And since today is International Day of Women and Girls in Science, let's highlight a few of them - just a few women among thousands of others who helped shape the world we live in today.

Thread.

Dorothy Hodgkin discovered the structure of insulin after 36 years of work.

"I was captured for life by chemistry and by crystals."
Sophia Jex-Blake fought for women's rights to study medicine. She was involved in founding two medical schools for women.

"It seemed discreditable to Great Britain that all her daughters who desired a University education should be driven abroad to seek it."
Alice Augusta Ball developed the "Ball Method", the most effective treatment for leprosy during the early 20th century. She was 23.
Ada Lovelace is regarded as the first to recognize the full potential of computers and as one of the first computer programmers.

“That brain of mine is something more than merely mortal; as time will show.”
Valentina Tereshkova was (and remains) the first and youngest woman to have flown in space with a solo mission.

"I would enjoy flying to Mars. This was the dream of the first cosmonauts. I wish I could realize it! I am ready to fly without coming back."
Mary Anning is credited with the discovery of several dinosaur specimens that assisted in the early development of paleontology.

“It is large and heavy but… it is the first and only one discovered in Europe.”
Caroline Herschel was the first woman to discover a comet (she would spot seven more). She also detected three nebulae, in 1783.
Flossie Wong-Staal was the first scientist to clone HIV and determine the function of its genes, which was a major step in proving that HIV is the cause of AIDS.
Maria Gaetana Agnesi was the first woman to write a mathematics handbook and the first woman appointed as a mathematics professor at a university.
Nettie Stevens discovered the XY sex-determination system.
Rosalind Franklin made a crucial contribution to the discovery of the double-helix structure of DNA.

"Science and everyday life cannot and should not be separated."
Katherine Johnson performed the calculations that enabled humans to successfully achieve space flight.

“Let me do it. You tell me when you want it and where you want it to land, and I’ll do it backwards and tell you when to take off.”

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So, as the #MegaMillions jackpot reaches a record $1.6B and #Powerball reaches $620M, here's my advice about how to spend the money in a way that will truly set you, your children and their kids up for life.

Ready?

Create a private foundation and give it all away. 1/

Let's stipulate first that lottery winners often have a hard time. Being publicly identified makes you a target for "friends" and "family" who want your money, as well as for non-family grifters and con men. 2/

The stress can be damaging, even deadly, and Uncle Sam takes his huge cut. Plus, having a big pool of disposable income can be irresistible to people not accustomed to managing wealth.
https://t.co/fiHsuJyZwz 3/

Meanwhile, the private foundation is as close as we come to Downton Abbey and the landed aristocracy in this country. It's a largely untaxed pot of money that grows significantly over time, and those who control them tend to entrench their own privileges and those of their kin. 4

Here's how it works for a big lotto winner:

1. Win the prize.
2. Announce that you are donating it to the YOUR NAME HERE Family Foundation.
3. Receive massive plaudits in the press. You will be a folk hero for this decision.
4. Appoint only trusted friends/family to board. 5/

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A brief analysis and comparison of the CSS for Twitter's PWA vs Twitter's legacy desktop website. The difference is dramatic and I'll touch on some reasons why.

Legacy site *downloads* ~630 KB CSS per theme and writing direction.

6,769 rules
9,252 selectors
16.7k declarations
3,370 unique declarations
44 media queries
36 unique colors
50 unique background colors
46 unique font sizes
39 unique z-indices

https://t.co/qyl4Bt1i5x


PWA *incrementally generates* ~30 KB CSS that handles all themes and writing directions.

735 rules
740 selectors
757 declarations
730 unique declarations
0 media queries
11 unique colors
32 unique background colors
15 unique font sizes
7 unique z-indices

https://t.co/w7oNG5KUkJ


The legacy site's CSS is what happens when hundreds of people directly write CSS over many years. Specificity wars, redundancy, a house of cards that can't be fixed. The result is extremely inefficient and error-prone styling that punishes users and developers.

The PWA's CSS is generated on-demand by a JS framework that manages styles and outputs "atomic CSS". The framework can enforce strict constraints and perform optimisations, which is why the CSS is so much smaller and safer. Style conflicts and unbounded CSS growth are avoided.