time, they passed out.

(4/9) Impressed with the drug’s potency, Simpson began using chloroform as an anaesthetic. In December 1847, he delivered the first baby using it. Simpson nicknamed the girl “Saint Anaesthesia.” Her real name was Wilhelmina Carstairs, pictured here.

(5/9) During this time, Queen Victorian was pregnant with her sixth child. She heard of Simpson’s discovery and was keen to benefit from it, but royal doctors cautioned against it, claiming that painful contractions during labour were ordained by God.

The importance of T-cell immunity!
A recent study has found that after one dose of Pfizer’s vaccine, patients had a strong T-cell response, and a boosted antibody response after their second dose. This is good news for many reasons so let’s read up.

This study found that people’s antibodies were moderately effective against the original strain after their first dose of Pfizer’s vaccine, less effective against the B.1.1.7 variant, and were unable to neutralize the B.1.351 variant. Read what I said, that’s only after ONE dose.

However, they had strong T-cell responses against ALL known variants after the first dose. So why is this important? To recap, T-cells stimulate B-cells to make antibodies. Antibodies are just your first line of defense which is what is initiated when you get a vaccine.

It’s our T-cells that are responsible for long-term immunity. When antibodies diminish after your initial inoculation, your T-cells-will tell your B-cells it’s time to produce more antibodies. As long as your T-cells still recognize this virus and inform your B-cells they need

to produce antibodies, the vaccine is still doing its job. Your antibodies will get built up over and over again. Just FYI your TCRs and your BCRs target different parts of the Coronavirus’ spike protein. Antibodies can prevent infection, your T cell-responses ensure that those