One of the most amazing things about the brain is how incredibly slow it is. Nerve impulses travel extremely slowly compared to the speed of electricity, and our fastest neurons can fire *a few* times per second . Compare that to the clock speed of a modern CPU, ~10M times faster

Yet we can produce complex behaviors in response to unexpected events in about 400-500ms (like catching an incoming object). Including muscle-brain roundtrip. This implies that each neuron involved in the computation fires at most a couple of times.
This inherent slowness, coupled with the constraint of real-time responses, must have shaped the algorithms developed by the brain in profound ways (in particular, this is likely why we need *so many* neurons). Intelligence developed on a computer might look very different.
In particular, we are unable to brute-force any problem. We solve constraint satisfaction problems via intuition and analogy. A chess master evaluates millions of times fewer positions than a computer program at a comparable level.
Our biological and experiential limitations *force* our brains to be *intelligent* -- to learn from few examples, to generalize strongly, to build complex solutions in few trials. Everything that is out of reach for AI today.

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https://t.co/6cRR2B3jBE
Viruses and other pathogens are often studied as stand-alone entities, despite that, in nature, they mostly live in multispecies associations called biofilms—both externally and within the host.

https://t.co/FBfXhUrH5d


Microorganisms in biofilms are enclosed by an extracellular matrix that confers protection and improves survival. Previous studies have shown that viruses can secondarily colonize preexisting biofilms, and viral biofilms have also been described.


...we raise the perspective that CoVs can persistently infect bats due to their association with biofilm structures. This phenomenon potentially provides an optimal environment for nonpathogenic & well-adapted viruses to interact with the host, as well as for viral recombination.


Biofilms can also enhance virion viability in extracellular environments, such as on fomites and in aquatic sediments, allowing viral persistence and dissemination.

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