Old folk etymology connected it with Latin latere "to lie hidden," and a fable of Saturn.

https://t.co/yoKS1pS7bB

a higher and higher % of DMs, emails, etc. to me are from indians asking about their genetics. since there are 700 million indians on the internet. makes sense

i'll be publishing my 6K-word essay in indian genetics https://t.co/ycMGoZh13z

but some general points 1/n

- there's a lot of structure. which means you can look at an indian's genome and get an immediate sense of things and a little digging get's granularity very quickly

eg i guessed @suryasays family's jati after about 15 minutes (he was vague about this and had to ask mom)

- a lot of the variation is not partitioned geographically. very different from europe & china where geography is the dominant predictive variable.

indians have lots of structure which means non-geographical (jati) matter a lot. tamil brahmins more like UPites than other tamils

- the 'india-cline' pioneered by reich patterson is pretty explanatory. on one end you have west eurasian adjacent groups. jatts ppl in the NW and upper caste. and other end something away from them (more toward andamese). dalits, southerners etc.

- some groups are off the cline. that means they are not well modeled by the distribution. e.g.,

* parsies (75% iranian)
* bengalis (5-20% east asian)

Now, what exactly is an applied epidemiologist, and why are they needed? In the late 90s- early 2000's there were a series of articles in AJPH, AJE, JECH, and IJE dedicated to answering these questions. I'll focus on Stephen Thacker's review.

He states, “The applied epidemiologist is by definition an activist, moving rapidly from findings to policy, putting epi knowledge to good use. The 21st century epi must do all these things while maintaining a foundation of high-quality epi research and practice.”

Susser warns the field of what he considers “the black box paradigm… the current international focus on risk factor epidemiology.” He advocates for expanding our academic training to include socializing epis to “keep the improvement of the public’s health as a primary value”

Morabia argued that epidemiology has historically found its balance in the tension between the search for causal relations and the improvement of public health; overemphasis on either perspective puts epidemiology at risk of losing its value.

How does this play out in real life? I’ve been an applied epi for 13 years, working mainly in local, state, and federal health agencies. My work has focused on conducting cool analysis that lead to policy or systemic change.

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