BC HEALTH
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ADHD, a thread (1)
If you have #ADHD & are struggling please know you’re not alone. This week on @Overview, we're talking about living w/ ADHD & Anxiety during the pandemic & many the stigmas & misconceptions that making things worse.

 I was diagnosed w/ ADHD when I was 7. And in so many ways it’s been a blessing. I love my energy, the hyper-focus, the calm I feel in chaos, the ability to & feel emotions so intensely. It’s allowed me to to see the world differently be in a constant state of wonder.(2)
But realizing all that has been a long, difficult journey so figured I’d share some of my own struggles as well as the resources from @HowtoADHD because Jessica's channel has been a game-changer for me.(3)
https://t.co/RO1ZGTlMq6
First off, #ADHD Attention Deficit Hyperactivity Disorder is a dumb description. It implies a deficit in attention & always hyper people. ADHD is a spectrum, & what we all have in common isn’t that we can’t pay attention. It’s that we have trouble controlling our attention.(4)
There are amazing analogies out there, like trying to watch 6 TV’s at once when someone else controls the remote. Or like driving a race car on city streets and spinning out whenever you try to turn.
My favorite is from my little brother who says, it’s like being in a forest full of distractions where you keep losing the trail… & when you finally find it, you’ll lock on so hard, you’ll follow it off a cliff. (5)
It gets confusing because it looks like a contradiction. Someone bouncing off the walls distracted & fidgeting. Then, they'll focus so hard for hours at a time, they forget about food, sleep or their loved ones? I THOUGHT THEY COULDN’T PAY ATTENTION? (6)
https://t.co/TXL9aOebDj
Turns out, both extreme states are the results of our problem with neurotransmitters like DOPAMINE & norepinephrine. If dopamine sounds familiar, it’s because it’s overhyped as the “pleasure chemical.” In reality, it also helps us learn through reward & motivation. (7)
Bottom line… because #ADHD brains have chronically low levels of dopamine… we have to overload ourselves just to feel it’s effects…(8) Here is a really good Valentines Day description from @HowtoADHD https://t.co/RDYueAi4BQ
Now, way back in our nomadic days, that kind of high-twitch brain wiring, might have been a benefit for an entire tribe, leading others in hunts or defending against invaders. But in the modern world, ADHD & it’s impulsivity create a constant struggle.(9)https://t.co/6mMV3fdjjg
Just a small list of negatives... We're more likely to lose things, make rash decisions, speed more, die in car crashes, get divorced, get fired, have trouble w/ finances, organization, & we're more susceptible to substance abuse, depression & suicide.(10) https://t.co/ZF8Iq8JoDU
A lot of those problems stem from our dopamine starved brains seeking stuff out that will allow us to feel, think & learn closer to the way others take for granted. Dopamine isn’t just some pleasure thing. It’s allows you to regulate emotional responses. (11)
Then there is the ADHD superpower HYPER-FOCUS.
Like, right now, I’m furiously locked into this thread, & breaking away is super disconcerting & almost painful. When honed & controlled it can supercharge your productivity. But when unchecked it can feel like this.(12)
There are a lot of really effective ways to thrive with ADHD. Cognitive therapy, exercise, post it notes everywhere! New experiences, crazy deadlines, the right profession, gamification, Jessica’s million tips on @HowtoADHD . Check out her TedTalk! (13) https://t.co/RqGMO8k484
But really, you can’t have a conversation about #ADHD without at least talking about medication.
Quick warning, my choices and perspective don’t reflect a “right” or “wrong” way to do things. I believe everyone should do what works for best for them. (14)
Some of my earliest #ADHD memories came from elementary school & these mortifying moments when class would be interrupted by a message over the intercom loudly broadcasting “Gadi please come to the nurses office… You forgot to take your medication.” (15)
I’m still not sure if it was an attempt to shame me into remembering to take them, or just the way they did things back then…But all of it would be made worse during recess when kids would laugh & call me weird & take turns asking me if I remembered to take my medicine.(16)
I wish, I could have understood that I wasn’t alone. That up to 16+ million Americans have #ADHD. That it's ok to have a different operating system & it didn’t mean I was dumb. I’m pretty sure my mom tried to explain it. But all I remember is being embarrassed & frustrated. (17)
And when the medication worked & allowed me to have control over what I choose what to focus on, I was even more angry that I needed it & wasn't like everyone else. (18)
Growing up, I also started to realize there were times I didn’t need it. I’d do fine if under intense deadlines, caught in a crisis or doing something I loved… which often made me question whether all of my struggles came from just not trying hard enough. (19)
We hear those words all our lives... JUST TRY HARDER! WHY CAN”T YOU DO THAT? IT SHOULDN’T BE THAT HARD. TRY HARDER. (20)
Imagine hearing those words again & again while trying as hard as you can, then going home & obsessing over how dumb u feel to the point that u forget everything else only to be jolted back into reality by someone asking you why you left the keys in the door. (21)
What people that don’t have #ADHD need to know is that THIS ISN’T ABOUT WILL POWER. There is a genetic difference in the way we create dopamine. (22)
https://t.co/PInu3lt8mi
Long story short, I’ve taken different medications on & off throughout my life. Each had it’s pros & cons & finding the right dosage & treatment takes time and a doctor who cares. And when I have, I’ve been able to control my mind & focus in a straight, linear way.(23)
However, over the last decade, I’ve also found myself in a profession that regularly activates my hyper-focus with intense deadline pressures, chaos & crisis & the ability to constantly explore new environments. For now, I've been able to navigate life without it. (24)
That’s not to say “don’t take medication…” or “eventually you won’t need it.” That’s not how it works. It’s a deeply personal & constantly evolving choice & people should do what works best for them. (25)
But in talking with Jessica for the Overview, I realized how a lot of my anger has closed me off to acknowledging some of the many tools that have allowed me to succeed. And a lot of that baggage plays into the stigma she’s working to undo. (26)
https://t.co/1jJe4K02F9
So here is a list of things that have helped me live with ADHD. Mindfulness, cognitive therapy, medication, exercise, constantly keeping lists and setting visual cues. Choosing a profession that plays to your strengths!(27)
Career choices are HUGE! For a long time I had the worst imposter syndrome in journalism that came with this ridiculous fear that my diagnosis would be found out & everything I did would be judged as, yeah but he has ADHD. (28)
Then I saw a couple of the most productive & talented journos I know talk openly #ADHD. I still remember seeing @yashar's thread & it brought me to tears. Still does. Please take a moment to read it. Thank you Yashar, it meant more than I can say. 🙏 (29)
https://t.co/7L6NJjSbA9
Turns out, Journalism can be amazing for #ADHD. The intense deadline pressures help trigger my hyper-focus & for those who struggle with repetitive routines, reporting can bring something different & unexpected everyday. (30) https://t.co/cIoGjpJBFz
In fact, there is a long list of jobs that can be perfect for #ADHD: Teaching, emergency care, writing, music, being a stylist, computer coder, graphic designer, a photographer, mechanic, entrepreneur… feel free to help! What other jobs have been a perfect fit? (31)
Finally, this is just one part of our look at mental health for @Overview. One of my best friends @WatchSavannah also takes a look at anxiety & the pandemic & I’m so incredibly grateful for the amazing insights & resources she's shared. Pls watch.
https://t.co/1jJe4K02F9

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#OurFavOnlineDoc \U0001fa7a\U0001f1f3\U0001f1ec\U0001f1ec\U0001f1e7\U0001f48e
#OurFavOnlineDoc 🩺🇳🇬🇬🇧...
@DrOlufunmilayo
HELLO: If you pee and every time you finish, your urine looks like this picture, you may have a serious medical illness.

Foamy urine especially if it is persistent and noticeable over time may mean you have a serious kidney problem.

Let’s talk about this today...
RT for others.


What are the features of a normal urine?

A normal urine should have a light yellow colour, painless, odourless (or faint smell), steady stream and should ideally not foam when you pee.

When there’s something wrong, then you see changes in all the above normal features of urine.

For instance if urine becomes very deep yellow, it may mean you are dehydrated;

If urine becomes painful or smells really really bad, it may mean you have an infection;

If urine has a poor stream, especially in a man, it may mean a prostate problem like cancer.

Do you get me?

So today let’s talk about Foamy Urine.

What are the things that can cause urine to suddenly be foamy. As I said in the first tweet, it MAY mean a serious medical illness like a serious kidney problem.

First things first- it does NOT always mean a problem but it may as well.

Now what are the causes of Foamy Urine:

1. SPEED-
If you pee really fast or with a lot of force, it may make your urine more foamy than usual. The speed and force makes the urine generate a lot of bubbles which tend to almost quickly disappear as it is formed in the toilet bowl.
HEALTH
James Salazar
James Salazar
@JamesSalazarMD
In medicine, reckoning with racism includes reappraising the very syntax we use every day. Proud to add my voice w/ @J_Ikeme and @RWGrantMD in this @JAMAInternMed pub addressing:

Does race/ethnicity belong in the first line of the patient

Some background: I’ve struggled with this question since early in medical school

Medical syntax is designed to communicate information in a predictable sequence with key elements prioritized to facilitate efficient communication and formation of an assessment and plan

2/

From preclinical lectures to Qbank questions to clerkship rotations, race/ethnicity was often prioritized in the same sentence as age + gender.

I grew accustomed to reading/hearing: a 70-year-old Black man w/ history of x, a 50-year-old Hispanic woman presented w/ y.

3/

However, when it came time for me to use race/ethnicity, there was always tension. Race/ethnicity are self/socially-ascribed identities that in clinical practice are almost always assumed by providers based on appearance. I was also concerned about the potential for bias

4/

I wondered how my own care would be impacted or not impacted by my ethnicity (Hispanic) – I have light skin so I’m not sure if my doctors would even identify me as such – but how would my care be different if I was presented as a 30-year-old Hispanic male?

5/
HEALTH
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Tamar Haspel
Tamar Haspel
@TamarHaspel
Let’s talk about ORGANIC.

Robert Paarlberg’s new book on the food system is out today, and here’s an excerpt.

He’s not a fan of organic, and he makes some good points but misses others.

Here we go.

Organic's biggest shortcoming is that you need more land to grow the same amount of food.

The yield penalty happens in almost every crop, in almost every study.

The gap could narrow with more research/varieties, but it won’t go away.

This has big, bad climate implications.

The second issue I have with organic, which Paarlberg shares, is that its basic criterion is naturalness.

Natural doesn’t mean safe, or even safer. A farming standard based on it forces farmers to sometimes use more dangerous, less effective tools.

On human health, there’s scant evidence that pesticide residues on conventional produce are harmful to consumers (though it’s possible farmworkers could be at risk).

What I don’t want is for folks who can’t afford organic to worry about feeding their kids conventional produce.

On the plus side, Paarlberg acknowledges that the organic standard has some real advantages for animal welfare.

This is why I buy organic animal products.

Many in the organic world would like more regs ensuring animals have decent lives.
HEALTH
Dylan Burnette
Dylan Burnette
@MAG2ART
Sarcomeres in cardiac myocytes (heart muscle cells) are mechanically coupled to focal adhesions through dorsal stress fiber-like structures. #cardiotwitter #CellBiology
1/13
A thread based on Figure 1

A mature adult cardiac myocyte is packed with sarcomeres, whose contractile forces are coupled to the extracellular environment. With sarcomeres so close to the plasma membrane, how can we study the nature of this coupling?
2/13


Short answer: find a model system where the sarcomeres are not so close to what the cardiac myocyte is attached to. Enter, iPS cell-derived cardiac myocytes. These are “immature” in culture as they resemble fetal or neonatal cardiac myocytes.
3/13


Our previous work on iPS cardiac myocytes reported that sarcomere containing myofibrils assembled on the top surface of the myocyte.
https://t.co/xIBCu3hG1W
4/13


The sarcomeres seemed to be connected to focal adhesions on the bottom of the cell by thin actin bundles that resembled the dorsal stress fibers (DSF) commonly found in non-muscle cells. This movie steps through a Z stack of a myocyte starting at the bottom of the cell.
5/13
HEALTH
Chris Hopson
Chris Hopson
@ChrisCEOHopson
1/23 We haven't had a lot to celebrate during this pandemic. But achieving the milestone of offering vaccine to the over 70s, health and care workers and the most clinically vulnerable just before target date is a huge cause for celebration, given the scale of the achievement.

2/23 When Margaret Keenan got her first jab in Coventry on December 8th last year, who’d have thought that, by Valentine’s Day, we’d have vaccinated over fourteen million people across the UK in just ten short weeks? Amazing, extraordinary and truly, really, world class!

3/23 I’ve been struck by how much joy and relief has been brought to those doing the vaccinations and those receiving them. A GP told me yesterday that nothing had given him greater pleasure in his long career. And that the patient's relief was sometimes overwhelming.

4/23 It's vital to recognise the extraordinary contribution of the staff and volunteers who have made this happen. One of my close family had their jab yesterday and was in awe of the volunteer standing outside in the freezing cold for a four hour shift meeting and greeting.

5/23 What I wanted to share in this thread was the slightly untold story of some of the extraordinary challenges the NHS has had to overcome to deliver this target. Requiring superhuman effort from NHS leaders and staff, way beyond the call of duty. Five challenges set out below.
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सा विद्या या विमुक्तये...
@raghav_aanya
कुंडली में 12 भाव होते हैं। कैसे ज्योतिष द्वारा रोग के आंकलन करते समय कुंडली के विभिन्न भावों से गणना करते हैं आज इस पर चर्चा करेंगे।
कुण्डली को कालपुरुष की संज्ञा देकर इसमें शरीर के अंगों को स्थापित कर उनसे रोग, रोगेश, रोग को बढ़ाने घटाने वाले ग्रह


रोग की स्थिति में उत्प्रेरक का कार्य करने वाले ग्रह, आयुर्वेदिक/ऐलोपैथी/होमियोपैथी में से कौन कारगर होगा इसका आँकलन, रक्त विकार, रक्त और आपरेशन की स्थिति, कौन सा आंतरिक या बाहरी अंग प्रभावित होगा इत्यादि गणना करने में कुंडली का प्रयोग किया जाता है।


मेडिकल ज्योतिष में आज के समय में Dr. K. S. Charak का नाम निर्विवाद रूप से प्रथम स्थान रखता है। उनकी लिखी कई पुस्तकें आज इस क्षेत्र में नए ज्योतिषों का मार्गदर्शन कर रही हैं।
प्रथम भाव -
इस भाव से हम व्यक्ति की रोगप्रतिरोधक क्षमता, सिर, मष्तिस्क का विचार करते हैं।


द्वितीय भाव-
दाहिना नेत्र, मुख, वाणी, नाक, गर्दन व गले के ऊपरी भाग का विचार होता है।
तृतीय भाव-
अस्थि, गला,कान, हाथ, कंधे व छाती के आंतरिक अंगों का शुरुआती भाग इत्यादि।

चतुर्थ भाव- छाती व इसके आंतरिक अंग, जातक की मानसिक स्थिति/प्रकृति, स्तन आदि की गणना की जाती है


पंचम भाव-
जातक की बुद्धि व उसकी तीव्रता,पीठ, पसलियां,पेट, हृदय की स्थिति आंकलन में प्रयोग होता है।

षष्ठ भाव-
रोग भाव कहा जाता है। कुंडली मे इसके तत्कालिक भाव स्वामी, कालपुरुष कुंडली के स्वामी, दृष्टि संबंध, रोगेश की स्थिति, रोगेश के नक्षत्र औऱ रोगेश व भाव की डिग्री इत्यादि।
ALL
Patrick McKenzie
Patrick McKenzie
@patio11
It’s underremarked upon that stablecoins accomplish basically all of the original design goals for Bitcoin qua a transactional mechanism (instant free value transfer anywhere), but that nobody cares about this because nobody ever cared about that part of the pitch.

“Why do people care about stablecoins then?”

A mix of “they encourage dollar-denominated liquidity in the cryptocurrency ecosystem and discourage withdrawal of the same” and “they’re good for money laundering.”

“But they make value transfer between exchanges much faster!”

This was a solved problem in traditional finance, too, mostly through the extension of credit. (It doesn’t matter how long settlement takes if there is sufficient trust to enable credit.)

The Bitcoin ecosystem is *positively allergic* to credit, so you have to call it a coin for them to accept it. And after you call it a coin they ignore everything the world has learned about credit, like risk management.

“Stablecoins aren’t credit!”

They’re pretty much exactly credit? A tether is a zero-coupon Bitfinex bond with a non-functioning call option. I
TECH
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Angad Singh
Angad Singh
@Singh7575
𝙎𝙝𝙖𝙧𝙞𝙣𝙜 𝙢𝙮 𝙬𝙞𝙨𝙙𝙤𝙢 𝑾𝒐𝒏'𝒕 𝒃𝒆 𝒔𝒖𝒓𝒑𝒓𝒊𝒔𝒆𝒅 𝒊𝒇 𝒕𝒐𝒎𝒐𝒓𝒓𝒐𝒘 𝒖 𝒓𝒆𝒂𝒅 𝒕𝒉𝒆 𝒔𝒂𝒎𝒆 𝒔𝒕𝒖𝒇𝒇 𝒊𝒏 50𝒌 𝒘𝒐𝒓𝒌𝒔𝒉𝒐𝒑 𝒐𝒓 𝒔𝒐𝒎𝒆𝒐𝒏𝒆 𝒎𝒂𝒏𝒂𝒈𝒊𝒏𝒈 𝒚𝒐𝒖𝒓 𝒎𝒐𝒏𝒆𝒚 𝒘𝒊𝒕𝒉 𝒔𝒂𝒎𝒆 𝒍𝒐𝒈𝒊𝒄
Simple and effective way 2 make Money


Idea 1:- Use pivot level like 14800 in case of nifty and sell 14800straddle monthly expiry (365+335) exit if nifty closes on daily basis below S1 or above R1

After closing below S1 if it closes above S1 next day or any day enter the same position again vice versa for R1

Idea2:- Use R1 and S1 corresponding strikes multiple
Incase of R1 15337 take 15300ce
N in case of S1 14221 use 14200pe
Sell both and hold till expiry or exit if nifty closes below S1 or above R1 around closing
If the same bounces above S1 and falls below R1 re-enfer same strikes

Use same criteria for nifty, usdinr and banknifty

(This is must)Use this margin rule for 1lot banknifty pair keep 4Lax margin
For nifty one lot keep 3Lax
For usdinr 100lots keep 4Lax

I bet you if you do this on consistent basis your ROI will be more than 70% on yearly basis.

Couldn't explain easier than this

Criticisms are most welcomed.
OPTIONSLEARNINGS , MONTHLY OPTIONS SELLING , OPTIONS LEARNING
Patrick McKenzie
Patrick McKenzie
@patio11
It’s underremarked upon that stablecoins accomplish basically all of the original design goals for Bitcoin qua a transactional mechanism (instant free value transfer anywhere), but that nobody cares about this because nobody ever cared about that part of the pitch.

“Why do people care about stablecoins then?”

A mix of “they encourage dollar-denominated liquidity in the cryptocurrency ecosystem and discourage withdrawal of the same” and “they’re good for money laundering.”

“But they make value transfer between exchanges much faster!”

This was a solved problem in traditional finance, too, mostly through the extension of credit. (It doesn’t matter how long settlement takes if there is sufficient trust to enable credit.)

The Bitcoin ecosystem is *positively allergic* to credit, so you have to call it a coin for them to accept it. And after you call it a coin they ignore everything the world has learned about credit, like risk management.

“Stablecoins aren’t credit!”

They’re pretty much exactly credit? A tether is a zero-coupon Bitfinex bond with a non-functioning call option. I
TECH
Delilah S. Dawson
Delilah S. Dawson
@DelilahSDawson
So here is a secret: Not everything I write goes anywhere. I have at least 4 books completely written and edited that never went on submission. I have books that stalled out at 20k. I have docs on my computer with opening paragraphs I don't remember writing. But! 1/

Every now and then an idea sticks with me like that corner of tortilla chip that just won't go down your throat. It happened with SPARROWHAWK, which began as 40k of a YA story, died, and was reborn as a comic, thanks to @christopher_j_r and @boomstudios. And now... 2/

It's happening with THE WILLOWS, a short story that you'll see in @UncannyMagazine next year. This Southern Gothic horror story began as an attempt to sell my next Romance to @AbZurdity after the Blud books in 2014 or so. And she didn't buy it. Guess why? 3/

Turns out, it wasn't a Romance! It was Southern Gothic Horror. Even the bones of it screamed strangeness, not sexiness. I loved the taste of the world, but I hadn't found the right story yet. Tried to write it 2 more times and failed. Until I finally understood what it was. 4/

So I took the 50 pages I'd written and cut half of them, twisting the story around from a gothy Romance inspired by the band the Civil Wars and turned it into a spooky descent into madness. And it looked back at me from the abyss as if to say, DUH. Sometimes... 5/
WRITING