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With 90% of American seniors now fully vaccinated, the overwhelming majority of the country's mortality risk has been, simply, eliminated. Even given Delta and flatlining vaccination rates, it is already a very different pandemic now. A thread (1/x).

There will be new cases, some of them severe and some leading ultimately to death. And there of course complications beyond death—even beyond hospitalization and severe disease.

If vaccination rates got close to 100%, we might be able to bring those numbers, in the future, close to zero. But even now we have probably eliminated 90% of all potential mortality from COVID-19. This makes it a very different kind of disease than we encountered last year.

First, "they kids are safe. Believe it or not, they always have been."

"It may sound strange, given a year of panic over school closures and reopenings, a year of masking toddlers and closing playgrounds and huddling in pandemic pods, that among children the mortality risk from COVID-19 is actually lower than from the flu."

Last week I spoke to over 5000 people in rural Georgia. Most were not vaccinated because they still had questions. EVERY question they asked was legitimate and important.

Stop telling people to “just get vaccinated” if you aren’t willing to put in the work to help them do it.

That “work” is MUCH more high touch than spouting condescension online.

“The unvaccinated” are not a monolith of defectors. They are people our health care system has long underserved - Black folks, rural folks, un and un/under insured folks and young folks.

That work requires daily acts to dispel and decrease the rampant disinformation people are contending with. It requires laws that prevent media organizations from willfully distributing disinformation about science during a pandemic when peoples lives depend on vaccine science.

That work requires interventions that can successfully vaccinate groups NOT individuals - like households, schools, churches work places - so that the protection of vaccination is SHARED among those most likely to encounter each other. Remember, vaccines protect you AND others.

That work requires incentives to vaccinate that begin locally, not trickle down from above. A lot of people are not aware of the large federal programs available to them. But they know their child care provider or grocery store attendant or neighbor - THEY are the influencers.

9 year old child with COVID pneumonia.
Florida

In this thread @EricTopol describes evidence from Israel of waning anti-#SARSCoV2 immunity months after mRNA #COVID19 #vaccination.
But as I wrote https://t.co/NZk0v3r6Dc the explanation is about timing. People ARE immune, but after months response goes
MORE

2/ ..into the B cell memory compartment, and circulating neutralizing antibody levels in blood plummet. THAT IS NORMAL with vaccines. The challenge is #DeltaVariant speed of replication is 2-3Xs faster than "normal" #SARSCoV2 so it outpaces antibody production from memory.