In medicine, reckoning with racism includes reappraising the very syntax we use every day. Proud to add my voice w/ @J_Ikeme and @RWGrantMD in this @JAMAInternMed pub addressing:

Does race/ethnicity belong in the first line of the patient

Some background: I’ve struggled with this question since early in medical school

Medical syntax is designed to communicate information in a predictable sequence with key elements prioritized to facilitate efficient communication and formation of an assessment and plan

2/
From preclinical lectures to Qbank questions to clerkship rotations, race/ethnicity was often prioritized in the same sentence as age + gender.

I grew accustomed to reading/hearing: a 70-year-old Black man w/ history of x, a 50-year-old Hispanic woman presented w/ y.

3/
However, when it came time for me to use race/ethnicity, there was always tension. Race/ethnicity are self/socially-ascribed identities that in clinical practice are almost always assumed by providers based on appearance. I was also concerned about the potential for bias

4/
I wondered how my own care would be impacted or not impacted by my ethnicity (Hispanic) – I have light skin so I’m not sure if my doctors would even identify me as such – but how would my care be different if I was presented as a 30-year-old Hispanic male?

5/
That said, I was taught race could have implications for the assessment and plan (e.g., eGFR – I’ll come back to this). Moreover, racial disparities are real and could inform a pt’s care. So, I reported race on a PRN basis, but still felt uneasy. I wondered what others did …

6/
In @JAMAInternMed, we get insight from Balderston et al. on this use of race in medicine. In 1200 admissions to an academic medical center, 33% of Black pts had their race documented in the first line of their admission note compared to 17% of white pts
https://t.co/GMKXsx6Z02
7/
They also found that Black clinicians had 58% lower odds of documenting race than white clinicians and attending physicians had 2.37 times greater odds of documenting race than resident physicians.

8/
Though this study was conducted at a single center and does not investigate *why* Black patients had race identified more often or *how* this impacts subsequent care, the differential documentation of race in the HPI merits further scrutiny.

9/
Fortunately, there has been much scrutiny and expertise dedicated to the (mis)representation of race in medicine this year – including this important work by Amutah et al.

https://t.co/8Ej4LvDi2a

10/
🔑 pts:
-race is not a meaningful scientific construct in the absence of context
-race is not a biologic category based on innate differences that produce unequal health outcomes.
-it is a social category that reflects the impact of unequal social experiences on health

11/
🔑 points (cont.):
-Unfortunately, race in medical education often misses the mark and can lead to race-based diagnostic bias or pathologizing race (see below table)

12/
Notably, they “are not arguing that race is irrelevant” but rather “that it can be a starting point to generate hypotheses about environmental exposures and social processes that produce disparities” and that “discussing race is essential to promoting an antiracist culture.”
13/
In another expert review, Borrell et al. similarly write it is “inappropriate to simply abandon the use of race in research and clinical practice ... these variables capture important epidemiologic information, including social determinants of health”

https://t.co/Yt28mUqPqg
14/
Key points:
- Race, ethnicity, and ancestry have a complex and intertwined relationship that demands nuanced analyses
- we should not assume that environmental, social, or genetic factors represent the only contributors to a given disease until causation has been proven

15/
Back to eGFR, and the use of race in research and clinical decision making, at large. My thoughts continue to evolve as a clinician and researcher on handling race in this context, but I want to provide one last article by Vyas et al:

https://t.co/aVM0k4GCEv

16/
This article provides a useful framework to eval race correction in clinical settings:
Is race correction based on robust evidence?
Is there a plausible causal mechanism for the racial difference?
Would implementing this correction relieve or exacerbate health inequities?

17/
As it applies to GFR, raceless markers are an ideal solution, but in lieu of ready access to these, I will continue to seek a nuanced understanding of how we can best estimate GFR in a manner that is based on robust evidence and doesn’t exacerbate health inequities.

18/
For many of the reasons made in these eloquent pieces (which I highly encourage reading), we feel that the rote documentation of race in the first line of the HPI is unlikely to serve a useful function and the practice of differential documentation offers potential for harm

19/
However, given the important implications related to structural racism and the potential that addressing race has in reducing health inequity, we suggest that race/ethnicity be documented as part of a complete social history, where it can be given appropriate context

20/20
@j_ikeme @RWGrantMD @RFRedberg @JAMAInternalMed @Adali_Mtz @brandon_s_scott @DestinyRoseman @Sarah_SchaeffMD @UCSFIMChiefs @CPSolvers @dereckwpaul @jbullockruns @AntiRacistUCSF @Neil_R_Powe @KBibbinsDomingo @tsaiduck77 @thegud_doc @Anand_Habib

More from Health

🚨Important changes to lockdown/self-isolation regulations from 5pm

The Health Protection (Coronavirus, Restrictions) (All Tiers and Self-Isolation) (England) (Amendment) Regulations 2021

£800 'house party' FPN & police can now access track & trace data

https://t.co/k9XCpVsXhC


“Large gathering offence”

As trailed by Home Secretary last week there is now a fixed penalty notice of £800 (or £400 if you pay within 14 days) for participating in an gathering of over 15 people in a private residence


Fixed Penalty Notices double for each subsequent “large gathering offence” up to £6,400

Compare:
- Ordinary fixed penalty notice is £200 or £100 if paid in 14 days
- Holding or being involved in the holding of a gathering of over 30 people is £10,000


Second big change:

Since September has been a legal requirement to sell-isolate if you test positive/notified by Track & Trace of exposure to someone else who tested positive

Police can now be given access to NHS Track & Trace data if for the purpose of enforcement/prosecution


This will make it easier for police to enforce people breaking self-isolation rules. Currently there has been practically no enforcement.

Data says only a small proportion of people meant to be self-isolating are fully doing so.
You gotta think about this one carefully!

Imagine you go to the doctor and get tested for a rare disease (only 1 in 10,000 people get it.)

The test is 99% effective in detecting both sick and healthy people.

Your test comes back positive.

Are you really sick? Explain below 👇

The most complete answer from every reply so far is from Dr. Lena. Thanks for taking the time and going through


You can get the answer using Bayes' theorem, but let's try to come up with it in a different —maybe more intuitive— way.

👇


Here is what we know:

- Out of 10,000 people, 1 is sick
- Out of 100 sick people, 99 test positive
- Out of 100 healthy people, 99 test negative

Assuming 1 million people take the test (including you):

- 100 of them are sick
- 999,900 of them are healthy

👇

Let's now test both groups, starting with the 100 people sick:

▫️ 99 of them will be diagnosed (correctly) as sick (99%)

▫️ 1 of them is going to be diagnosed (incorrectly) as healthy (1%)

👇
I think @SamAdlerBell in his quest to be the contrarian on Fauci gets several things wrong here. 1/


First, the failure last year actually was driven by the White House, the #Trump inner circle. Watch what's happening now, the US' scientific and public health infrastructure is creaking back to life. 2/

I think Sam underestimates the decimation of many of our health agencies over the past four years and the establishment of ideological control over them during the pandemic. 3/

I also am puzzled why Tony gets the blame for not speaking up, etc. Robert Redfield, Brett Giroir, Deb Birx, Jerome Adams, Alex Azar all could have done the same. 4/

Several of these people Bob Redfield, Brett Giroir, Alex Azar were led by craven ambition, Jerome Adams by cowardice, but I do think Deb Birx and Tony tried as institutionalists, insiders to make a difference. 5/

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