The republican speeches today are familiar to any abuse survivor.

"I hate that you made me hit you. I've never hit anyone before, so that's how awful you've been to me to make me do that. And the way you keep pushing this, it feels like you're trying to make me go there again."

More from For later read

Moderna's mRNA-1273 & Pfizer's BNT162b2 consist of mRNA 3821 nucleotides long encoding *all* 1273 amino acids of the Spike including a 2 Proline-stabilized RBD. This is a plain English Description of the code:
https://t.co/w7koHyMJjL

The article mentions a “10 nucleotide linker” (GCAUAUGACU) in the poly-A tail. This is described in the patent link below (Modification of RNA, producing an increased transcript stability and translation

Here is a link to the full mRNA code if you wish to download it, blast it or make up a batch in your garage

The mRNA sequences used for Moderna mRNA-1273 & Pfizer BNT162b2 mRNA vaccines for COVID-19 (Direct link in Word Format). WHO International Nonproprietary Name Program # 11889 "Messenger RNA encoding the full-length SARS-CoV-2 spike glycoprotein"https://t.co/zTb7B0Apic pic.twitter.com/8tZxAZWI5S
— Roland Baker (@RolandBakerIII) December 24, 2020

An overview of the encoded spike

Moderna's mRNA-1273 & Pfizer's BNT162b2 consist of mRNA 3821 nucleotides long encoding *all* 1273 amino acids of the Spike including a 2 Proline-stabilized RBD and this includes the NTD (blue in monomer, dark gray in trimer attached to antibodies). AA 64, 66, 187, 213, 214 red. pic.twitter.com/4MX1ByAsrR
— Roland Baker (@RolandBakerIII) December 19, 2020

Initial mouse

News: NIH-Moderna investigational COVID-19 vaccine shows promise in mouse studies https://t.co/7JYuUyZT45
— NIH (@NIH) August 5, 2020

John Hayward
@Doc_0

Time once again to emphasize the differences between totalitarianism, authoritarianism, and fascism. They're often used as synonyms but they are different, although they do tend to lead to each other. Order one, and the other two are usually delivered soon enough.

Totalitarianism is best understood as the politicization of everything. Every facet of life is infused with political meaning... and subjected to political control. There is little room for privacy or individualism. Every word and deed is seen as a political action.

Totalitarianism does *not* require authoritarian government, although it usually leads to such. You can be totalitarian without having any real government power at all, enforcing your political will through mob actions and corporate power. Examples from recent history abound.

Totalitarianism is the easiest of the three deadly "isms" to slide into, because it can easily be disguised with claims of its good intentions. Totalitarians usually claim to be motivated by the Greater Good. They claim to represent the interests of sympathetic victims.

Totalitarians claim that society is unjust and must be corrected by force. Before they gain the power to become authoritarians, they often assert the right to use force outside of the law because the government is corrupt or serves the interests of their ideological enemies.

A Brian For All Four S...
@bguthrie

So, here's my contrarian take on Why Trunk-Based Development Is Great But Probably Won't Work For You. Buckle up, it's a long one.

From time to time I talk about, or boost someone else's discussion of, "classical" continuous integration/trunk-based development/push-to-master/whatever. I do this because I've personally worked like this and I genuinely think it's a marvelous way to write software.

I've also, at this point in my career, failed—a bunch of times!—to bring this technique into practical use on the teams and organizations I've worked with. As a result, while I still do it myself, I don't focus as much on encouraging it in others.

The technoculture that's presently in vogue is what I think of as async/individual—optimize for the individual, performance-manage the individual, decouple the individual from others so they can be their best, most productive, most heroic selves.

This is in contrast to what I think of as sync/team—a culture that leans into interdependence and collaboration. If you've never worked on a team that collaborates very closely every day for months or years on end (and likes it) you've likely not experienced a team like this.

John Sifton
@johnsifton

With Myanmar, it seems that some are raising questions about the efficacy of sanctions and concerns about unintended consequences. It’s time for a “Myth and Realities” guide. THREAD. #WhatsHappeningInMyanmar

Myth: Human rights groups are calling for blanket sanctions on Myanmar.

Reality: This is false. Most human rights groups are calling for targeted measures directed solely at the military of Myanmar and companies it owns and which give revenue directly to it.

We are talking about the conglomerates and corporations that control the country’s natural resources, including the concessions for extractive sectors (oil and gas, timber, and mining of gemstones, jade, and valuable metals).

We’re calling on governments to focus on revenues and block transactions or seize government or state assets only where there is credible information that the military or its leaders are looting or acquiring state revenues or redirecting it to them.

Myth: Even if tailored narrowly, targeted sanctions will have major negative impacts on the people of Myanmar.

Reality: There are all kinds of ways to prevent unintended consequences on the broader Myanmar economy.

Angus Johnston
@studentactivism

I’ve asked Byers to clarify, but as I read this tweet, it seems that Bret Stephens included an unredacted use of the n-word in his column this week to make a point, and the column got spiked—maybe as a result?

Stephens goes on in his column (which never saw light of day) to cite famous Lee Atwater quote that uses racial slur, and which NYT has cited \u201cat least seven times.\u201d

"Is this now supposed to be a scandal?\u201d he asks.

...
— Dylan Byers (@DylanByers) February 11, 2021

Four times. The column used the n-word (in the context of a quote) four times. https://t.co/14vPhQZktB

That is correct. In his draft he quotes Atwater using the word (4 times) and he does not redact it.
— Dylan Byers (@DylanByers) February 11, 2021

For context: In 2019, a Times reporter was reprimanded for several incidents of racial insensitivity on a trip with high school students, including one in which he used the n-word in a discussion of racial slurs.

That incident became public late last month, and late last week, after 150 Times employees complained about how it had been handled, the reporter in question resigned.

In the course of all that, the Times' executive editor said that the paper does not "tolerate racist language regardless of intent.” This was the quote that Bret Stephens was pushing back against in his column. (Which, again, was deep-sixed by the paper.)