It “took a village” to “raise”/create Andrew Wakefield - it is common for everyone to back away once accountability happens but Andrew Wakefield did not do this all by himself.

What about medical culture and who is not policed on professionalism that allowed him to get so far?

When I look at Wakefield, I see the same kind of lack of ethics evident in #Medbikini study

but Wakefield was far further down the spectrum

because he was doing invasive GI procedures on children for his study, funded by a lawyer

First: consent matters
Informed consent matters
What incentives exist in healthcare & academia that shaped his mindset & behaviors?

What was Wakefield rewarded for throughout his career?
Where did he NOT get questioned?

Look as this patent he had filed to compete vs MMR
Gibberish
+
His 🤑incentive

https://t.co/NRqXvBCGvB
Please note in his patent application Wakefield used those 12 samples that he cited in his @TheLancet study. He was not the only author. There were reviewers. There were editors. He was not alone in a cave. He was bullying his staff too

This was NOT “one man”
And lots of silence
“Joking” about kids crying & vomiting? Sounds like a massive jerk.

Erased/changed data

I have a hard time believing no one found him problematic before

Were people afraid to report?

When held accountable, he catastrophized, claiming he was being “persecuted”

Sound familiar?
Is Wakefield the only scientist or doctor funded by shady sources? Unfortunately no

Increasingly science serves the wealthy

The incredible irony is that he claims to be “exposing” the very thing that he himself is - HE was driven by money instead of sound science or ethics
My 🧵 on the pattern of anti-vaxxers targeting traumatized or marginalized groups - like refugees with valid distrust of authority/government - and/or those having a narrative of being “done wrong “by the system.

Wakefield claims his being held accountable = “persecution”
=hook https://t.co/l7XRK7jGoV
people who are manipulative & have no concern about harm/consequences they cause others

can be very good at storytelling

engage others’ emotions
tap into emotions of trauma

while themselves focus on wealth, fame, power

=manipulate emotions
use a “hook”
https://t.co/AFkQK0U5nz
Am unapologetic on protecting medical students’ & trainees’ ability to report
+
psychological safety

Check Wakefield types early
Who abuses power?
Students know

This hit piece written on me

Notice “hook” of unrelated shocking event to trigger emotions

https://t.co/jmiiBZ2OgI
Anyone who follows me knows I tweet incessantly on every topic

“vet” & “verify” = my mantra
my credibility as an expert witness depends on being factual

Regardless of individuals in question, professionalism must entail

-consistent standards
-verified facts
-verified identity
Personally, as a pediatrician, working in vulnerable & marginalized populations like refugees, the reviewers & editors that I face are EXTREMELY stringent on ethical standards

I don’t understand why we have repeated examples of others bypassing this level of scrutiny/standards
I happen to have a name that is likely unique in the world as well as throughout human history given the unusual spelling of multiple names.

I am not at risk of this kind of mistaken identity but many people I know who are Muslim are, even babies.

“Verify” for identity matters. https://t.co/gZTw0LXwHY
Can you honestly tell me that this Black male doctor

has ANY chance of ever committing the level of ethical violation & harm to our profession as Wakefield?

He was handcuffed for #publichealth best practices & volunteering

Our bias = wrong policing

https://t.co/HVr0xY2GsQ
There is SOOO much written on the problems with #Professionalism

= exactly WHY we end up with people like Wakefield
who get through gate after gate

while others, doing the RIGHT thing

are held back on petty issues or pushed out
FOR doing exactly what they were asked
The narrative that Wakefield

is an aberration
an individual who uniquely did unusual harm to our profession

is a false narrative

that fails to attribute accountability appropriately

Wakefield is a predictable result of our system

Who is rewarded for acting without #ethics?
@threadreaderapp please unroll

More from Health

1/16
Why do B12 and folate deficiencies lead to HUGE red blood cells?

And, if the issue is DNA synthesis, why are red blood cells (which don't have DNA) the key cell line affected?

For answers, we'll have to go back a few billion years.


2/
RNA came first. Then, ~3-4 billion years ago, DNA emerged.

Among their differences:
🔹RNA contains uracil
🔹DNA contains thymine

But why does DNA contains thymine (T) instead of uracil (U)?

https://t.co/XlxT6cLLXg


3/
🔑Cytosine (C) can undergo spontaneous deamination to uracil (U).

In the RNA world, this meant that U could appear intensionally or unintentionally. This is clearly problematic. How can you repair RNA when you can't tell if something is an error?

https://t.co/bIZGviHBUc


4/
DNA's use of T instead of U means that spontaneous C → U deamination can be corrected without worry that an intentional U is being removed.

DNA requires greater stability than RNA so the transition to a thymine-based structure was beneficial.

https://t.co/bIZGviHBUc


5/
Let's return to megaloblastic anemia secondary to B12 or folate deficiency.

When either is severely deficient deoxythymidine monophosphate (dTMP*) production is hindered. With less dTMP, DNA synthesis is abnormal.

[*Note: thymine is the base in dTMP]

https://t.co/AnDUtKkbZh

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I just finished Eric Adler's The Battle of the Classics, and wanted to say something about Joel Christiansen's review linked below. I am not sure what motivates the review (I speculate a bit below), but it gives a very misleading impression of the book. 1/x


The meat of the criticism is that the history Adler gives is insufficiently critical. Adler describes a few figures who had a great influence on how the modern US university was formed. It's certainly critical: it focuses on the social Darwinism of these figures. 2/x

Other insinuations and suggestions in the review seem wildly off the mark, distorted, or inappropriate-- for example, that the book is clickbaity (it is scholarly) or conservative (hardly) or connected to the events at the Capitol (give me a break). 3/x

The core question: in what sense is classics inherently racist? Classics is old. On Adler's account, it begins in ancient Rome and is revived in the Renaissance. Slavery (Christiansen's primary concern) is also very old. Let's say classics is an education for slaveowners. 4/x

It's worth remembering that literacy itself is elite throughout most of this history. Literacy is, then, also the education of slaveowners. We can honor oral and musical traditions without denying that literacy is, generally, good. 5/x