UK Government - The work for US ...although you'd never think this by the way they act.....maybe they worship Santa 'Klaus'...🙄🤨

I've been seeing a lot of discussion around the dosage gaps recommended by government for the Astra/Oxford & Pfizer/BioNTech vaccines. My thoughts on the potential benefits & risks of such an approach, and the need for much greater transparency around these decisions. Thread.

The UK govt announced recently that both the Oxford & BioNTech vaccines would be now administered with a gap of between 4-12 weeks (so prioritise administration of first dose, given limited resources).

What is the basis of this?

The basis that's been discussed seems to be that
1) the first dose is likely to confer some degree of protection against disease, so better to roll this out as fast as possible, and
2) that for Oxford/Astra efficacy may be higher when the gap between doses is greater.

I discuss some of the technical details around the Oxford trial below for those interested in these. If you'd just like a summary of this, please skip to the summary tweet titled 'SUMMARY'.

What does published evidence show? The Astra/Oxford data are a bit messy because of protocol changes during the trial. This is because the trial was originally planned as a single dose trial, but a booster dose was added when developers realised that this would likely help.

Schoen is pretending courtroom "due process" must be followed--after meeting with some of the jurors to plan strategy last night.

Schoen accuses Democrats of editing videos and taking comments out of contexts, after showing edited videos of Democrats and taking their comments out of context. I guess he wanted us to know he knows what he's talking about.

Schoen is showing longer clips of Trump speeches. The additional footage doesn't help Trump's case, unless you're a racist insurrectionist.

Yeah? Well what about YOUR whataboutism?

Schoen REALLY doesn't like Senator Warren.

It's because Trumpists love attacking Senator Warren.

Gee, it's almost like he thinks Senator Warren is being impeached.

New from me and @MarkMorales51: Cuomo said 'he can destroy me': NY assemblyman alleges governor threatened him over nursing homes scandal

Democratic NY Assemblyman Ron Kim told CNN that Gov. Cuomo called last Thursday to “threaten my career if I did not cover up for Melissa [DeRosa] and what she said.” Cuomo also said “I hadn't seen his wrath and that he can destroy me,” according to Kim.

Kim's wife told CNN she overheard parts of the phone call and heard Cuomo say, "Who do you think you are?" as well as the words, "my wrath," and that immediately after the phone call, her husband told her: "The governor threatened to destroy my life."

CNN first reached out to Cuomo's office for comment on TUESDAY. In a written statement, his communications director did not directly respond to or deny Kim's allegation of threats from the governor in a written statement.

Ultimately, Cuomo's office sent another statement from senior adviser Rich Azzopardi late Wednesday morning that said: "Kim's assertion that the governor said he would 'destroy him' is false."