BC FOR LATER READ
Saved by @jay_millerjay

#IDTwitter #IDFellows
Introducing our new series: “IDFN top 10 articles every fellow should read”🔖

#1: SAB management
by @mmcclean1 @LeMiguelChavez
Reviewers @KaBourgi, @IgeGeorgeMD, @Courtcita, @MDdreamchaser

We know is subjective & expect feedback/future improvements 👇

 1. Clinical management of Staphylococcus aureus bacteremia: a review.
https://t.co/9tBCtp9mlP
👉 A must read written by Holland et al. where they review the evidence of the management of SAB.
2. Impact of Infectious Disease Consultation on Quality of Care, Mortality, and Length of Stay in Staphylococcus aureus Bacteremia: Results From a Large Multicenter Cohort Study.
https://t.co/XujO68pCuH
👉ID consult associated with reduced inpatient mortality.
3. Predicting Risk of Endocarditis Using a Clinical Tool (PREDICT): Scoring System to Guide Use of Echocardiography in the Management of Staphylococcus aureus Bacteremia
https://t.co/otcA1pxjAw
👉Predictive risk factors for infective endocarditis, and thus the need for TEE.
4. The Cefazolin Inoculum Effect Is Associated With Increased Mortality in Methicillin-Susceptible Staphylococcus aureus Bacteremia.
https://t.co/CQZiryVWZz
👉Presence of cefazolin inoculum effect in the infecting isolate was associated with an increase 30-day mortality.
5. Cefazolin versus anti-staphylococcal penicillins for treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a narrative review.
https://t.co/mwaQ6Aw5vX
👉Similar outcomes for treatment of MSSA but more side effects with the anti-staphylococcal penicillins.
6. Use of vancomycin or first-generation cephalosporins for the treatment of hemodialysis-dependent patients with methicillin-susceptible Staphylococcus aureus bacteremia.
https://t.co/Z7qxeZD8DM
👉Vancomycin had higher risk of treatment failure compared to cefazolin in MSSA BSI.
7. Daptomycin versus standard therapy for bacteremia and endocarditis caused by Staphylococcus aureus.
https://t.co/9W1sYv3VR0
👉RCT: dapto noninferior to SOC (B-lactams or vanco + gentamicin). Dapto resistance can emerge on treatment and more renal dysfunction in the SOC arm.
8. Adjunctive rifampicin for Staphylococcus aureus bacteremia (ARREST): a multicenter, randomized, double-blind, placebo-controlled trial.
https://t.co/SWsKR78njJ
👉 Rifampin addition not different to standard therapy in failure, recurrence or death.
9. Effect of Vancomycin or Daptomycin With vs Without an Antistaphylococcal β-Lactam on Mortality, Bacteremia, Relapse, or Treatment Failure in Patients With MRSA Bacteremia: A Randomized Clinical Trial. (CAMERA-2)
https://t.co/hNzJM4AOv5
👉more AKI with combination w/o benefit.
10. A Narrative Review of Early Oral Stepdown Therapy for the Treatment of Uncomplicated Staphylococcus aureus Bacteremia: Yay or Nay?
https://t.co/2ysr7lDYBW
👉 Oral step-down therapy can be an alternative in some select patients without complicated SAB.
Which article did we miss, or you would include in this list?
@BCMIDFellowship @DartmouthID @OhioState_ID @BIDMC_IDFellows @Tufs_ID @IUIDfellowship @UAB_ID @yaleIDfellows @ID_musc
@templeID1 @VUMC_IC @MayoclinicINFD @MGH_ID @UCLA_ID @MontefioreID @UNMC_ID @UVA_ID @OhioState_ID @UTSWinfDis @BrownIDprogram @RushCCH_ID @OHSU_ID
Also, check out this timeline of landmark trials.
Which trial would you like to add?
Next in "IDFN top 10 articles every fellow should read”:

- Infective Endocarditis 💙🦠

Coming soon: Osteoarticular infx , Enterobacterales infx, Transplant ID and more.

Check out the next tweet if you want to be an author of this series.
The IDFN is looking for content creators! Please retweet and share!

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🇺🇸 Jules 🇺🇸...
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Made by James Howard Kunstler

👇🏻👀

Kunstler is said to be one of the best thinkers and authors of our modern era. He’s well known as an expert in energy economics, among other topics.

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1) The election is re-adjudicated, fraud subtracted from the tally, and President Trump is declared the winner.

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4) The CIA is purged and reduced to a strictly analytical role for advising the executive.
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@cain_nate My friend Nate Cain and I have worked hundreds of hours with various politicians and legal groups trying to explain the election laws and how they fit together. There are many misperceptions of what happened during this election and what it means.

Simply put, our election laws are an intricate tapestry designed to ensure accuracy and prevent fraud. They work together like parts of a car. But when certain parts fail, the car is just a hunk of scrap iron and plastic. In this case critical parts failed.
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You do not have to prove fraud or intent, you just have to show that the election officials were unable to conduct an election that met the law and relevant certification requirements. In this case, the election does not come close to meeting accuracy requirements.
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These specifications are found deep in laws like FISMA, HAVA, and state adoptions of EAC guidance. 1 ballot error out of 125,000 or 1 position read error out of 500,000. Just look at the discrepancies between incoming ballot counts and total votes, the system fails.
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It is worse in the the swing states in Democrat strongholds but it is bad in many places. You add the apparent losses of ballots through the Mail and error rates in the ‘system’ are staggering. Why do we have these rules? Sure it is to prevent fraud, but......
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Operation Cupcake
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Wow, Morgan McSweeney again, Rachel Riley, SFFN, Center for Countering Digital Hate, Imran Ahmed, JLM, BoD, Angela Eagle, Tracy-Ann Oberman, Lisa Nandy, Steve Reed, Jon Cruddas, Trevor Chinn, Martin Taylor, Lord Ian Austin and Mark Lewis. #LabourLeaks #StarmerOut 24 tweet🧵

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The CEO Imran Ahmed worked closely with a number of Labour figures involved in the campaign to remove Jeremy as leader.

Rachel Riley is listed as patron. https://t.co/nGY5QrwBD0


SFFN claims that it has been “a project of the Center For Countering Digital Hate” since 4 May 2020. The relationship between the two organisations, however, appears to date back far longer. And crucially, CCDH is linked to a number of figures on the Labour right. #LabourLeaks

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VALENTINE DAY CELEBRATION: FRSC CAUTIONS MOTORISTS AGAINST EXCESSIVE SPEED, DRUNK DRIVING AND RECKLESSNESS ON THE ROAD.

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The Corps Public Education Officer, @BisiKazeem who made this public, said that the Corps Marshal, Dr Boboye Oyeyemi has directed Commanding Officers across board to double their efforts by ensuring massive deployment of Officers and Men for enhanced visibility,

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1/ I am seeing more and more founder secondary in venture rounds (Secondary = founders selling some of their shares before some other shareholders are able). Series B-D. I see both as an investor and through entrepreneur circles.

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How to get rich trading (without getting lucky)

Complete beginner’s guide to wealth of Rs 10 Cr in 10 years

Step 1: start trading live

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No amount of back-test, studies or indicators can substitute training your mind with screen time

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Start with trading capital of Rs 1 lakhs

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Max loss for the day, 1%, i.e. Rs 1000

Max 6 trades in a day

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