A vitally important thread. Much isnt new, but is so in the air we breathe we forget how RECENT it is & therefore how unaccustomed we r to coping w/it. At the risk of hijacking her great observatns, theyre pivotal to points others have made re: Institutional Evangelicalism...1/12

#SuvenLife – Niche R&D play..very high risk and very high reward…key is right allocation…

Jazz Pharma was quoting around $0.5 in 2009, today its $150 and Mcap of $8.5 Bn on Nasdaq..almost 300x in 11 years. 80% of its total sales ($2.1 Bn) come from single drug Xyrem.

Axovant Lifescience, bought Alzheimer molecule from GSK, repackaged it and done phase-3 trials. Before starting the trials, the valuation was $2 Bn, just before announcing the data, it rose to $3 Bn. One of the leading broker put the target of $12 Bn if the trials succeeded..

but it failed in phase-3 trials. Current Mcap is $120 Mn…

This is R&D for New Chemical Entity (NCE)…very high risk and very high reward…

Brain-related illnesses, also known as CNS diseases, afflict more than 2 billion people worldwide. Diseases of the brain and mind range

from Alzheimer’s, dementia, epilepsy, migraine, multiple sclerosis, neuro infections, Parkinson’s, psychosis, schizophrenia and stroke to brain injuries and various mental disorders. The global market or CNS therapeutics is projected to reach $137.7 billion by 2025.

#SuvenLife has 1 lead molecule SUVN-G3031 in phase-2 trials which is similar to Xyrem but superior features, 3 molecules completed phase-1 trials and starting phase-2 trials and 11 molecules in pre-clinical trials. All are related to CNS which is growing and uncluttered market

@The_Rumpus is open for essay submissions until February 28, so here’s a #RumpusEssays thread in which our amazing editors share what they would like to see in submissions. Give them a follow and send your essay our way via @submittable

Features Editor @happiestwerther is “still (forever) in love with the researched essays that teach me something about a subject while I also learn about a narrator.” #RumpusEssays

Assistant Features Editor @sarahkasbeer would like to see “essays with unexpected engines / innovative structures / emotional and intellectual depth / good ole narrative tension.” #RumpusEssays

Features Editor @kaytaybayy: “I'd love to see essays that are imbued with kinetic energy. I don't care what they're about. Just sweep me into your experiences and thoughts. Compel me to shake my dust off.” #RumpusEssays

Asst Feat Ed @DJ_theoretical: "I’d love to read about that weird, niche topic you’re obsessed with. Your Pog collection, those ribbon candies that seemingly only grandmas buy, your new obscure hobby. Distract me from the horrible big picture with your hyperfixations."

I was asked to do a tweet on how to be a good Minceir Ally. So here are my thoughts ... Other Minceiri are welcome to add.
Allies can do the actions you can.

Learn about Traveller Culture, history and issues affecting us from us not others. You can do this by checking Traveller org websites, chat with us, invite us to give inputs in your place of work.

Educate others and challenge Anti Traveller racism when you see it.

Get to know Travellers locally and local issues. Support the work of local and national Traveller orgs.

Get to know Travellers locally becoming friends. Invite Traveller children to your parties/playdates. Let your children go to Traveller children parties,playdates in their home.

Ok. I’ve organized my thoughts about the revival of Six Days in Fallujah. I want to approach this through the lens of someone who was IN Fallujah during 2004-2005, during some of the worst urban combat US Forces have ever experienced.

Let’s get a few things out of the way: the invasion of Iraq was a war crime. Period. Argue otherwise and I’ll block you. Does that make myself and others who fought war criminals? No, of course not. Did individual soldiers and Marines commit war crimes? Absolutely.

I’m someone who is deeply proud of my service. I tried my hardest to conduct myself as humanely as possible. I’m also someone who was forced to do things I’m not proud of to survive. Taking lives should never be a point of pride.

Iraq was a failure of our own making. Not only did we invade illegally, we did it without a plan. The vast majority of the insurgency were disaffected Iraqi soldiers without a job after we broke apart their military, not religious fanatics.

Yes, groups like AQI showed up to fight, but they came after we handed them a major propaganda victory by showing up in the first place and turning PMCs like Blackwater loose. There was little to no cultural sensitivity training.

This column by @ezraklein is very good and I agree with him 100% on policy -- we need a generous child allowance now. But I'm seeing this creeping argument on the left that it's just not important for women to work outside the home, and that's concerning.

Working 60 hours a week at two or three jobs? That's obviously awful. Being paid so poorly that you have no time for your family or leisure? That's not "dignity," that's exploitation. And it is single moms who bear the brunt of this.

But while the argument that at-home work is just as valuable as paid work may be morally correct, in our capitalist reality, not working outside of the home leaves women incredibly financially and physically vulnerable. It also leaves them isolated, depressed, and anxious.

wrote a whole book about this, but paid work is good for women. Not three jobs at $7.50 an hour to stay afloat. But work for pay, which offers a purpose outside of raising one's own children, and friends and coworkers and a $$ lifeline outside the nuclear family.

When women wind up financially dependent on men, good things do not follow. Of course there are individual stories of this working out just fine. But over the whole of a society, women as carers and men as earners is not a good system.