"The One That Didn't Work Out." Startup founders, you know what I mean: We spend years on a product - starting it from scratch, recruiting friends, getting it off the ground. We think we'll spend years on this. This is the one. We tell that to ourselves, investors, and friends
10 years ago today, I had the idea for an app I thought was interesting. I called it Bump, and sent this email to Andy Huibers.
— David Lieb (@dflieb) October 13, 2018
Here\u2019s a thread with some memories and lessons learned in the last 10 years. pic.twitter.com/jjfOrOlOVj
Btw, Groupon is a public co worth ~$2B. Obv it's not Google but @andrewmason still made it a huge success. This interview is compelling and honest, though ignore the headline. "The Quick Rise and Even Faster Fall of Groupon, Through the Eyes of Its CEO" https://t.co/7aE945ngLG
— Andrew Chen (@andrewchen) October 14, 2018
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— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 30, 2021
"we generated a mouse model expressing hACE2 by using CRISPR/Cas9 knockin technology. In comparison with wild-type C57BL/6 mice, both young & aged hACE2 mice sustained high viral loads... pic.twitter.com/j94XtSkscj
@NBA @StephenKissler @yhgrad 2. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2
1. High Probability of serial passaging in Transgenic Mice expressing hACE2 in genesis of SARS-COV-2!
— Billy Bostickson \U0001f3f4\U0001f441&\U0001f441 \U0001f193 (@BillyBostickson) January 2, 2021
2 papers:
Human\u2013viral molecular mimicryhttps://t.co/irfH0Zgrve
Molecular Mimicryhttps://t.co/yLQoUtfS6s https://t.co/lsCv2iMEQz
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https://t.co/9Z4oJmkcKj
@NBA @StephenKissler @yhgrad We adapted a clinical isolate of SARS-CoV-2 by serial passaging in the ... Thus, this mouse-adapted strain and associated challenge model should be ... (B) SARS-CoV-2 genomic RNA loads in mouse lung homogenates at P0 to P6.
https://t.co/I90OOCJg7o