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Moderna's mRNA-1273 & Pfizer's BNT162b2 consist of mRNA 3821 nucleotides long encoding *all* 1273 amino acids of the Spike including a 2 Proline-stabilized RBD. This is a plain English Description of the code:
https://t.co/w7koHyMJjL
The article mentions a “10 nucleotide linker” (GCAUAUGACU) in the poly-A tail. This is described in the patent link below (Modification of RNA, producing an increased transcript stability and translation
Here is a link to the full mRNA code if you wish to download it, blast it or make up a batch in your garage
An overview of the encoded spike
Initial mouse
https://t.co/w7koHyMJjL
The article mentions a “10 nucleotide linker” (GCAUAUGACU) in the poly-A tail. This is described in the patent link below (Modification of RNA, producing an increased transcript stability and translation
Here is a link to the full mRNA code if you wish to download it, blast it or make up a batch in your garage
The mRNA sequences used for Moderna mRNA-1273 & Pfizer BNT162b2 mRNA vaccines for COVID-19 (Direct link in Word Format). WHO International Nonproprietary Name Program # 11889 "Messenger RNA encoding the full-length SARS-CoV-2 spike glycoprotein"https://t.co/zTb7B0Apic pic.twitter.com/8tZxAZWI5S
— Roland Baker (@RolandBakerIII) December 24, 2020
An overview of the encoded spike
Moderna's mRNA-1273 & Pfizer's BNT162b2 consist of mRNA 3821 nucleotides long encoding *all* 1273 amino acids of the Spike including a 2 Proline-stabilized RBD and this includes the NTD (blue in monomer, dark gray in trimer attached to antibodies). AA 64, 66, 187, 213, 214 red. pic.twitter.com/4MX1ByAsrR
— Roland Baker (@RolandBakerIII) December 19, 2020
Initial mouse
News: NIH-Moderna investigational COVID-19 vaccine shows promise in mouse studies https://t.co/7JYuUyZT45
— NIH (@NIH) August 5, 2020
1. A little DRASTIC Project you may be able to help with?
We want to collate all references to DRASTIC in academic papers & media articles
Here are a few:
medium article by @emmecola
thorough report by @netpoette
@ColinDavdButler 's Paper
Please add any links to this thread. Tks!
2. More References
Papers by @MonaRahalkar and @BahulikarRahul
Papers by @Rossana38510044 and @ydeigin
Medium articles & papers by
@gdemaneuf & @Rdemaistre
Papers by @flavinkins (Daoyu Zhang)
Papers by "Anon" & "interneperson"
French News - le Monde
Can anyone remember any more?
3. More References
Papers & Blog Posts by @Harvard2H (Sirotkin & Sirotkin)
260 Questions for WHO collated by @billybostickson
If you find mentions of our individual names or "DRASTIC" in Papers or News, please forward here to this thread as links or screenshots.
Histoire du COVID-19 – chapitre 6 - Partie 2 : Pourquoi le séquençage complet du virus RaTG13 n'a pas été communiqué par Shi Zheng Li avant février 2020 ? https://t.co/MYEZZSAzaE
SARS-CoV-2: lab-origin hypothesis gains traction
BY ANNETTE GARTLAND ON OCTOBER 12, 2020
https://t.co/sPs1y8Herg
We want to collate all references to DRASTIC in academic papers & media articles
Here are a few:
medium article by @emmecola
thorough report by @netpoette
@ColinDavdButler 's Paper
Please add any links to this thread. Tks!
2. More References
Papers by @MonaRahalkar and @BahulikarRahul
Papers by @Rossana38510044 and @ydeigin
Medium articles & papers by
@gdemaneuf & @Rdemaistre
Papers by @flavinkins (Daoyu Zhang)
Papers by "Anon" & "interneperson"
French News - le Monde
Can anyone remember any more?
3. More References
Papers & Blog Posts by @Harvard2H (Sirotkin & Sirotkin)
260 Questions for WHO collated by @billybostickson
If you find mentions of our individual names or "DRASTIC" in Papers or News, please forward here to this thread as links or screenshots.
Histoire du COVID-19 – chapitre 6 - Partie 2 : Pourquoi le séquençage complet du virus RaTG13 n'a pas été communiqué par Shi Zheng Li avant février 2020 ? https://t.co/MYEZZSAzaE
SARS-CoV-2: lab-origin hypothesis gains traction
BY ANNETTE GARTLAND ON OCTOBER 12, 2020
https://t.co/sPs1y8Herg
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THREAD: 12 Things Everyone Should Know About IQ
1. IQ is one of the most heritable psychological traits – that is, individual differences in IQ are strongly associated with individual differences in genes (at least in fairly typical modern environments). https://t.co/3XxzW9bxLE
2. The heritability of IQ *increases* from childhood to adulthood. Meanwhile, the effect of the shared environment largely fades away. In other words, when it comes to IQ, nature becomes more important as we get older, nurture less. https://t.co/UqtS1lpw3n
3. IQ scores have been increasing for the last century or so, a phenomenon known as the Flynn effect. https://t.co/sCZvCst3hw (N ≈ 4 million)
(Note that the Flynn effect shows that IQ isn't 100% genetic; it doesn't show that it's 100% environmental.)
4. IQ predicts many important real world outcomes.
For example, though far from perfect, IQ is the single-best predictor of job performance we have – much better than Emotional Intelligence, the Big Five, Grit, etc. https://t.co/rKUgKDAAVx https://t.co/DWbVI8QSU3
5. Higher IQ is associated with a lower risk of death from most causes, including cardiovascular disease, respiratory disease, most forms of cancer, homicide, suicide, and accident. https://t.co/PJjGNyeQRA (N = 728,160)
1. IQ is one of the most heritable psychological traits – that is, individual differences in IQ are strongly associated with individual differences in genes (at least in fairly typical modern environments). https://t.co/3XxzW9bxLE
2. The heritability of IQ *increases* from childhood to adulthood. Meanwhile, the effect of the shared environment largely fades away. In other words, when it comes to IQ, nature becomes more important as we get older, nurture less. https://t.co/UqtS1lpw3n
3. IQ scores have been increasing for the last century or so, a phenomenon known as the Flynn effect. https://t.co/sCZvCst3hw (N ≈ 4 million)
(Note that the Flynn effect shows that IQ isn't 100% genetic; it doesn't show that it's 100% environmental.)
4. IQ predicts many important real world outcomes.
For example, though far from perfect, IQ is the single-best predictor of job performance we have – much better than Emotional Intelligence, the Big Five, Grit, etc. https://t.co/rKUgKDAAVx https://t.co/DWbVI8QSU3
5. Higher IQ is associated with a lower risk of death from most causes, including cardiovascular disease, respiratory disease, most forms of cancer, homicide, suicide, and accident. https://t.co/PJjGNyeQRA (N = 728,160)