BC HEALTH
Saved by @SteveeRogerr

It's been 13 months since my craniocervical fusion surgery and 7 months since my tethered cord surgery. My diagnoses were craniocervical instability, tethered cord, ME/CFS, MCAS, POTS, and mold illness (which may or may be fully explained by MCAS). 1/n

 Before my first surgery, I couldn't sleep inside a house b/c of mold illness/MCAS. I got paralyzed, unable to speak, and barely able to breathe, sometimes 8 or more times a day. This could result from tilting my head back, speaking too much, a loud sound, a tap on the head. 2/n
Traction (pulling my head away from my body) brought me back from these episodes. I couldn't ever be left alone. I wasn't bedbound, but I could do essentially nothing for myself. 3/n
By that point, my symptoms were extreme even for CCI, and they were quite unusual for ME/CFS. But I started out with classic ME/CFS -- PEM, POTS, unrefreshing sleep, cognitive impairment, low NK-cell function, wacky cytokines, sky-high IGGs for a bunch of viruses. 4/n
The last year has been HARD. These surgeries are brutal and hard to recover from. Needing a second surgery when I hadn't yet fully recovered from the first was emotionally and physically rough. 5/n
But... Yesterday, I went for a three-mile hike with a friend. I was tired afterward, but no PEM. I can do strengthening exercises and push myself, hard. I'm starting to be able to write again. I can talk to people for as long as I like. I can care for myself and my new puppy. 6/n
My POTS is now under control with a fairly low dose of Mestinon. It's surprising that the POTS is still there, and it may be that I was getting tiny CSF leaks that self-healed. I'm hoping that I won't need the Mestinon after a while. 7/n
My mold reactivity is SO MUCH BETTER. I still have MCAS and I'm taking MCAS tx. But I can now live in my own house, which hasn't been possible for the last four years. I spent many months essentially homeless. I'm inexpressibly thrilled to be in the house I so love. 8/n
For me. I think the mold/MCAS was the primary driver of my illness. I believe that mold exposures led to inflammation, particularly around my brainstem. This inflammation involved the release of cytokines that are known to damage collagen. This damaged my neck ligaments. 9/n
That led to craniocervical instability. My neck ligaments *may* have gotten damaged initially from a couple of bad concussions I had as a kid -- not enough to cause sx, but enough to decrease the space for my brainstem and make me less tolerant of inflammation in that area. 10/n
I no longer meet the criteria for ME. 11/n
I don't believe that surgery is the solution to ME. Only a subset of ME patients have the same problems I have, and unless you do, and unless your sx are quite bad, you wouldn't be a candidate for surgery anyway. No neurosurgeon would operate on you. 12/n
I do think my experience, and that of other pts like me, suggests that we should be looking hard at the role of MCAS in ME, and also at what's going on with ME pts' connective tissue. Many ME patients have EDS, but I don't, and connective tissue was still my problem. 13/n
I also think we really need to look at the role of mold in ME. My MCAS sx were nearly exclusively in response to mold exposure, and before I developed CCI, I recovered almost completely through extreme mold avoidance. Mold plays a key role for many many ME pts. 14/n
I think one of the key lessons we're learning from ME is that these contested illnesses are closely related to one another. ME, EDS, IBS, Lyme, autoimmune disease, CCI, MCAS -- they're all pieces of a bigger story. 15/n
And long Covid is part of that story too. 16/n
So I think we need to break down the silos between these communities, ones that divide patients from one another and researchers from one another. 17/n
I don't have EDS, but EDS research is relevant to me. EDS patients are my brothers and sisters. 18/n
Doctors and researchers who want to help pts with one of these diagnoses need to learn about the rest too. 19/n
This is a project of co-liberation. Solidarity, friends. Let's work together. /fin

More from Health

katya
katya
@kazbek
it seems to me that not many know that navalny is an avowed nationalist & racist and not just a blonde guy who likes to gently kiss his blonde wife before going to jail and watches “rick & morty”. so here’s a little thread and some of it is pretty personal.

here is navalny’s 2007 video. “a tooth without a root is called “dead”. a nationalist is someone who doesn’t want the russian root to be removed from the word “russia”. we have the right to be russian in russia, and we will defend it.”


i downloaded it to make sure it won’t disappear but it is still shared by navalny’s official youtube channel. btw, in this video, navalny is introduced in the caption as a “certified nationalist”.

here is another video navalny is not keen to share anymore, in which he compares muslims to cockroaches and flies and recommends shooting them with guns if swatters and shoes

here is a 2011 interview with navalny where he explains why he goes to the so-called “russian march”, a yearly nationalist gathering, and why he thinks it’s ok to collaborate with
HEALTH
Tony Breu
Tony Breu
@tony_breu
1/16
Why do B12 and folate deficiencies lead to HUGE red blood cells?

And, if the issue is DNA synthesis, why are red blood cells (which don't have DNA) the key cell line affected?

For answers, we'll have to go back a few billion years.


2/
RNA came first. Then, ~3-4 billion years ago, DNA emerged.

Among their differences:
🔹RNA contains uracil
🔹DNA contains thymine

But why does DNA contains thymine (T) instead of uracil (U)?

https://t.co/XlxT6cLLXg


3/
🔑Cytosine (C) can undergo spontaneous deamination to uracil (U).

In the RNA world, this meant that U could appear intensionally or unintentionally. This is clearly problematic. How can you repair RNA when you can't tell if something is an error?

https://t.co/bIZGviHBUc


4/
DNA's use of T instead of U means that spontaneous C → U deamination can be corrected without worry that an intentional U is being removed.

DNA requires greater stability than RNA so the transition to a thymine-based structure was beneficial.

https://t.co/bIZGviHBUc


5/
Let's return to megaloblastic anemia secondary to B12 or folate deficiency.

When either is severely deficient deoxythymidine monophosphate (dTMP*) production is hindered. With less dTMP, DNA synthesis is abnormal.

[*Note: thymine is the base in dTMP]

https://t.co/AnDUtKkbZh
HEALTH , PATHOPHYSIO
Advertisement
Eric Feigl-Ding
Eric Feigl-Ding
@DrEricDing
NEW—CDC was truly suffocated by Trump WH at every turn. Kyle McGowan, a former chief of staff at CDC, and his deputy, Amanda Campbell, witnessed WH dismissal of science, WH’s slow suffocation of CDC’s voice, meddling in messages & siphoning of CDC budget.
https://t.co/HeuNbUggiw


2) ““Everyone wants to describe the day that the light switch flipped—It didn’t happen that way—more of like a hand grasping something, and it slowly closes, closes, closes, closes until you realize that, middle of the summer, it has a complete grasp on everything at the CDC”

3) “Mr. McGowan and Ms. Campbell, both 34, say they tried to protect their colleagues against political meddling from WH and HHS but was largely stifled by the Trump administration.

4) “The White House insisted on reviewing — and often softening — the C.D.C.’s closely guarded coronavirus guidance documents, the most prominent public expression of its latest research and scientific consensus on the spread of the virus.”

5) “The documents were vetted not only by the White House’s coronavirus task force but by what felt to the agency’s employees like an endless loop of political appointees across Washington.
Mr. McGowan recalled a White House fixated on the economic implications of public health.
HEALTH
Dan Go
Dan Go
@FitFounder
If you want to get in the best shape of your life by 2023 read this:

1. Get 80-90% of your calories from single ingredient nutrient dense foods.

2. Avoid processed foods as much as possible because they're addictive, devoid of nutrients & leave you feeling empty.

3. Eating similar meals every day is an underrated way to get lean.

4. Lift weights 2-4x a week. Use progressive overload to build muscle.

5. Progressive overload is simply doing more through reps, weight or frequency,

6. Eat .8 to 1 gram of protein per pound of body weight. This helps you build & retain muscle. Eat protein with every meal.

7. Avoid trying to lose weight. Focus on creating good habits. The first is focused on an outcome the latter is focused on your lifestyle.

8. Your aim is to become the type of person who stays in shape. In order to change your body your identity must come along for the journey.

9. Eat your meals on a schedule. This will help train your hunger & circadian rhythms.

10. Replace snacking with water & drink it before meals. You usually want to snack because you're bored or dehydrated. Water also helps you feel full & increases energy.
HEALTH
Eli Tyre
Eli Tyre
@EpistemicHope
I know some people who seem (to me) more concerned with receiving VALIDATION for their mental health issues than solving them.

They seem to care most about other people BELIEVING their problems are real.

I'm curious about this.

Like, it's more important to them that people know how debilitating their anxiety is, than to overcome the anxiety.

Or it's important to them that others believe that they're actually depressed, not "just sad."

Or they want people buy into the narrative that they've been traumatized, and might be something like offended if someone minimizes that.

What do we make of this?

1. One possibility is that if solving the problems seems hopeless or even just really hard, you need external support to be able to cope.

If no one cuts you slack because of your mental health stuff, maybe you're in a really bad place, so you need people to believe you.
HEALTH

You May Also Like

Jaya_Upadhyaya
Jaya_Upadhyaya
@Jayalko1
SRI CHAMPAKADHAMA SWAMY, BANNERGHATTA HILL, BENGALURU (KAR)
#bharatmandir

The shrine is dedicated to Sri Vishnu along with Devi Lakshmi and Bhoodevi.
It is built in an area full of Champaka trees.
As champaka flowers are offered to Sri Vishnu here, it is called Champakadhama.


It is believed that King Janmejaya had sarpa-dosha. To get rid of it, he took bath in the nearby pond. He emerged with a golden body and sarpa-dosha was also removed. The pond is called Swarnamukhi and believed to have curative powers.
Sri Vishnu murti was consecrated by him.


It is also believed that this forest area was the Dandakaranya where Sri Ram stayed in exile.
Some believe that the original shrine was built by Pandavas.
The pushkarni/pond is emptied once a year so that the rock at the bottom (which has image of Anjaneya) may be worshipped.
ALL
\U0001f1fa\U0001f1f8I Support Our Military & Law Enforcement\U0001f1fa\U0001f1f8
🇺🇸I Support Our Milita...
@TheWiseOwl_AZ
1. There are more people added on the list of arrests and executions of famous people but no further intel is available at this time.

ARRESTS and EXECUTIONS OF FAMOUS PEOPLE 2020 UPDATED
Explanation of the latest military tribunal arrests and executions of famous people in 2020.

2. The tribunals are arresting these people in plain clothes. We saw the Obama’s arrest, although we didn’t know it was an arrest at the time. The arrest was done nonchalantly so as to not get noticed by the public.
All arrests of these famous people were done this way.

3. If the person is convicted of child sex trafficking, crimes against humanity or treason, they will be executed.
If the person arrested has evidence on someone else to help their prosecution, or is willing to help Trump, & they want to cooperate, they may be allowed to do so.

4. A sentence of execution down to life in prison may be accepted if their evidence is worth anything.
When a plea deal is done, the defendant must present evidence they have to make their sentence lighter. This information is given to the prosecution, defense, and to the judge.

5. If evidence is accepted, they are presented the plea deal. They will have to make a guilty plea to the crime with a video confession & written statement. That is how all plea deals work.

All famous people arrested were either treasonous or involved in satanic worship rituals.
CRIME
Advertisement
ashkan soltani
ashkan soltani
@ashk4n
BREAKING: @CommonsCMS @DamianCollins just released previously sealed #Six4Three @Facebook documents:

Some random interesting tidbits:

1) Zuck approves shutting down platform API access for Twitter's when Vine is released #competition


2) Facebook engineered ways to access user's call history w/o alerting users:

Team considered access to call history considered 'high PR risk' but 'growth team will charge ahead'. @Facebook created upgrade path to access data w/o subjecting users to Android permissions dialogue.


3) The above also confirms @kashhill and other's suspicion that call history was used to improve PYMK (People You May Know) suggestions and newsfeed rankings.

4) Docs also shed more light into @dseetharaman's story on @Facebook monitoring users' @Onavo VPN activity to determine what competitors to mimic or acquire in 2013.

https://t.co/PwiRIL3v9x
TECH
Mo Rajabifard
Mo Rajabifard
@morajabi
👨‍💻 Last resume I sent to a startup one year ago, sharing with you to get ideas:

- Forget what you don't have, make your strength bold
- Pick one work experience and explain what you did in detail w/ bullet points
- Write it towards the role you apply
- Give social proof

/thread


"But I got no work experience..."

Make a open source lib, make a small side project for yourself, do freelance work, ask friends to work with them, no friends? Find friends on Github, and Twitter.

Bonus points:

- Show you care about the company: I used the company's brand font and gradient for in the resume for my name and "Thank You" note.
- Don't list 15 things and libraries you worked with, pick the most related ones to the role you're applying.
-🙅‍♂️"copy cover letter"

"I got no firends, no work"

One practical way is to reach out to conferences and offer to make their website for free. But make sure to do it good. You'll get:

- a project for portfolio
- new friends
- work experience
- learnt new stuff
- new thing for Twitter bio

If you don't even have the skills yet, why not try your chance for @LambdaSchool? No? @freeCodeCamp. Still not? Pick something from here and learn https://t.co/7NPS1zbLTi
You'll feel very overwhelmed, no escape, just acknowledge it and keep pushing.
LIFE
Professor
Professor
@DillikiBiili
So friends here is the thread on the recommended pathway for new entrants in the stock market.

Here I will share what I believe are essentials for anybody who is interested in stock markets and the resources to learn them, its from my experience and by no means exhaustive..

First the very basic : The Dow theory, Everybody must have basic understanding of it and must learn to observe High Highs, Higher Lows, Lower Highs and Lowers lows on charts and their

Even those who are more inclined towards fundamental side can also benefit from Dow theory, as it can hint start & end of Bull/Bear runs thereby indication entry and exits.


Next basic is Wyckoff's Theory. It tells how accumulation and distribution happens with regularity and how the market actually

Dow theory is old but
SCREENERS , ALL , MARKETESSENTIALS