Fintech firms will become digital layers around central banks, just like banks were physical layers

Central banks will create plug and play digital infrastructure (e.g. UPI, Aadhar) on which fintech products are built

Central banks will enable fintechs to replace banks

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On Wednesday, The New York Times published a blockbuster report on the failures of Facebook’s management team during the past three years. It's.... not flattering, to say the least. Here are six follow-up questions that merit more investigation. 1/

1) During the past year, most of the anger at Facebook has been directed at Mark Zuckerberg. The question now is whether Sheryl Sandberg, the executive charged with solving Facebook’s hardest problems, has caused a few too many of her own. 2/
https://t.co/DTsc3g0hQf


2) One of the juiciest sentences in @nytimes’ piece involves a research group called Definers Public Affairs, which Facebook hired to look into the funding of the company’s opposition. What other tech company was paying Definers to smear Apple? 3/ https://t.co/DTsc3g0hQf


3) The leadership of the Democratic Party has, generally, supported Facebook over the years. But as public opinion turns against the company, prominent Democrats have started to turn, too. What will that relationship look like now? 4/

4) According to the @nytimes, Facebook worked to paint its critics as anti-Semitic, while simultaneously working to spread the idea that George Soros was supporting its critics—a classic tactic of anti-Semitic conspiracy theorists. What exactly were they trying to do there? 5/

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@EricTopol @NBA @StephenKissler @yhgrad B.1.1.7 reveals clearly that SARS-CoV-2 is reverting to its original pre-outbreak condition, i.e. adapted to transgenic hACE2 mice (either Baric's BALB/c ones or others used at WIV labs during chimeric bat coronavirus experiments aimed at developing a pan betacoronavirus vaccine)

@NBA @StephenKissler @yhgrad 1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice


@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2


@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj


@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o
1/ Some initial thoughts on personal moats:

Like company moats, your personal moat should be a competitive advantage that is not only durable—it should also compound over time.

Characteristics of a personal moat below:


2/ Like a company moat, you want to build career capital while you sleep.

As Andrew Chen noted:


3/ You don’t want to build a competitive advantage that is fleeting or that will get commoditized

Things that might get commoditized over time (some longer than


4/ Before the arrival of recorded music, what used to be scarce was the actual music itself — required an in-person artist.

After recorded music, the music itself became abundant and what became scarce was curation, distribution, and self space.

5/ Similarly, in careers, what used to be (more) scarce were things like ideas, money, and exclusive relationships.

In the internet economy, what has become scarce are things like specific knowledge, rare & valuable skills, and great reputations.