Happy New Year 🪅🎉🥳

Goodbye 2020 and good riddance.

Thank you all for sharing the journey with me. Thank you for the questions, comments, gifs. We got through 2020. 2021 will be better.

2021 will be the year to Make Democracy Cool Again.

How about a few resolutions?

(Thread) Over the Cliff Notes: Impeachment #2

Let’s start with the Article of Impeachment itself: https://t.co/KRiPGstRwi

The charge: Incitement of Insurrection.

Spoiler: This is a slam-dunk in the impeach-and-convict department, and will create a moment of truth for the GOP.

1/ The basics:

🔹Impeachment requires a majority vote in the House. 

🔹Impeachment is followed by a Senate Trial.

🔹Conviction requires 2/3 of the Senate.

After conviction, preventing Trump from holding office again requires a simple majority vote.

2/ This is not a criminal trial.

The Constitution specifically says that a criminal trial may be appropriate AFTER impeachment and removal.

Defendants in a criminal trial have special protections because they stand to lose their liberty, property, or even their life.

3/ An impeached president stands to lose his job and the ability to hold the job again.

Therefore certain requirements for a criminal trial, such as the requirement that allegations be proven beyond a reasonable doubt, do not apply.

4/ In addition to charging Incitement of Insurrection, the Article invokes the 14th Amendment (sec 3) and Trump’s duty to faithfully execute the oath of office. 

Notice the 14th Amendment doesn’t give the procedure for determining when Section 3 applies.

The numbers on their face for the @FCC RDOF auction are exciting - lots of Gigabit winners. But it’s important to remember the job is just starting. These rural areas don’t magically get Gig today or tomorrow. 1/

The job is only done and the celebration can really only begin once we see that rural Americans are actually going to get the broadband they’ve been promised. 2/

And that’s the rub here - at least from preliminary indications, there are LOTS of question marks clearly hanging out there once you look past the gloss and proclamations. And since we won’t know for maybe 5 years if it worked, due diligence is essential now. 3/

A number of big winners have offered some service but never done Gig. This would be like giving hundreds of millions of $ to firms that have repaved residential streets to now design & build our interstate highway bridges. 4/

A number of big winners are using tech that has done Gig (maybe) only in tightly controlled applications that don’t look anything like rural America. This would be like giving interstate highway $ to firms who’ve built lots of scale models but never actually built a bridge. 5/

Count Giancarlo Cicogna was a member of the Ciga hotels clan. He was with Ghislaine Maxwell for 4 years. He was 'the man who moulded the Ghislaine we now see. He told her where to get her hair cut, and what to wear.'
https://t.co/XorCl9VKW6

There is a very Ghislaine like character named Madam Anais in the movie La Belle De Jour who runs a Brothel. The film was produced by Marina Cicogna.

Private View of 'Once Upon Time' an Exhibition of Photographs by Marina Cicogna Sponsored by Fiat at the Little Black Gallery,

My view Marina Cicogna looks like Dottie in the Disney Channel series WandaVision.

NY Times covered a story of Countess Marina Cicogna, a woman with a very intetesting life. I am sure she knows many secrets and that gives her power over people of influence.

Real talk.

The right as spent years trying to paint @NancyPelosi & @HillaryClinton as extreme leftists who will take your guns, sterilize your sons, outlaw Christianity, and tax you at 80%.

Meanwhile...

The far left has tried to insist that they were both Republican-lite.

1/

Some on the far left call them war mongering neoliberal corporate owned whores.

That's on a good day, for both.

None of these charges, by either side, are remotely true of course. Not that this matters to the people putting this shit out there.

2/

The facts are these.

@HillaryClinton and @NancyPelosi have been fighting people, usually white men, for tnings their entire lives.

With little respite.

At times they have had to make impossible choices and compromises just to beo let in the door. Most women have.

3/

It must be easy to be some 26 yo white dude who has never had anyone tell him no his whole life to sit in judgement of women like them.

"How dare she..."

...do what was necessary to get a place at the table.

...do exactly what men have been doing w/o your disapproval.

4/

Let's face it, most men suck when it comes to issues that don't pertain directly to their own self interests. White men are even worse. We just are.

Most men especially suck when it comes to women's issues and I mean really suck.

How many left leaning men fell to #MeToo?

5/

For those of us suffering & dying in Texas, the sociopathy of @GOP that leads to an astonishing lack of concern about our lives by evil folk like @GregAbbott_TX @GovernorPerry @TuckerCarlson @DanCrenshawTX et al who blatantly lie about what’s happening...1

...just to score political points - and protect the profits of energy companies - is almost incomprehensible. These are people who would claim Social Security caused 9/11 if it was convenient. What caused this catastrophe is vast vast majority from gas, then coal/nuclear...2

...then wind. The ONLY source of power that is delivering more than expected in budgeting is wind. But that’s not convenient to say for the oil/gas/coal industry, so the @GregAbbott_TX @GovernorPerry @DanCrenshawTX stand atop our dead bodies lying to protect the companies...2

...shockingly, the ONLY people in a position of state/national strength are the executives with the company that manages electricity in the state, @ERCOT_ISO. But they can’t tell the whole truth, because that would entail revealing how much stupidity was done here for profit...3

...of industry by Texas @GOP. If gas/nuke/nuclear/wind had been winterized - as they are everywhere else in the country - this would have largely been prevented. But it would have cost companies money, and that would cut into profits. If the gas lines has been buried deeper...3

@avacta's AVA6000 approved by MHRA. Superb news. First dosing 'around mid-year'; first data to come within 3-4 months after that.

A summary thread on the significance of AVA6000 - and #AVCT's pre CISION platform as a whole - to both the oncology industry and to AVCT itself. 1/10

In very basic terms, #AVCT's pre CISION chemotherapies are essentially reformulated versions of existing, approved chemotherapies that have been used on cancer patients for many years - decades, even.

The pre CISION tech is simply an attempt to improve the safety profile... 2/10

...of the chemo.

Most therapeutics going through clinical trials look for an improvement of at least 20% over the existing industry-standard drug. A 50% increase in efficacy would usually be considered an astonishing result.

In pre-clinical mouse models for #AVCT's AVA6000 3/10

...18 times more pro-doxorubicin was found in the tumour than in the heart. Compare that to the 1:1 ratio of the standard doxorubicin.

What this means is that the pre CISION tech could be used to enable the giving of doses to patients that are multiple times more potent... 4/10

...than standard chemotherapy drugs - either in the form of greater number of cycles of chemo, or in the potency of the individual dose.

For example, in #AVCT's pre-clinical trials, pro-dox (AVA6000) doses were 6x more potent than the standard dox doses.

The results? The...5/10