"Well, we do try to stay ahead of the competition", said the barman. "And we are serving free pints every Wednesday from 6pm until 8pm. We have the cheapest beer in Mumbai."
Rahul Bhatia, Chief Executive of IndiGo Airlines - the so called cheap airline in India, after arriving at a hotel in Mumbai, went to the bar and asked for a pint of Guinness.
The barman nodded and said, "That will be ₹50 please, Mr. Bhatia."
"Well, we do try to stay ahead of the competition", said the barman. "And we are serving free pints every Wednesday from 6pm until 8pm. We have the cheapest beer in Mumbai."
"I see you don't seem to have a glass, so you'll probably need one of ours. That will be ₹150 please."
Rahul scowled, but paid up.
He took his drink and walked towards a seat. "Ah, you want to sit down?" said the barman.
"I think you may be too big for the seat Sir, can I ask you to sit in this frame please."
Rahul attempts to sit down, but the frame is too small and when he can't squeeze in
"I'm afraid if you can't fit in the frame, you'll have to pay an extra surcharge of ₹250 for your seat sir."
Rahul swore to himself, but paid up.
"I see that you have brought your laptop with you," added the barman.
Rahul was so incensed that he walked back to the bar, slammed his drink on the counter and yelled, "This is ridiculous, I want to speak to the manager!"
"I see you want to use the counter..." says the barman,
Rahul's face was red with rage. "Do you know who I am?"
"Of course I do, Mr. Bhatia!"
"I've had enough! What sort of Hotel is this? I come in for a quiet drink and you treat me like this?
I insist on speaking to a manager!"
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@EricTopol @NBA @StephenKissler @yhgrad B.1.1.7 reveals clearly that SARS-CoV-2 is reverting to its original pre-outbreak condition, i.e. adapted to transgenic hACE2 mice (either Baric's BALB/c ones or others used at WIV labs during chimeric bat coronavirus experiments aimed at developing a pan betacoronavirus vaccine)
@NBA @StephenKissler @yhgrad 1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2
@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj
@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o
@NBA @StephenKissler @yhgrad 1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
1. From Day 1, SARS-COV-2 was very well adapted to humans .....and transgenic hACE2 Mice
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 30, 2021
"we generated a mouse model expressing hACE2 by using CRISPR/Cas9 knockin technology. In comparison with wild-type C57BL/6 mice, both young & aged hACE2 mice sustained high viral loads... pic.twitter.com/j94XtSkscj
@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2
1. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2!
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 2, 2021
2 papers:
Human\u2013viral molecular mimicryhttps://t.co/irfH0Zgrve
Molecular Mimicryhttps://t.co/yLQoUtfS6s https://t.co/lsCv2iMEQz
@NBA @StephenKissler @yhgrad B.1.1.7 has an unusually large number of genetic changes, ... found to date in mouse-adapted SARS-CoV2 and is also seen in ferret infections.
https://t.co/9Z4oJmkcKj

@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o
