BC HEALTH
Saved by @SteveeRogerr

It's been 13 months since my craniocervical fusion surgery and 7 months since my tethered cord surgery. My diagnoses were craniocervical instability, tethered cord, ME/CFS, MCAS, POTS, and mold illness (which may or may be fully explained by MCAS). 1/n

 Before my first surgery, I couldn't sleep inside a house b/c of mold illness/MCAS. I got paralyzed, unable to speak, and barely able to breathe, sometimes 8 or more times a day. This could result from tilting my head back, speaking too much, a loud sound, a tap on the head. 2/n
Traction (pulling my head away from my body) brought me back from these episodes. I couldn't ever be left alone. I wasn't bedbound, but I could do essentially nothing for myself. 3/n
By that point, my symptoms were extreme even for CCI, and they were quite unusual for ME/CFS. But I started out with classic ME/CFS -- PEM, POTS, unrefreshing sleep, cognitive impairment, low NK-cell function, wacky cytokines, sky-high IGGs for a bunch of viruses. 4/n
The last year has been HARD. These surgeries are brutal and hard to recover from. Needing a second surgery when I hadn't yet fully recovered from the first was emotionally and physically rough. 5/n
But... Yesterday, I went for a three-mile hike with a friend. I was tired afterward, but no PEM. I can do strengthening exercises and push myself, hard. I'm starting to be able to write again. I can talk to people for as long as I like. I can care for myself and my new puppy. 6/n
My POTS is now under control with a fairly low dose of Mestinon. It's surprising that the POTS is still there, and it may be that I was getting tiny CSF leaks that self-healed. I'm hoping that I won't need the Mestinon after a while. 7/n
My mold reactivity is SO MUCH BETTER. I still have MCAS and I'm taking MCAS tx. But I can now live in my own house, which hasn't been possible for the last four years. I spent many months essentially homeless. I'm inexpressibly thrilled to be in the house I so love. 8/n
For me. I think the mold/MCAS was the primary driver of my illness. I believe that mold exposures led to inflammation, particularly around my brainstem. This inflammation involved the release of cytokines that are known to damage collagen. This damaged my neck ligaments. 9/n
That led to craniocervical instability. My neck ligaments *may* have gotten damaged initially from a couple of bad concussions I had as a kid -- not enough to cause sx, but enough to decrease the space for my brainstem and make me less tolerant of inflammation in that area. 10/n
I no longer meet the criteria for ME. 11/n
I don't believe that surgery is the solution to ME. Only a subset of ME patients have the same problems I have, and unless you do, and unless your sx are quite bad, you wouldn't be a candidate for surgery anyway. No neurosurgeon would operate on you. 12/n
I do think my experience, and that of other pts like me, suggests that we should be looking hard at the role of MCAS in ME, and also at what's going on with ME pts' connective tissue. Many ME patients have EDS, but I don't, and connective tissue was still my problem. 13/n
I also think we really need to look at the role of mold in ME. My MCAS sx were nearly exclusively in response to mold exposure, and before I developed CCI, I recovered almost completely through extreme mold avoidance. Mold plays a key role for many many ME pts. 14/n
I think one of the key lessons we're learning from ME is that these contested illnesses are closely related to one another. ME, EDS, IBS, Lyme, autoimmune disease, CCI, MCAS -- they're all pieces of a bigger story. 15/n
And long Covid is part of that story too. 16/n
So I think we need to break down the silos between these communities, ones that divide patients from one another and researchers from one another. 17/n
I don't have EDS, but EDS research is relevant to me. EDS patients are my brothers and sisters. 18/n
Doctors and researchers who want to help pts with one of these diagnoses need to learn about the rest too. 19/n
This is a project of co-liberation. Solidarity, friends. Let's work together. /fin

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#OurFavOnlineDoc \U0001fa7a\U0001f1f3\U0001f1ec\U0001f1ec\U0001f1e7\U0001f48e
#OurFavOnlineDoc 🩺🇳🇬🇬🇧...
@DrOlufunmilayo
HELLO: If you pee and every time you finish, your urine looks like this picture, you may have a serious medical illness.

Foamy urine especially if it is persistent and noticeable over time may mean you have a serious kidney problem.

Let’s talk about this today...
RT for others.


What are the features of a normal urine?

A normal urine should have a light yellow colour, painless, odourless (or faint smell), steady stream and should ideally not foam when you pee.

When there’s something wrong, then you see changes in all the above normal features of urine.

For instance if urine becomes very deep yellow, it may mean you are dehydrated;

If urine becomes painful or smells really really bad, it may mean you have an infection;

If urine has a poor stream, especially in a man, it may mean a prostate problem like cancer.

Do you get me?

So today let’s talk about Foamy Urine.

What are the things that can cause urine to suddenly be foamy. As I said in the first tweet, it MAY mean a serious medical illness like a serious kidney problem.

First things first- it does NOT always mean a problem but it may as well.

Now what are the causes of Foamy Urine:

1. SPEED-
If you pee really fast or with a lot of force, it may make your urine more foamy than usual. The speed and force makes the urine generate a lot of bubbles which tend to almost quickly disappear as it is formed in the toilet bowl.
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Ary Serpa Neto
Ary Serpa Neto
@a_serpaneto
The #RELAx trial has been published today in @JAMA. It was coordinated by Anna Algera. This thread is to explain the rationale, what we did, the findings and the meaning.
The rationale of #RELAx is based on the following

First, there is NO adequate evidence on the level of PEEP in non-ARDS patients. Most of the studies are old, conducted in post-surgical patients (short-term ventilation), and were not powered to detect differences in patient-centered

Second, despite the absence of evidence, the levels of PEEP used in non-ARDS patients increased over years, from 5 to 7/8 cmH2O, probably as a reflection of studies and practice in ARDS

Third, one IPDM showed that higher levels of PEEP could benefit more severe ARDS patients. However, opposite trends (higher mortality and longer ventilation) were found in mild ARDS with higher PEEP (despite not powered to be statistically

Fourth, most of the weaning protocols include PEEP ≤ 5 cmH2O as a criterion for readiness to wean. Theoretically, a standardized liberal strategy of higher PEEP could delay weaning in some
HEALTH
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Dr. Adam H. Domby
Dr. Adam H. Domby
@AdamHDomby
Now you know I love to sh-t in Harvard. But I also like accuracy. So I decided to go look at Harvard’s catalog to see its lack of military history that this article describes (they only teach history of pets it claims) and what I found shocked me! Shocked me! A thread: 1/


First off, Harvard students literally have multiple sections of military history that they can take listed. (It appears these ones are taught at MIT, so they might have to walk down the street for these) but... 2/


Say they want to stay on campus...they can only take numerous classes on war and diplomacy...3/


They have an entire class on Yalta. That’s right. An entire class on Yalta. 4/


But wait! There is more! They can take the British Empire, The Fall of the Roman Empire for those wanting traditional topics... 5/
HEALTH
AutisticSciencePerson
AutisticSciencePerson
@AutSciPerson
Me: Made a thread about how people don't understand hyperacusis and give advice that obviously I've already tried.

This person only a few tweets into the thread:


I only tweeted this because, like it or not, this is the general population's reaction to me talking about hyperacusis.

Similar replies happened when there was the whole "not clapping" article regarding Cambridge.

They're so quick to label disabilities as not real disabilities.

It's important to remember this when people may ask why we've never talked about this before, or why it's not talked about a lot.

Most people don't talk about their hyperacusis because if they do, people respond like this. So most of the time, honestly it's easier to say nothing

Yes I am petty enough to add screenshots of this toxicity to this thread:


Asking for accessibility is "pathetic." /s : )
HEALTH
Rebecca Fitzgerald Lab
Rebecca Fitzgerald Lab
@RFitzgerald_lab
Here is a tweetorial from our latest publication in @Annals_Oncology about longitudinal tracking of esophageal adenocarcinoma. #OesophagealCancer #EsophagealCancer https://t.co/QWvrzBXmK7 1/8

We sequenced 245 plasma samples from 97 patients with oesophageal adenocarcinoma using a 77 gene pan-cancer ctDNA panel. 2/8


Variants derived from previously characterised driver oesophageal adenocarcinoma genes had a significantly higher VAF than variants from other genes, indicating selection. 3/8


Peripheral blood cell samples were also sequenced for 78/97 patients. CHIP mutations were identified in 23% of cases, longitudinal tracking of CHIP variants suggested these variants were dynamic over time. 4/8


We found patients that were ctDNA positive post-surgery had a significantly poorer survival than ctDNA negative patients, and the elimination of CHIP variants improved the positive predictive value. 5/8
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Anshul Pandey
Anshul Pandey
@Anshulspiritual
BRAHMA VAIVARTA PURAN: IMPORTANCE AND CHARACTERISTICS.

This Puran introduces us to way of Vedas. On the request of Narad Muni Bhagwan Saavarni had preached this Puran. It is a summary of Dharma, Arth, Moksha etc.


Listening to this Puran one gets automatically attached to Vishnu and Shiva and realize that there is no difference between them. Vyasji divided this book into four parts. It has eighteen thousand shlokas. This whole book is in the form of dialogue between Suutji and Maharishi's.

The first part Brahmkhand, consists of Shrishti description. Here Shri is known as Para Brahma and description of Gokul is also mentioned, It also narrates the argument between Brahma and Narad in which both were defeated, and then Narad went to Shiva to attain more gyan.

Shivji advised him to go to Bhagwan Saavarni for this. Narad goes to Saavarni ashram to seek Knowledge and is totally amazed by the sorroundings.

Next is Prakriti khand which consists of dialogue between Narad and Saavarni where they discuss the

Importance of Shri Krishna through various stories. Then there is the discussion of Prakriti and its various hues. Listening to this gets you wealth.
Next is Ganesh Khand which describes the Punyak vrat done by Parvati ji. After this it narrates the birth of Kartikeya and Ganesh.
RELIGION
V\u0936\u0941\u0926\u094d\u0927\u093f
Vशुद्धि...
@V_Shuddhi
The first ever world map was sketched thousands of years ago by Indian saint
“Ramanujacharya” who simply translated the following verse from Mahabharat and gave the world its real face

In Mahabharat,it is described how 'Maharishi Ved Vyasa' gave away his divine vision to Sanjay


Dhritarashtra's charioteer so that he could describe him the events of the upcoming war.

But, even before questions of war could begin, Dhritarashtra asked him to describe how the world looks like from space.

This is how he described the face of the world:

सुदर्शनं प्रवक्ष्यामि द्वीपं तु कुरुनन्दन। परिमण्डलो महाराज द्वीपोऽसौ चक्रसंस्थितः॥
यथा हि पुरुषः पश्येदादर्शे मुखमात्मनः। एवं सुदर्शनद्वीपो दृश्यते चन्द्रमण्डले॥ द्विरंशे पिप्पलस्तत्र द्विरंशे च शशो महान्।

—वेद व्यास, भीष्म पर्व, महाभारत


Meaning:-

हे कुरुनन्दन ! सुदर्शन नामक यह द्वीप चक्र की भाँति गोलाकार स्थित है, जैसे पुरुष दर्पण में अपना मुख देखता है, उसी प्रकार यह द्वीप चन्द्रमण्डल में दिखायी देता है। इसके दो अंशो मे पीपल और दो अंशो मे विशाल शश (खरगोश) दिखायी देता है।


Meaning: "Just like a man sees his face in the mirror, so does the Earth appears in the Universe. In the first part you see leaves of the Peepal Tree, and in the next part you see a Rabbit."

Based on this shloka, Saint Ramanujacharya sketched out the map, but the world laughed
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Anu Satheesh
Anu Satheesh
@AnuSatheesh5
Thrikkangode Sree Randu Moorthy Temple
Ottappalam, Kerala. 🚩
#keralatemples

This is very unique temple as Shiva and Vishnu both are in the “linga” form in the same Garbhagriham. The Srikovil is in a circular pattern. Temple's Prathishta was done by Parasurama.


Mahadeva and Maha Vishnu in the same Srikovil is very rare Prathishta, but poojas are done separately Dhara is done to Maha Vishnu here. People suffering from “KAIVISHAM” and mental illness are fully cured on drinking a medicinal herb supplied by a nearby family here.


The root of the banyan tree around the Ayyappa Sannidhanam is said to have great powers for skin ailments.

Very ancient temple but was covered with forest for many years.
Later two persons Chakki and Chaathan, while cutting trees their axe hit on the nearby
@SriramKannan77


Vigrahams and it suddenly started bleeding. Later Devaprashnam was held and thus found out that these were murthy's of Shiva and Vishnu which was worshipped long back. And thus temple is constructed here.
Om Namah Sivaye
Om Namo Narayanaya
🕉🙏🕉
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Anu Satheesh \U0001f1ee\U0001f1f3
Anu Satheesh 🇮🇳...
@AnuSatheesh5
Srikanteshwara Temple,
#Nanjangud  #Karnatakatemples 🚩

Srikanteshwara Temple or
Nanjundeshwara Temple is a famous Shiva Temple located in Karnataka at the bank of river  Kapila. Temple is also called Varanasi of South. Nanjunda means one who has consumed poison.


Story is  related to the Samudra Mathanam when Paramashiva had to consume halahala.

Parashurama worshipped Mahadeva here to relieve himself from the curse of Mathru Hatya. While clearing the place to do poojas Parashurama's  axe hit the Shivalingam and it began bleeding, that


mark is still visible even today. Thus
it is also believed that Parashurama did Shiva Prathishta here

Sthala Puranam says that, once there was a demon named Keshi who disturbed the people in the area, after  getting blessing from Brahma Deva  and Mahavishnu. Mahadeva appeared


here and killed demon Keshi and blessed this place as Papa Vinashini. Whoever praying to Srikanteshwara or Nanjundeshwara, after bathing in the  Kabini River will be relieved from all sins.

Nanjundeshwaraya Namah
🙏🕉🙏
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Mo Rajabifard
Mo Rajabifard
@morajabi
👨‍💻 Last resume I sent to a startup one year ago, sharing with you to get ideas:

- Forget what you don't have, make your strength bold
- Pick one work experience and explain what you did in detail w/ bullet points
- Write it towards the role you apply
- Give social proof

/thread


"But I got no work experience..."

Make a open source lib, make a small side project for yourself, do freelance work, ask friends to work with them, no friends? Find friends on Github, and Twitter.

Bonus points:

- Show you care about the company: I used the company's brand font and gradient for in the resume for my name and "Thank You" note.
- Don't list 15 things and libraries you worked with, pick the most related ones to the role you're applying.
-🙅‍♂️"copy cover letter"

"I got no firends, no work"

One practical way is to reach out to conferences and offer to make their website for free. But make sure to do it good. You'll get:

- a project for portfolio
- new friends
- work experience
- learnt new stuff
- new thing for Twitter bio

If you don't even have the skills yet, why not try your chance for @LambdaSchool? No? @freeCodeCamp. Still not? Pick something from here and learn https://t.co/7NPS1zbLTi
You'll feel very overwhelmed, no escape, just acknowledge it and keep pushing.
LIFE